Top

Published in:

01-06-2013 | Prostate Cancer (D Parekh, Section Editor)

MRI-Guided Biopsy for Prostate Cancer Detection: A Systematic Review of Current Clinical Results

Authors: Christiaan G. Overduin, Jurgen J. Fütterer, Jelle O. Barentsz

Published in: Current Urology Reports | Issue 3/2013

Abstract

In-bore magnetic resonance-guided biopsy (MRGB) has been increasingly used in clinical practice to detect prostate cancer (PCa). This review summarizes the current clinical results of this biopsy method. A systematic literature search was performed in the PubMed and Embase databases. Of 2,035 identified records, 49 required full review. In all, ten unique studies reporting clinical results of MRGB could be included. Reported PCa detection rates ranged from 8 to 59 % (median 42 %). The majority of tumors detected by MRGB were clinically significant (81–93 %). Most frequent complications of MRGB are transient hematuria (1–24 %) and short-term perirectal bleeding (11–17 %). Major complications are rare. Based on the reviewed literature, MRGB can be regarded an accurate and safe diagnostic tool to detect clinically significant PCa. However, as general availability is limited, this procedure should be reserved for specific patients. Appropriate indications will have to be determined.

Siegel R, Ward E, Brawley O, et al. Cancer Statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin. 2011;61:212–36.PubMedCrossRef

Roehl KA, Antenor JA, Catalona WJ. Serial biopsy results in prostate cancer screening study. J Urol. 2002;167(6):2435–9.PubMedCrossRef

Djavan B, Milani S, Remzi M. Prostate biopsy: who, how and when. An update. Can J Urol. 2005;12:44–8.PubMed

Lujan M, Paez A, Santonja C, et al. Prostate cancer detection and tumor characteristics in men with multiple biopsy sessions. Prostate Cancer Prostatic Dis. 2004;7:238–42.PubMedCrossRef

Tanimoto A, Nakashima J, Kohno H, et al. Prostate cancer screening: the clinical value of diffusion-weighted imaging and dynamic MR imaging in combination with T2-weighted imaging. J Magn Reson Imaging. 2007;25:146–52.PubMedCrossRef

Delongchamps NB, Rouanne M, Flam T, et al. Multiparametric magnetic resonance imaging for the detection and localization of prostate cancer: combination of T2-weighted, dynamic contrast-enhanced and diffusion-weighted imaging. BJU Int. 2011;107:1411–8.PubMedCrossRef

D’Amico AV, Tempany CM, Cormack RA, et al. Transperineal magnetic resonance image-guided prostate biopsy. J Urol. 2000;164(2):385–7.PubMedCrossRef

Cormack RA, D’Amico AV, Hata N, et al. Feasibility of transperineal prostate biopsy under interventional magnetic resonance guidance. Urology. 2000;56:663–4.PubMedCrossRef

Beyersdorff D, Winkel A, Hamm B, et al. MR imaging-guided prostate biopsy with a closed MR unit at 1.5T: initial results. Radiology. 2005;234:576–81.PubMedCrossRef

10.

•• Pondman KM, Fütterer JJ, ten Haken B, et al. MR-guided biopsy of the prostate: an overview of techniques and a systematic review. Eur Urol. 2008;54(3):517–27. Extensive overview of current strategies to perform MRGB. The authors conclude that MRGB is a promising tool to use in patients with previous negative TRUSGB. PubMedCrossRef

11.

Zangos S, Eichler K, Engelmann K, et al. MR-guided transgluteal biopsies with an open low-field system in patients with clinically suspected prostate cancer: technique and preliminary results. Eur Radiol. 2005;15:174–82.PubMedCrossRef

12.

Anastasiadis AG, Lichy MP, Nagale U, et al. MRI-guided biopsy of the prostate increases diagnostic performance in men with elevated or increasing PSA levels after previous negative TRUS biopsies. Eur Urol. 2006;50:738–49.PubMedCrossRef

13.

