Skip to main content
Top
Published in: Clinical Orthopaedics and Related Research® 10/2011

01-10-2011 | Clinical Research

The Presence of an Ossific Nucleus Does Not Protect Against Osteonecrosis After Treatment of Developmental Dysplasia of the Hip

Authors: Andreas Roposch, MD, MSc, FRCS, Odeh Odeh, MB, BCh, Andrea S. Doria, MD, MSc, PhD, John H. Wedge, OC, MD, FRCSC

Published in: Clinical Orthopaedics and Related Research® | Issue 10/2011

Login to get access

Abstract

Background

Osteonecrosis (ON) is a major complication after treatment of developmental dysplasia of the hip (DDH). Several studies have explored the absence of the femoral head ossific nucleus at the time of hip reduction as a risk factor for the development of ON, but findings have been inconsistent.

Questions/purposes

We therefore determined the incidence of ON in children who underwent reduction of a dislocated hip in the presence or absence of the ossific nucleus.

Patients and Methods

We retrospectively reviewed the radiographs of 105 hips in 89 patients treated for DDH at the age of 18 months or younger. Radiographs were graded for the presence of the ossific nucleus at the time of hip reduction and for the presence of ON, as graded by the Bucholz and Ogden classification, for patients at a mean age of 10 years. We used log-binomial regression to estimate if the presence of the ossific nucleus was associated with a lower incidence of ON.

Results

We identified ON in 37 of the 105 hips (35%). The incidence of ON at 10 years was 40% in the absence of the ossific nucleus and 32% in the presence of the ossific nucleus (adjusted relative risk, 0.86; 95% confidence interval, 0.36–1.81). When only radiographic changes of Grade II and greater were considered ON, the risk was still not increased (relative risk, 1.26; 95% confidence interval, 0.62–2.56).

Conclusion

Patients with an ossific nucleus at the time of hip reduction showed a slight tendency toward better outcomes. The ossific nucleus did not protect for ON.

