Skip to main content
Top
Published in: Clinical Orthopaedics and Related Research® 11/2010

01-11-2010 | Clinical Research

Osteolysis in Well-functioning Fixed- and Mobile-bearing TKAs in Younger Patients

Authors: Young-Hoo Kim, MD, Yoowang Choi, MD, Jun-Shik Kim, MD

Published in: Clinical Orthopaedics and Related Research® | Issue 11/2010

Login to get access

Abstract

Background

Periprosthetic osteolysis is an increasingly prevalent complication of TKA. To reduce the polyethylene wear and periprosthetic osteolysis, particularly in young patients, the design of the contemporary fixed-bearing TKAs has been modified and mobile-bearing TKAs have been introduced.

Questions/purposes

We asked whether the prevalence of osteolysis would be less in well-functioning mobile-bearing TKAs than in well-functioning contemporary fixed-bearing TKAs in young patients.

Patients and Methods

We compared 488 patients (894 knees) who received fixed-bearing knee prostheses with 445 patients (816 knees) who received mobile-bearing knee prostheses. There were 187 men and 301 women (mean age, 58.6 years; range, 33-65 years) in the fixed-bearing group and 167 men and 278 women (mean age, 55.7 years; range, 33-65 years) in the mobile-bearing group. The mean followup was 12.6 years (range, 10–17 years) in the fixed-bearing group and 12.9 years (range, 10–17 years) in the mobile-bearing group.

Results

The incidence of osteolysis was 1.6% (14 of 894 knees) in the fixed-bearing group and 2.2% (18 of 816 knees) in the mobile-bearing group at the final review. The mean postoperative Knee Society knee and function scores were 92.9 points and 83.5 points, respectively, in the fixed-bearing group and 90.7 points and 83.8 points, respectively, in the mobile-bearing group. The revision rates were 3.7% (33 of 894 knees) in the fixed-bearing group and 2.7% (22 of 816 knees) in the mobile-bearing group.

Conclusions

We found the incidence of osteolysis, rate of revision, and implant survivorship were similar between fixed-bearing and mobile-bearing TKAs in younger patients.