Singh AK, Krieger A, Lattouf JB, et al. Patient selection determines the prostate cancer yield of dynamic contrast-enhanced magnetic resonance imaging-guided transrectal biopsies in a closed 3-Tesla scanner. BJU Int. 2007;101:181–5.PubMed

14.

Hambrock T, Somford DM, Hoeks C, et al. Magnetic resonance imaging-guided prostate biopsy in men with repeat negative biopsies and increased prostate specific antigen. J Urol. 2010;183(2):520–7.PubMedCrossRef

15.

Franiel T, Stephan C, Erbersdobler A, et al. Areas suspicious for prostate cancer: MR-guided biopsy in patients with at least one transrectal US-guided biopsy with a negative finding – multiparametric MR imaging for detection and biopsy planning. Radiology. 2011;259(1):162–72.PubMedCrossRef

16.

Engehausen DG, Engelhard K, Schwab SA, et al. Magnetic resonance image-guided biopsies with a high detection rate of prostate cancer. Sci World J. 2012, Article ID 975971.

17.

•• Hoeks CMA, Schouten MG, Bomers JGR, et al. Three-Tesla magnetic resonance-guided prostate biopsy in men with increased prostate-specific antigen and repeated, negative, random, systematic, transrectal ultrasound biopsies: detection of clinically significant prostate cancers. Eur Urol. 2012;62:902–9. Largest study describing clinical results of MRGB in patients with previous negative TRUSGB. In a cohort of 265 patients, the authors show MRGB to achieve high diagnostic performance at acceptable complication rates. PubMedCrossRef

18.

Roethke M, Anastasiadis AG, Lichy M, et al. MRI-guided prostate biopsy detects clinically significant cancer: analysis of a cohort of 100 patients after previous negative TRUS biopsy. World J Urol. 2012;30:213–8.PubMedCrossRef

19.

Schwab SA, Kuefner MA, Adamietz B et al. MRI-guided core biopsy of the prostate in the supine position -- introduction of a simplified technique using large-bore magnet systems. Eur Radiol 2012, Epub ahead of print.

20.

Djavan B, Remzi M, Ghawidel K, et al. Diagnosis of prostate cancer: the clinical use of transrectal ultrasound and biopsy. EAU Updat Ser. 2003;1:9–15.CrossRef

21.

Pinkstaff DM, Igel TC, Petrou SP, et al. Systematic transperineal ultrasound-guided template biopsy of the prostate: three-year experience. Urology. 2005;65:735–9.PubMedCrossRef

22.

Norberg M, Egevad L, Holmberg L, et al. The sextant protocol for ultrasound-guided core biopsies of the prostate underestimates the presence of cancer. Urology. 1997;50(4):562–6.PubMedCrossRef

23.

Fleshner NE, O’Sullivan M, Fair WR. Prevalence and predictors of a positive repeat transrectal ultrasound guided needle biopsy of the prostate. J Urol. 1997;158:505–8.PubMedCrossRef

24.

Djavan B, Waldert M, Zlotta A, et al. Safety and morbidity of first and repeat transrectal ultrasound guided prostate needle biopsies: results of a prospective European prostate cancer detection study. J Urol. 2001;166:856–60.PubMedCrossRef

25.

Raaijmakers R, Kirkels WJ, Roobol MJ, et al. Complication rates and risk factors of 5802 transrectal ultrasound-guided sextant biopsies of the prostate within a population-based screening program. Urology. 2002;60(5):826–30.PubMedCrossRef

26.

Sakai I, Harada K, Hara I, et al. A comparison of the biological features between prostate cancers arising in the transition and peripheral zones. BJU Int. 2005;96:528–32.PubMedCrossRef

27.

Cheng L, Jones TD, Pan C, et al. Anatomic distribution and pathologic characterization of small-volume prostate cancer (<0.5 ml) in whole-mount prostatectomy specimens. Mod Pathol. 2005;18:1022–6.PubMedCrossRef

28.

Lawrentschuk N, Haider MA, Daljeet N, et al. Prostatic evasive anterior tumours: the role of magnetic resonance imaging. BJU Int. 2010;105(9):1231–6.PubMedCrossRef

29.

