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Published in: Current Urology Reports 10/2021

01-10-2021 | Septicemia | Endourology (P Mucksavage, Section Editor)

Gender Differences in Kidney Stone Disease (KSD): Findings from a Systematic Review

Authors: Kathryn Gillams, Patrick Juliebø-Jones, Siri Øvereng Juliebø, Bhaskar K. Somani

Published in: Current Urology Reports | Issue 10/2021

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Abstract

Purpose of Review

The prevalence of kidney stones is rising and historically carries a preponderance for males. However, recent evidence has questioned whether this gender gap is closing. The aim of this systematic review was to examine this further as well as evaluate possible underlying causes.

Recent Findings

Recent evidence confirms the disparity in kidney stone disease between genders is closing. In the modern era, the rise in prevalence among females has been greater, especially in adolescence. Quality of life is also more adversely affected by kidney stone events among females who are also more likely to develop sepsis after endourological surgery. Males, however, are more likely to present with stone events during periods of high ambient temperatures

Summary

Recent literature demonstrates a temporal change in the disease burden of KSD among men and women. The latter, especially adolescent females, are more likely to develop KSD in their lifetime compared to previous eras. Determining causation is complex and continued research is warranted.
Literature
3.
go back to reference Antonelli JA, Maalouf NM, Pearle MS, Lotan Y. Use of the national health and nutrition examination survey to calculate the impact of obesity and diabetes on cost and prevalence of urolithiasis in 2030. Eur Urol. 2014;66:724–9.CrossRef Antonelli JA, Maalouf NM, Pearle MS, Lotan Y. Use of the national health and nutrition examination survey to calculate the impact of obesity and diabetes on cost and prevalence of urolithiasis in 2030. Eur Urol. 2014;66:724–9.CrossRef
6.
go back to reference Jones P, Karim SS, Gamage KN et al. Do lifestyle factors including smoking, alcohol, and exercise impact your risk of developing kidney stone disease? Outcomes of a systematic review. J Endourol. 2020; https://doi.org/10.1089/end.2020.0378. Epub ahead of print. PMID: 32808537. Jones P, Karim SS, Gamage KN et al. Do lifestyle factors including smoking, alcohol, and exercise impact your risk of developing kidney stone disease? Outcomes of a systematic review. J Endourol. 2020; https://​doi.​org/​10.​1089/​end.​2020.​0378. Epub ahead of print. PMID: 32808537.
9.
go back to reference Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P). elaboration and explanation. BMJ. 2016;21;354:i4086. https://doi.org/10.1136/bmj.i4086. Erratum for: BMJ. 2015 Jan 02;02; 02;350:g7647. PMID: 27444514. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P). elaboration and explanation. BMJ. 2016;21;354:i4086. https://​doi.​org/​10.​1136/​bmj.​i4086. Erratum for: BMJ. 2015 Jan 02;02; 02;350:g7647. PMID: 27444514.
10.
go back to reference Abufaraj M, Xu T, Cao C, Waldhoer T, Seitz C, D'andrea D, Siyam A, Tarawneh R, Fajkovic H, Schernhammer E, Yang L, Shariat SF. Prevalence and trends in kidney stone among adults in the USA: analyses of National Health and Nutrition Examination Survey 2007–2018 Data. Eur Urol Focus. 2020;S2405–4569(20)30224–8. https://doi.org/10.1016/j.euf.2020.08.011. Epub ahead of print. PMID: 32900675. Abufaraj M, Xu T, Cao C, Waldhoer T, Seitz C, D'andrea D, Siyam A, Tarawneh R, Fajkovic H, Schernhammer E, Yang L, Shariat SF. Prevalence and trends in kidney stone among adults in the USA: analyses of National Health and Nutrition Examination Survey 2007–2018 Data. Eur Urol Focus. 2020;S2405–4569(20)30224–8. https://​doi.​org/​10.​1016/​j.​euf.​2020.​08.​011. Epub ahead of print. PMID: 32900675.
13.
15.