Level of Evidence

Level III, therapeutic study. See the guidelines for authors for a complete description of levels of evidence.
Literature
1.
go back to reference Arora J, Ogden AC. Osteolysis in a surface-cemented, primary, modular Freeman-Samuelson total knee replacement. J Bone Joint Surg Br. 2005;87:1502–1506.CrossRefPubMed Arora J, Ogden AC. Osteolysis in a surface-cemented, primary, modular Freeman-Samuelson total knee replacement. J Bone Joint Surg Br. 2005;87:1502–1506.CrossRefPubMed
2.
go back to reference Bach CM, Biedermann R, Goebel G, Mayer E, Rachbauer F. Reproducible assessment of radiolucent lines in total knee arthroplasty. Clin Orthop Relat Res. 2005;434:183–188.CrossRefPubMed Bach CM, Biedermann R, Goebel G, Mayer E, Rachbauer F. Reproducible assessment of radiolucent lines in total knee arthroplasty. Clin Orthop Relat Res. 2005;434:183–188.CrossRefPubMed
3.
go back to reference Bertin KC. Cruciate-retaining total knee arthroplasty at 5 to 7 years followup. Clin Orthop Relat Res. 2005;436:177–183.CrossRefPubMed Bertin KC. Cruciate-retaining total knee arthroplasty at 5 to 7 years followup. Clin Orthop Relat Res. 2005;436:177–183.CrossRefPubMed
4.
go back to reference Bozic KJ, Kinder J, Meneghini RM, Zurakowski D, Rosenberg AG, Galante JO. Implant survivorship and complication rates after total knee arthroplasty with a third-generation cemented system: 5 to 8 years followup. Clin Orthop Relat Res. 2005;430:117–124.CrossRefPubMed Bozic KJ, Kinder J, Meneghini RM, Zurakowski D, Rosenberg AG, Galante JO. Implant survivorship and complication rates after total knee arthroplasty with a third-generation cemented system: 5 to 8 years followup. Clin Orthop Relat Res. 2005;430:117–124.CrossRefPubMed
5.
go back to reference Buechel FF, Pappas MJ. The New Jersey Low-Contact-Stress Knee Replacement System: biomechanical rationale and review of the first 123 cemented cases. Arch Orthop Trauma Surg. 1986;105:197–204.CrossRefPubMed Buechel FF, Pappas MJ. The New Jersey Low-Contact-Stress Knee Replacement System: biomechanical rationale and review of the first 123 cemented cases. Arch Orthop Trauma Surg. 1986;105:197–204.CrossRefPubMed
6.
go back to reference Buechel FF, Pappas MJ. Long-term survivorship analysis of cruciate-sparing versus cruciate-sacrificing knee prostheses using meniscal bearings. Clin Orthop Relat Res. 1990;260:162–169.PubMed Buechel FF, Pappas MJ. Long-term survivorship analysis of cruciate-sparing versus cruciate-sacrificing knee prostheses using meniscal bearings. Clin Orthop Relat Res. 1990;260:162–169.PubMed
7.
go back to reference Cadambi A, Engh GA, Dwyer KA, Vinh TN. Osteolysis of the distal femur after total knee arthroplasty. J Arthroplasty. 1994;9:579–594.CrossRefPubMed Cadambi A, Engh GA, Dwyer KA, Vinh TN. Osteolysis of the distal femur after total knee arthroplasty. J Arthroplasty. 1994;9:579–594.CrossRefPubMed
8.
go back to reference Callaghan JJ, O’Rourke MR, Iossi MF, Liu SS, Goetz DD, Vittetoe DA, Sullivan PM, Johnston RC. Cemented rotating-platform total knee replacement: a concise follow-up, at a minimum of fifteen years, of a previous report. J Bone Joint Surg Am. 2005;87:1995–1998.CrossRefPubMed Callaghan JJ, O’Rourke MR, Iossi MF, Liu SS, Goetz DD, Vittetoe DA, Sullivan PM, Johnston RC. Cemented rotating-platform total knee replacement: a concise follow-up, at a minimum of fifteen years, of a previous report. J Bone Joint Surg Am. 2005;87:1995–1998.CrossRefPubMed
9.
go back to reference Callaghan JJ, Squire MW, Goetz DD, Sullivan PM, Johnston RC. Cemented rotating-platform total knee replacement: a nine to twelve-year follow-up study. J Bone Joint Surg Am. 2000;82:705–711.CrossRefPubMed Callaghan JJ, Squire MW, Goetz DD, Sullivan PM, Johnston RC. Cemented rotating-platform total knee replacement: a nine to twelve-year follow-up study. J Bone Joint Surg Am. 2000;82:705–711.CrossRefPubMed
10.