Hambrock T, Hoeks CM, Hulsbergen-van de Kaa C, et al. Prospective assessment of prostate cancer aggressiveness using 3-T diffusion-weighted magnetic resonance imaging–guided biopsies versus a systematic 10-core transrectal ultrasound prostate biopsy cohort. Eur Urol. 2012;61(1):177–84.PubMedCrossRef

30.

Paulson DF. Impact of radical prostatectomy in the management of clinically localized disease. J Urol. 1994;152(5):1826–30.PubMed

31.

Steinberg DM, Sauvageot J, Piantadosi S, et al. Correlation of prostate needle biopsy and radical prostatectomy Gleason grade in academic and community settings. Am J Surg Pathol. 1997;21(5):566–76.PubMedCrossRef

32.

Coogan CL, Latchamsetty KC, Greenfield J, et al. Increasing the number of biopsy cores improves the concordance of biopsy Gleason score to prostatectomy Gleason score. BJU Int. 2005;96(3):324–7.PubMedCrossRef

33.

Irani J, Fournier F, Bon D, et al. Patient tolerance of transrectal ultrasound-guided biopsy of the prostate. Br J Urol. 1997;79:608–10.PubMedCrossRef

34.

Zangos S, Melzer A, Eichler K, et al. MR-compatible assistance system for biopsy in a high-field-strength system: initial results in patients with suspicious prostate lesions. Radiology. 2011;259:903–10.PubMedCrossRef

35.

Yakar D, Schouten MG, Bosboom DG, et al. Feasibility of a pneumatically actuated MR-compatible robot for transrectal prostate biopsy guidance. Radiology. 2011;260:241–7.PubMedCrossRef

36.

Fütterer JJ, Barentsz JO. MRI-guided and robotic-assisted prostate biopsy. Curr Opin Urol. 2012;22:316–9.PubMedCrossRef

37.

Singh AK, Kruecker J, Xu S, et al. Initial clinical experience with real-time transrectal ultrasonography-magnetic resonance imaging fusion-guided prostate biopsy. BJU Int. 2008;101(7):841–5.PubMedCrossRef

38.

Ukimura O, Hirahara N, Fujihara A, et al. Technique for a hybrid system of real-time transrectal ultrasound with preoperative magnetic resonance imaging in the guidance of targeted prostate biopsy. Int J Urol. 2010;17:890–3.PubMedCrossRef

39.

•• Hadaschik BA, Kuru TH, Tulea C, et al. A novel stereotactic prostate biopsy system integrating pre-interventional magnetic resonance imaging and live ultrasound fusion. J Urol. 2011;186(6):2214–20. MR/TRUS-fusion guided biopsy may be a promising alternative to increase the general availability of targeted biopsy strategies. In their study, the authors report initial clinical experience using this technique in a transperineal approach, with promising results. PubMedCrossRef

Title: MRI-Guided Biopsy for Prostate Cancer Detection: A Systematic Review of Current Clinical Results
Authors: Christiaan G. Overduin
Jurgen J. Fütterer
Jelle O. Barentsz
Publication date: 01-06-2013
Publisher: Current Science Inc.
Published in: Current Urology Reports / Issue 3/2013
Print ISSN: 1527-2737
Electronic ISSN: 1534-6285
DOI: https://doi.org/10.1007/s11934-013-0323-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

MRI-Guided Biopsy for Prostate Cancer Detection: A Systematic Review of Current Clinical Results

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 3/2013

Practical Use of the New American Urological Association Adult Urodynamics Guidelines

Response to the U.S. Preventative Services Task Force Decision on Prostate Cancer Screening

Intermittent Versus Continuous Androgen Deprivation Therapy in Advanced Prostate Cancer

Risk-Based Prostate Cancer Screening: Who and How?

Management of Castrate Resistant Prostate Cancer—Recent Advances and Optimal Sequence of Treatments

Advances in Minimally Invasive Repair of Vesicovaginal Fistulas