go back to reference Kittanamongkolchai W, Vaughan LE, Enders FT, Dhondup T, Mehta RA, Krambeck AE, McCollough CH, Vrtiska TJ, Lieske JC, Rule AD. The changing incidence and presentation of urinary stones over 3 decades. Mayo Clin Proc. 2018;93(3):291–299. https://doi.org/10.1016/j.mayocp.2017.11.018. Epub 2018 Feb 14. PMID: 29452705; PMCID: PMC5849397. Kittanamongkolchai W, Vaughan LE, Enders FT, Dhondup T, Mehta RA, Krambeck AE, McCollough CH, Vrtiska TJ, Lieske JC, Rule AD. The changing incidence and presentation of urinary stones over 3 decades. Mayo Clin Proc. 2018;93(3):291–299. https://​doi.​org/​10.​1016/​j.​mayocp.​2017.​11.​018. Epub 2018 Feb 14. PMID: 29452705; PMCID: PMC5849397.
16.
22.
25.
go back to reference Rathod A, Bonny O, Guessous I, Suter PM, Conen D, Erne P et al. Association of urinary calcium excretion with serum calcium and vitamin D levels. Clin J Am Soc Nephrol. 2015;10(3):452–62.CrossRef Rathod A, Bonny O, Guessous I, Suter PM, Conen D, Erne P et al. Association of urinary calcium excretion with serum calcium and vitamin D levels. Clin J Am Soc Nephrol. 2015;10(3):452–62.CrossRef
26.
go back to reference Xiao Y, Wei L, Xiong X, Yang Y, Li L, Yang M, Deng F, Sun L. Sex differences in kidney stone disease in Chinese patients with type 2 diabetes mellitus. Kidney Dis (Basel). 2020;6(3):195–203. https://doi.org/10.1159/000506053. Epub 2020 Feb 28. PMID: 32523961; PMCID: PMC7265720. Xiao Y, Wei L, Xiong X, Yang Y, Li L, Yang M, Deng F, Sun L. Sex differences in kidney stone disease in Chinese patients with type 2 diabetes mellitus. Kidney Dis (Basel). 2020;6(3):195–203. https://​doi.​org/​10.​1159/​000506053. Epub 2020 Feb 28. PMID: 32523961; PMCID: PMC7265720.
27.
go back to reference Kravdal G, Helgø D, Moe MK. Kidney stone compositions and frequencies in a Norwegian population. Scand J Urol. 2019;53(2–3):139–44.CrossRef Kravdal G, Helgø D, Moe MK. Kidney stone compositions and frequencies in a Norwegian population. Scand J Urol. 2019;53(2–3):139–44.CrossRef
29.
go back to reference Wood K, Boyd C, Whitaker D, Ashorobi O, Poore W, Gower B, Assimos DG. Impact of Demographic factors and systemic disease on urinary stone risk parameters amongst stone formers. Rev Urol. 2019;21(4):158–165. PMID: 32071564; PMCID: PMC7020277. Wood K, Boyd C, Whitaker D, Ashorobi O, Poore W, Gower B, Assimos DG. Impact of Demographic factors and systemic disease on urinary stone risk parameters amongst stone formers. Rev Urol. 2019;21(4):158–165. PMID: 32071564; PMCID: PMC7020277.
33.
go back to reference Lorenzo Soriano L, Ordaz Jurado DG, Pérez Ardavín J, Budía Alba A, Bahílo Mateu P, Trassierra Villa M, López Acón D. Predictive factors of infectious complications in the postoperative of percutaneous nephrolithotomy. Actas Urol Esp. 2019;43(3):131–136. English, Spanish. https://doi.org/10.1016/j.acuro.2018.05.009. Epub 2018 Nov 8. PMID: 30415829. Lorenzo Soriano L, Ordaz Jurado DG, Pérez Ardavín J, Budía Alba A, Bahílo Mateu P, Trassierra Villa M, López Acón D. Predictive factors of infectious complications in the postoperative of percutaneous nephrolithotomy. Actas Urol Esp. 2019;43(3):131–136. English, Spanish. https://​doi.​org/​10.​1016/​j.​acuro.​2018.​05.​009. Epub 2018 Nov 8. PMID: 30415829.
34.
go back to reference Nevo A, Mano R, Baniel J, Lifshitz DA. Ureteric stent dwelling time: a risk factor for postureteroscopy sepsis. BJU Int. 2017;120:117–22.CrossRef Nevo A, Mano R, Baniel J, Lifshitz DA. Ureteric stent dwelling time: a risk factor for postureteroscopy sepsis. BJU Int. 2017;120:117–22.CrossRef
35.
go back to reference Díaz Pérez D, Laso García I, Sánchez Guerrero C, Fernández Alcalde Á, Ruiz Hernández M, Brasero Burgos J, Lorca Álvaro J, Duque Ruiz G, Arias Funez F, Burgos Revilla FJ. Urinary sepsis after endourological ureterorenoscopy for the treatment of lithiasis. Actas Urol Esp. 2019;43(6):293–299. English, Spanish. https://doi.org/10.1016/j.acuro.2019.02.001. Epub 2019 May 2. PMID: 31056221. Díaz Pérez D, Laso García I, Sánchez Guerrero C, Fernández Alcalde Á, Ruiz Hernández M, Brasero Burgos J, Lorca Álvaro J, Duque Ruiz G, Arias Funez F, Burgos Revilla FJ. Urinary sepsis after endourological ureterorenoscopy for the treatment of lithiasis. Actas Urol Esp. 2019;43(6):293–299. English, Spanish. https://​doi.​org/​10.​1016/​j.​acuro.​2019.​02.​001. Epub 2019 May 2. PMID: 31056221.