go back to reference Collier JP, Sperling DK, Currier JH, Sutula LC, Saum KA, Mayor MB. Impact of gamma sterilization on clinical performance of polyethylene in the knee. J Arthroplasty. 1996;11:377–389.CrossRefPubMed Collier JP, Sperling DK, Currier JH, Sutula LC, Saum KA, Mayor MB. Impact of gamma sterilization on clinical performance of polyethylene in the knee. J Arthroplasty. 1996;11:377–389.CrossRefPubMed
11.
go back to reference Collier MB, Engh CA Jr, McAuley JP, Ginn SD, Engh GA. Osteolysis after total knee arthroplasty: influence of tibial baseplate surface finish and sterilization of polyethylene insert. Findings at five to ten years postoperatively. J Bone Joint Surg Am. 2005;87:2702–2708.CrossRefPubMed Collier MB, Engh CA Jr, McAuley JP, Ginn SD, Engh GA. Osteolysis after total knee arthroplasty: influence of tibial baseplate surface finish and sterilization of polyethylene insert. Findings at five to ten years postoperatively. J Bone Joint Surg Am. 2005;87:2702–2708.CrossRefPubMed
12.
go back to reference Dalury DF, Barrett WP, Mason JB, Goldstein WM, Murphy JA, Roche MW. Midterm survival of a contemporary modular total knee replacement: a multicentre study of 1970 knees. J Bone Joint Surg Br. 2008;90:1594–1596.CrossRefPubMed Dalury DF, Barrett WP, Mason JB, Goldstein WM, Murphy JA, Roche MW. Midterm survival of a contemporary modular total knee replacement: a multicentre study of 1970 knees. J Bone Joint Surg Br. 2008;90:1594–1596.CrossRefPubMed
13.
go back to reference Diduch DR, Insall JN, Scott WN, Scuderi GR, Font-Rodriguez D. Total knee replacement in young, active patients: long-term follow-up and functional outcome. J Bone Joint Surg Am. 1997;79:575–582.PubMed Diduch DR, Insall JN, Scott WN, Scuderi GR, Font-Rodriguez D. Total knee replacement in young, active patients: long-term follow-up and functional outcome. J Bone Joint Surg Am. 1997;79:575–582.PubMed
14.
go back to reference Dixon MC, Brown RR, Parsch D, Scott RD. Modular fixed-bearing total knee arthroplasty with retention of the posterior cruciate ligament: a study of patients followed for a minimum of fifteen years. J Bone Joint Surg Am. 2005;87:598–603.CrossRefPubMed Dixon MC, Brown RR, Parsch D, Scott RD. Modular fixed-bearing total knee arthroplasty with retention of the posterior cruciate ligament: a study of patients followed for a minimum of fifteen years. J Bone Joint Surg Am. 2005;87:598–603.CrossRefPubMed
15.
go back to reference Duffy GP, Trousdale RT, Stuart MJ. Total knee arthroplasty in patients 55 years old or younger: 10- to 17-year results. Clin Orthop Relat Res. 1998;356:22–27.CrossRefPubMed Duffy GP, Trousdale RT, Stuart MJ. Total knee arthroplasty in patients 55 years old or younger: 10- to 17-year results. Clin Orthop Relat Res. 1998;356:22–27.CrossRefPubMed
16.
go back to reference Ewald FC. The Knee Society total knee arthroplasty roentgenographic evaluation and scoring system. Clin Orthop Relat Res. 1989;248:9–12.PubMed Ewald FC. The Knee Society total knee arthroplasty roentgenographic evaluation and scoring system. Clin Orthop Relat Res. 1989;248:9–12.PubMed
17.
go back to reference Ezzet KA, Garcia R, Barrack RL. Effect of component fixation method on osteolysis in total knee arthroplasty. Clin Orthop Relat Res. 1995;321:86–91.PubMed Ezzet KA, Garcia R, Barrack RL. Effect of component fixation method on osteolysis in total knee arthroplasty. Clin Orthop Relat Res. 1995;321:86–91.PubMed
18.
go back to reference Faris PM, Keating EM, Farris A, Meding JB, Ritter MA. Hybrid total knee arthroplasty: 13-year survivorship of AGC total knee systems with average 7 years followup. Clin Orthop Relat Res. 2008;466:1204–1209.CrossRefPubMed Faris PM, Keating EM, Farris A, Meding JB, Ritter MA. Hybrid total knee arthroplasty: 13-year survivorship of AGC total knee systems with average 7 years followup. Clin Orthop Relat Res. 2008;466:1204–1209.CrossRefPubMed
19.