Level of Evidence

Level III, prognostic study. See Guidelines for Authors for a complete description of levels of evidence.
Literature
1.
go back to reference Agus H, Omeroglu H, Ucar H, Bicimoglu A, Turmer Y. Evaluation of the risk factors of avascular necrosis of the femoral head in developmental dysplasia of the hip in infants younger than 18 months of age. J Pediatr Orthop B. 2002;11:41– 46.PubMed Agus H, Omeroglu H, Ucar H, Bicimoglu A, Turmer Y. Evaluation of the risk factors of avascular necrosis of the femoral head in developmental dysplasia of the hip in infants younger than 18 months of age. J Pediatr Orthop B. 2002;11:41– 46.PubMed
2.
go back to reference Bucholz RW, Ogden JA. Patterns of Ischemic Necrosis of the Proximal Femur in Nonoperatively Treated Congenital Hip Disease. St Louis, MO: CV Mosby Company; 1978:43–63. Bucholz RW, Ogden JA. Patterns of Ischemic Necrosis of the Proximal Femur in Nonoperatively Treated Congenital Hip Disease. St Louis, MO: CV Mosby Company; 1978:43–63.
3.
go back to reference Carney BT, Clark D, Minter CL. Is the absence of the ossific nucleus prognostic for avascular necrosis after closed reduction of developmental dysplasia of the hip? J Surg Orthop Adv. 2004;13:24–29.PubMed Carney BT, Clark D, Minter CL. Is the absence of the ossific nucleus prognostic for avascular necrosis after closed reduction of developmental dysplasia of the hip? J Surg Orthop Adv. 2004;13:24–29.PubMed
4.
go back to reference Clarke NM, Jowett AJ, Parker L. The surgical treatment of established congenital dislocation of the hip: results of surgery after planned delayed intervention following the appearance of the capital femoral ossific nucleus. J Pediatr Orthop. 2005;25:434–439.PubMedCrossRef Clarke NM, Jowett AJ, Parker L. The surgical treatment of established congenital dislocation of the hip: results of surgery after planned delayed intervention following the appearance of the capital femoral ossific nucleus. J Pediatr Orthop. 2005;25:434–439.PubMedCrossRef
5.
go back to reference Fleissner PR Jr, Ciccarelli CJ, Eilert RE, Chang FM, Glancy GL. The success of closed reduction in the treatment of complex developmental dislocation of the hip. J Pediatr Orthop. 1994;14:631–635.PubMedCrossRef Fleissner PR Jr, Ciccarelli CJ, Eilert RE, Chang FM, Glancy GL. The success of closed reduction in the treatment of complex developmental dislocation of the hip. J Pediatr Orthop. 1994;14:631–635.PubMedCrossRef
6.
go back to reference Kim HW, Morcuende JA, Dolan LA, Weinstein SL. Acetabular development in developmental dysplasia of the hip complicated by lateral growth disturbance of the capital femoral epiphysis. J Bone Joint Surg Am. 2000;82:1692–1700.PubMed Kim HW, Morcuende JA, Dolan LA, Weinstein SL. Acetabular development in developmental dysplasia of the hip complicated by lateral growth disturbance of the capital femoral epiphysis. J Bone Joint Surg Am. 2000;82:1692–1700.PubMed
7.
go back to reference Konigsberg DE, Karol LA, Colby S, O’Brien S. Results of medial open reduction of the hip in infants with developmental dislocation of the hip. J Pediatr Orthop. 2003;23:1–9.PubMedCrossRef Konigsberg DE, Karol LA, Colby S, O’Brien S. Results of medial open reduction of the hip in infants with developmental dislocation of the hip. J Pediatr Orthop. 2003;23:1–9.PubMedCrossRef
8.
go back to reference Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics. 1977;33:159–174.PubMedCrossRef Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics. 1977;33:159–174.PubMedCrossRef
9.
go back to reference Luhmann SJ, Bassett GS, Gordon JE, Schootman M, Schoenecker PL. Reduction of a dislocation of the hip due to developmental dysplasia: implications for the need for future surgery. J Bone Joint Surg Am. 2003;85:239–243.PubMed Luhmann SJ, Bassett GS, Gordon JE, Schootman M, Schoenecker PL. Reduction of a dislocation of the hip due to developmental dysplasia: implications for the need for future surgery. J Bone Joint Surg Am. 2003;85:239–243.PubMed
10.
go back to reference Luhmann SJ, Schoenecker PL, Anderson AM, Bassett GS. The prognostic importance of the ossific nucleus in the treatment of congenital dysplasia of the hip. J Bone Joint Surg Am. 1998;80:1719–1727.PubMed Luhmann SJ, Schoenecker PL, Anderson AM, Bassett GS. The prognostic importance of the ossific nucleus in the treatment of congenital dysplasia of the hip. J Bone Joint Surg Am. 1998;80:1719–1727.PubMed
11.
go back to reference Roposch A, Stohr KK, Dobson M. The effect of the femoral head ossific nucleus in the treatment of developmental dysplasia of the hip: a meta-analysis. J Bone Joint Surg Am. 2009;91:911–918.PubMedCrossRef Roposch A, Stohr KK, Dobson M. The effect of the femoral head ossific nucleus in the treatment of developmental dysplasia of the hip: a meta-analysis. J Bone Joint Surg Am. 2009;91:911–918.PubMedCrossRef
12.
go back to reference Salter RB. Innominate osteotomy in the treatment of congenital dislocation and subluxation of the hip. J Bone Joint Surg Br. 1961;43:518–539. Salter RB. Innominate osteotomy in the treatment of congenital dislocation and subluxation of the hip. J Bone Joint Surg Br. 1961;43:518–539.
13.
go back to reference Segal LS, Boal DK, Borthwick L, Clark MW, Localio AR, Schwentker EP. Avascular necrosis after treatment of DDH: the protective influence of the ossific nucleus. J Pediatr Orthop. 1999;19:177–184.PubMed Segal LS, Boal DK, Borthwick L, Clark MW, Localio AR, Schwentker EP. Avascular necrosis after treatment of DDH: the protective influence of the ossific nucleus. J Pediatr Orthop. 1999;19:177–184.PubMed
14.
go back to reference Spence G, Hocking R, Wedge JH, Roposch A. The effect of innominate and varus-derotation osteotomy on acetabular development in developmental dysplasia of the hip. J Bone Joint Surg Am. 2009;91:2622–2636.PubMedCrossRef Spence G, Hocking R, Wedge JH, Roposch A. The effect of innominate and varus-derotation osteotomy on acetabular development in developmental dysplasia of the hip. J Bone Joint Surg Am. 2009;91:2622–2636.PubMedCrossRef
15.
go back to reference Tönnis D. Nomenclature and classification of congenital hip dislocation. In: Tönnis D, ed. Congenital Dysplasia and Dislocation of the Hip in Children and Adults. Berlin, Germany: Springer-Verlag; 1987:80–83. Tönnis D. Nomenclature and classification of congenital hip dislocation. In: Tönnis D, ed. Congenital Dysplasia and Dislocation of the Hip in Children and Adults. Berlin, Germany: Springer-Verlag; 1987:80–83.
16.
go back to reference Weinstein SL. The medial approach in congenital dislocation of the hip. Isr J Med Sci. 1980;16:272–275.PubMed Weinstein SL. The medial approach in congenital dislocation of the hip. Isr J Med Sci. 1980;16:272–275.PubMed
Metadata
Title
The Presence of an Ossific Nucleus Does Not Protect Against Osteonecrosis After Treatment of Developmental Dysplasia of the Hip
Authors
Andreas Roposch, MD, MSc, FRCS
Odeh Odeh, MB, BCh
Andrea S. Doria, MD, MSc, PhD
John H. Wedge, OC, MD, FRCSC
Publication date
01-10-2011
Publisher
Springer-Verlag
Published in
Clinical Orthopaedics and Related Research® / Issue 10/2011
Print ISSN: 0009-921X
Electronic ISSN: 1528-1132
DOI
https://doi.org/10.1007/s11999-011-1801-6

Other articles of this Issue 10/2011

Clinical Orthopaedics and Related Research® 10/2011 Go to the issue

Symposium: Clinically Relevant Strategies for Treating Cartilage and Meniscal Pathology

Integration of Tissue-engineered Cartilage With Host Cartilage: An In Vitro Model

Symposium: Clinically Relevant Strategies for Treating Cartilage and Meniscal Pathology

The Classic: Cartilaginous-cup Arthroplasty in Ununited Fractures of the Neck of the Femur

Symposium: Clinically Relevant Strategies for Treating Cartilage and Meniscal Pathology

Clinically Relevant Strategies for Treating Cartilage and Meniscal Pathology: Editorial Comment

Symposium: Clinically Relevant Strategies for Treating Cartilage and Meniscal Pathology

Cell-based Meniscal Tissue Engineering: A Case for Synoviocytes