36.
go back to reference Baboudjian M, Gondran-Tellier B, Abdallah R, Sichez PC, Akiki A, Gaillet S, Delaporte V, Karsenty G, Lechevallier E, Boissier R. Predictive risk factors of urinary tract infection following flexible ureteroscopy despite preoperative precautions to avoid infectious complications. World J Urol. 2020;38(5):1253–9. https://doi.org/10.1007/s00345-019-02891-8 (Epub 2019 Jul 29 PMID: 31359106).CrossRefPubMed Baboudjian M, Gondran-Tellier B, Abdallah R, Sichez PC, Akiki A, Gaillet S, Delaporte V, Karsenty G, Lechevallier E, Boissier R. Predictive risk factors of urinary tract infection following flexible ureteroscopy despite preoperative precautions to avoid infectious complications. World J Urol. 2020;38(5):1253–9. https://​doi.​org/​10.​1007/​s00345-019-02891-8 (Epub 2019 Jul 29 PMID: 31359106).CrossRefPubMed
42.
go back to reference Tasian GE, Ross ME, Song L, Sas DJ, Keren R, Denburg MR, Chu DI, Copelovitch L, Saigal CS, Furth SL. Annual incidence of nephrolithiasis among children and adults in South Carolina from 1997 to 2012. Clin J Am Soc Nephrol. 2016;11(3):488–96. https://doi.org/10.2215/CJN.07610715. Epub 2016 Jan 14. PMID: 26769765; PMCID: PMC4791823. Tasian GE, Ross ME, Song L, Sas DJ, Keren R, Denburg MR, Chu DI, Copelovitch L, Saigal CS, Furth SL. Annual incidence of nephrolithiasis among children and adults in South Carolina from 1997 to 2012. Clin J Am Soc Nephrol. 2016;11(3):488–96. https://​doi.​org/​10.​2215/​CJN.​07610715. Epub 2016 Jan 14. PMID: 26769765; PMCID: PMC4791823.
45.
go back to reference Vicedo-Cabrera AM, Goldfarb DS, Kopp RE, Song L, Tasian GE. Sex differences in the temperature dependence of kidney stone presentations: a population-based aggregated case-crossover study. Urolithiasis. 2020;48(1):37–46. https://doi.org/10.1007/s00240-019-01129-x. Epub 2019 Mar 21. PMID: 30900001; PMCID: PMC7357996. Vicedo-Cabrera AM, Goldfarb DS, Kopp RE, Song L, Tasian GE. Sex differences in the temperature dependence of kidney stone presentations: a population-based aggregated case-crossover study. Urolithiasis. 2020;48(1):37–46. https://​doi.​org/​10.​1007/​s00240-019-01129-x. Epub 2019 Mar 21. PMID: 30900001; PMCID: PMC7357996.
48.
go back to reference Fukuhara H, Ichiyanagi O, Kakizaki H, Naito S, Tsuchiya N. Clinical relevance of seasonal changes in the prevalence of ureterolithiasis in the diagnosis of renal colic. Urolithiasis. 2016;44(6):529–537. https://doi.org/10.1007/s00240-016-0896-3. Epub 2016 Jun 17. PMID: 27314408; PMCID: PMC5063892. Fukuhara H, Ichiyanagi O, Kakizaki H, Naito S, Tsuchiya N. Clinical relevance of seasonal changes in the prevalence of ureterolithiasis in the diagnosis of renal colic. Urolithiasis. 2016;44(6):529–537. https://​doi.​org/​10.​1007/​s00240-016-0896-3. Epub 2016 Jun 17. PMID: 27314408; PMCID: PMC5063892.
50.
go back to reference Tavasoli S, Taheri M, Khoshdel A, Basiri A. Association of body mass index, waist circumference, and waist-stature ratio with urine composition in patients with urolithiasis. Iran J Kidney Dis. 2017;11(5):371–8 (PMID: 29038393).PubMed Tavasoli S, Taheri M, Khoshdel A, Basiri A. Association of body mass index, waist circumference, and waist-stature ratio with urine composition in patients with urolithiasis. Iran J Kidney Dis. 2017;11(5):371–8 (PMID: 29038393).PubMed
Metadata
Title
Gender Differences in Kidney Stone Disease (KSD): Findings from a Systematic Review
Authors
Kathryn Gillams
Patrick Juliebø-Jones
Siri Øvereng Juliebø
Bhaskar K. Somani
Publication date
01-10-2021
Publisher
Springer US
Published in
Current Urology Reports / Issue 10/2021
Print ISSN: 1527-2737
Electronic ISSN: 1534-6285
DOI
https://doi.org/10.1007/s11934-021-01066-6

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