go back to reference Gioe TJ, Glynn J, Sembrano J, Suthers K, Santos ER, Singh J. Mobile and fixed-bearing (all-polyethylene tibial component) total knee arthroplasty designs: a prospective randomized trial. J Bone Joint Surg Am. 2009;91:2104–2112.CrossRefPubMed Gioe TJ, Glynn J, Sembrano J, Suthers K, Santos ER, Singh J. Mobile and fixed-bearing (all-polyethylene tibial component) total knee arthroplasty designs: a prospective randomized trial. J Bone Joint Surg Am. 2009;91:2104–2112.CrossRefPubMed
20.
go back to reference Goodfellow JW, O’Connor J. Clinical results of the Oxford knee. Surface arthroplasty of the tibiofemoral joint with a meniscal bearing prosthesis. Clin Orthop Relat Res. 1986;205:21–42.PubMed Goodfellow JW, O’Connor J. Clinical results of the Oxford knee. Surface arthroplasty of the tibiofemoral joint with a meniscal bearing prosthesis. Clin Orthop Relat Res. 1986;205:21–42.PubMed
21.
go back to reference Huang CH, Ma HM, Liau JJ, Ho FY, Cheng CK. Osteolysis in failed total knee arthroplasty: a comparison of mobile-bearing and fixed-bearing knees. J Bone Joint Surg Am. 2002;84:2224–2229.PubMed Huang CH, Ma HM, Liau JJ, Ho FY, Cheng CK. Osteolysis in failed total knee arthroplasty: a comparison of mobile-bearing and fixed-bearing knees. J Bone Joint Surg Am. 2002;84:2224–2229.PubMed
22.
go back to reference Insall JN. Adventures in mobile-bearing knee design: a mid-life crisis. Orthopedics. 1998;21:1021–1023.PubMed Insall JN. Adventures in mobile-bearing knee design: a mid-life crisis. Orthopedics. 1998;21:1021–1023.PubMed
23.
go back to reference Insall JN, Ranawat CS, Aglietti P, Shine J. A comparison of four models of total knee-replacement prostheses. J Bone Joint Surg Am. 1976;58:754–765.PubMed Insall JN, Ranawat CS, Aglietti P, Shine J. A comparison of four models of total knee-replacement prostheses. J Bone Joint Surg Am. 1976;58:754–765.PubMed
24.
go back to reference Kaplan EL, Meier R. Nonparametric estimation from incomplete observations. J Am Statist Assoc. 1958;53:457–481.CrossRef Kaplan EL, Meier R. Nonparametric estimation from incomplete observations. J Am Statist Assoc. 1958;53:457–481.CrossRef
25.
go back to reference Kim YH, Kim JS. Prevalence of osteolysis after simultaneous bilateral fixed- and mobile-bearing total knee arthroplasties in young patients. J Arthroplasty. 2009;24:932–940.CrossRefPubMed Kim YH, Kim JS. Prevalence of osteolysis after simultaneous bilateral fixed- and mobile-bearing total knee arthroplasties in young patients. J Arthroplasty. 2009;24:932–940.CrossRefPubMed
26.
go back to reference Kim YH, Oh JH, Oh SH. Osteolysis around cementless porous-coated anatomic knee prostheses. J Bone Joint Surg Br. 1995;77:236–241.PubMed Kim YH, Oh JH, Oh SH. Osteolysis around cementless porous-coated anatomic knee prostheses. J Bone Joint Surg Br. 1995;77:236–241.PubMed
27.
go back to reference Kim YH, Yoon SH, Kim JS. The long-term results of simultaneous fixed-bearing and mobile-bearing total knee replacements performed in the same patient. J Bone Joint Surg Br. 2007;89:1317–1323.CrossRefPubMed Kim YH, Yoon SH, Kim JS. The long-term results of simultaneous fixed-bearing and mobile-bearing total knee replacements performed in the same patient. J Bone Joint Surg Br. 2007;89:1317–1323.CrossRefPubMed
28.
go back to reference Lachiewicz PF, Soileau ES. The rates of osteolysis and loosening associated with a modular posterior stabilized knee replacement: results at five to fourteen years. J Bone Joint Surg Am. 2004;86:525–530.CrossRefPubMed Lachiewicz PF, Soileau ES. The rates of osteolysis and loosening associated with a modular posterior stabilized knee replacement: results at five to fourteen years. J Bone Joint Surg Am. 2004;86:525–530.CrossRefPubMed
29.
go back to reference Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics. 1977;33:159–174.CrossRefPubMed Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics. 1977;33:159–174.CrossRefPubMed
30.
go back to reference Mikulak SA, Mahoney OM, dela Rosa MA, Schmalzried TP. Loosening and osteolysis with the press-fit condylar posterior-cruciate-substituting total knee replacement. J Bone Joint Surg Am. 2001;83:398–403.PubMed Mikulak SA, Mahoney OM, dela Rosa MA, Schmalzried TP. Loosening and osteolysis with the press-fit condylar posterior-cruciate-substituting total knee replacement. J Bone Joint Surg Am. 2001;83:398–403.PubMed
