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Clinical Orthopaedics and Related Research®

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01-07-2010 | Clinical Research

Cartilage Thickness in the Hip Measured by MRI and Stereology Before and After Periacetabular Osteotomy

Authors: Inger Mechlenburg, MSc, PhD, Jens R. Nyengaard, MD, DMSc, John Gelineck, MD, Kjeld Soballe, MD, DMSc, Anders Troelsen, MD, PhD

Published in: Clinical Orthopaedics and Related Research® | Issue 7/2010

Abstract

Background

Untreated hip dysplasia can result in a degenerative process joint and secondary osteoarthritis at an early age. While most periacetabular osteotomies (PAOs) are performed to relieve symptoms, the osteotomy is presumed to slow or prevent degeneration unless irreparable damage to the cartilage has already occurred.

Questions/purposes

We therefore determined (1) whether changes in the thickness of the cartilage in the hip occur after PAO, and (2) how many patients had an acetabular labral tear and whether labral tears are associated with thinning of the cartilage after PAO.

Patients and Methods

We prospectively followed 22 women and four men with hip dysplasia with MRI before PAO and again 1 year and 2½ years postoperatively to determine if cartilage thinning (reflecting osteoarthritis) occurred. The thickness of the femoral and acetabular cartilage was estimated with a stereologic method. Three and one-half years postoperatively, 18 of 26 patients underwent MR arthrography to investigate if they had a torn acetabular labrum.

Results

The acetabular cartilage thickness differed between 1 and 2½ years postoperatively (preoperative 1.40 mm, 1 year postoperatively 1.47 mm, and 2½ years postoperatively 1.35 mm), but was similar at all times for the femoral cartilage (preoperative 1.38 mm, 1 year postoperatively 1.43 mm, and 2½ years postoperatively 1.38 mm.) Seventeen of 18 patients had a torn labrum. The tears were located mainly superior on the acetabular rim.

Conclusion

Cartilage thickness 2½ years after surgery compared with preoperatively was unchanged indicating the osteoarthritis had not progressed during short-term followup after PAO.

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Title: Cartilage Thickness in the Hip Measured by MRI and Stereology Before and After Periacetabular Osteotomy
Authors: Inger Mechlenburg, MSc, PhD
Jens R. Nyengaard, MD, DMSc
John Gelineck, MD
Kjeld Soballe, MD, DMSc
Anders Troelsen, MD, PhD
Publication date: 01-07-2010
Publisher: Springer-Verlag
Published in: Clinical Orthopaedics and Related Research® / Issue 7/2010
Print ISSN: 0009-921X
Electronic ISSN: 1528-1132
DOI: https://doi.org/10.1007/s11999-010-1310-z

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Cartilage Thickness in the Hip Measured by MRI and Stereology Before and After Periacetabular Osteotomy

Abstract

Background

Questions/purposes

Patients and Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Questions/purposes

Patients and Methods

Results

Conclusion

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