31.
go back to reference O’Rourke MR, Callaghan JJ, Goetz DD, Sullivan PM, Johnston RC. Osteolysis associated with a cemented modular posterior-cruciate-substituting total knee design: five to eight-year follow-up. J Bone Joint Surg Am. 2002;84:1362–1371.PubMed O’Rourke MR, Callaghan JJ, Goetz DD, Sullivan PM, Johnston RC. Osteolysis associated with a cemented modular posterior-cruciate-substituting total knee design: five to eight-year follow-up. J Bone Joint Surg Am. 2002;84:1362–1371.PubMed
32.
go back to reference Peters PC Jr, Engh GA, Dwyer KA, Vinh TN. Osteolysis after total knee arthroplasty without cement. J Bone Joint Surg Am. 1992;74:864–876.PubMed Peters PC Jr, Engh GA, Dwyer KA, Vinh TN. Osteolysis after total knee arthroplasty without cement. J Bone Joint Surg Am. 1992;74:864–876.PubMed
33.
go back to reference Price AJ, Rees JL, Beard D, Juszczak E, Carter S, White S, de Steiger R, Dodd CA, Gibbons M, McLardy-Smith P, Goodfellow JW, Murray DW. A mobile-bearing total knee prosthesis compared with a fixed-bearing prosthesis: a multicentre single-blind randomised controlled trial. J Bone Joint Surg Br. 2003;85:62–67.CrossRefPubMed Price AJ, Rees JL, Beard D, Juszczak E, Carter S, White S, de Steiger R, Dodd CA, Gibbons M, McLardy-Smith P, Goodfellow JW, Murray DW. A mobile-bearing total knee prosthesis compared with a fixed-bearing prosthesis: a multicentre single-blind randomised controlled trial. J Bone Joint Surg Br. 2003;85:62–67.CrossRefPubMed
34.
go back to reference Robinson EJ, Mulliken BD, Bourne RB, Rorabeck CH, Alvarez C. Catastrophic osteolysis in total knee replacement: a report of 17 cases. Clin Orthop Relat Res. 1995;321:98–105.PubMed Robinson EJ, Mulliken BD, Bourne RB, Rorabeck CH, Alvarez C. Catastrophic osteolysis in total knee replacement: a report of 17 cases. Clin Orthop Relat Res. 1995;321:98–105.PubMed
35.
go back to reference Sánchez-Sotelo J, Ordoñez JM, Prats SB. Results and complications of the low contact stress knee prosthesis. J Arthroplasty. 1999;14:815–821.CrossRefPubMed Sánchez-Sotelo J, Ordoñez JM, Prats SB. Results and complications of the low contact stress knee prosthesis. J Arthroplasty. 1999;14:815–821.CrossRefPubMed
36.
go back to reference Sorrells RB, Stiehl JB, Voorhorst PE. Midterm results of mobile-bearing total knee arthroplasty in patients younger than 65 years. Clin Orthop Relat Res. 2001;390:182–189.CrossRefPubMed Sorrells RB, Stiehl JB, Voorhorst PE. Midterm results of mobile-bearing total knee arthroplasty in patients younger than 65 years. Clin Orthop Relat Res. 2001;390:182–189.CrossRefPubMed
37.
go back to reference Tegner Y, Lysholm J. Rating systems in the evaluation of knee ligament injuries. Clin Orthop Relat Res. 1985;198:43–49.PubMed Tegner Y, Lysholm J. Rating systems in the evaluation of knee ligament injuries. Clin Orthop Relat Res. 1985;198:43–49.PubMed
38.
go back to reference Wright TM, Bartel DL. The problem of surface damage in polyethylene total knee components. Clin Orthop Relat Res. 1986;205:67–74.PubMed Wright TM, Bartel DL. The problem of surface damage in polyethylene total knee components. Clin Orthop Relat Res. 1986;205:67–74.PubMed
Metadata
Title
Osteolysis in Well-functioning Fixed- and Mobile-bearing TKAs in Younger Patients
Authors
Young-Hoo Kim, MD
Yoowang Choi, MD
Jun-Shik Kim, MD
Publication date
01-11-2010
Publisher
Springer-Verlag
Published in
Clinical Orthopaedics and Related Research® / Issue 11/2010
Print ISSN: 0009-921X
Electronic ISSN: 1528-1132
DOI
https://doi.org/10.1007/s11999-010-1336-2

Other articles of this Issue 11/2010

Clinical Orthopaedics and Related Research® 11/2010 Go to the issue

Symposium: Highlights of the ISOLS/MSTS 2009 Meeting

Does Increased Rate of Limb-sparing Surgery Affect Survival in Osteosarcoma?

Symposium: Highlights of the ISOLS/MSTS 2009 Meeting

How Long Do Endoprosthetic Reconstructions for Proximal Femoral Tumors Last?