Skip to main content
Top
Published in: Current Urology Reports 2/2011

01-04-2011

Laparoscopic and Image-guided Radiofrequency Ablation of Renal Tumors: Patient Selection and Outcomes

Authors: Scott M. Castle, Vladislav Gorbatiy, Obi Ekwenna, Raymond J. Leveillee

Published in: Current Urology Reports | Issue 2/2011

Login to get access

Abstract

Multiple modalities exist for the management of small renal tumors, including active surveillance, extirpation (radical nephrectomy and partial nephrectomy), and ablative therapies. Radiofrequency ablation (RFA) is an alternative to extirpative surgery for renal tumors. This article presents the current literature on RFA for renal tumors. We reviewed 28 RFA series in the English literature from 2003 to 2010 to assess patient selection, biopsy, renal outcomes, and oncologic outcomes.
Literature
1.
2.
go back to reference Luciani LG, Cestari R, Tallarigo C (2000) Incidental renal cell carcinoma-age and stage characterization and clinical implications: study of 1092 patients (1982–1997). Urology 56: 58–62PubMedCrossRef Luciani LG, Cestari R, Tallarigo C (2000) Incidental renal cell carcinoma-age and stage characterization and clinical implications: study of 1092 patients (1982–1997). Urology 56: 58–62PubMedCrossRef
3.
go back to reference Jayson M, Sanders H (1998) Increased incidence of serendipitously discovered renal cell carcinoma Urology 51: 203–205PubMedCrossRef Jayson M, Sanders H (1998) Increased incidence of serendipitously discovered renal cell carcinoma Urology 51: 203–205PubMedCrossRef
4.
go back to reference •• Campbell SC, Novick AC, Belldegrun A, et al. (2009) Guideline for management of the clinical T1 renal mass J Urol 182: 1271–1279. This reference is the AUA guidelines for T1 renal masses, and highlights the standards for treating T1 renal masses and the role of thermal ablation. •• Campbell SC, Novick AC, Belldegrun A, et al. (2009) Guideline for management of the clinical T1 renal mass J Urol 182: 1271–1279. This reference is the AUA guidelines for T1 renal masses, and highlights the standards for treating T1 renal masses and the role of thermal ablation.
5.
go back to reference Haemmerich D, Laeseke PF (2005) Thermal tumour ablation: devices, clinical applications and future directions. Int J Hyperthermia 21: 755–760PubMedCrossRef Haemmerich D, Laeseke PF (2005) Thermal tumour ablation: devices, clinical applications and future directions. Int J Hyperthermia 21: 755–760PubMedCrossRef
6.
go back to reference Carey RI, Leveillee RJ (2007) First prize: direct real-time temperature monitoring for laparoscopic and CT-guided radiofrequency ablation of renal tumors between 3 and 5 cm. J Endourol 21: 807–813PubMedCrossRef Carey RI, Leveillee RJ (2007) First prize: direct real-time temperature monitoring for laparoscopic and CT-guided radiofrequency ablation of renal tumors between 3 and 5 cm. J Endourol 21: 807–813PubMedCrossRef
7.
go back to reference Matin SF, Ahrar K (2008) Nephron-sparing probe ablative therapy: long-term outcomes Curr Opin Urol 18: 150–156PubMedCrossRef Matin SF, Ahrar K (2008) Nephron-sparing probe ablative therapy: long-term outcomes Curr Opin Urol 18: 150–156PubMedCrossRef
8.
go back to reference Bird VG, Carey RI, Ayyathurai R, et al. (2009) Management of renal masses with laparoscopic-guided radiofrequency ablation versus laparoscopic partial nephrectomy J Endourol 23: 81–88PubMedCrossRef Bird VG, Carey RI, Ayyathurai R, et al. (2009) Management of renal masses with laparoscopic-guided radiofrequency ablation versus laparoscopic partial nephrectomy J Endourol 23: 81–88PubMedCrossRef
9.
go back to reference Wingo MS, Leveillee RJ (2008) Central and deep renal tumors can be effectively ablated: radiofrequency ablation outcomes with fiberoptic peripheral temperature monitoring J Endourol 22: 1261–1267PubMedCrossRef Wingo MS, Leveillee RJ (2008) Central and deep renal tumors can be effectively ablated: radiofrequency ablation outcomes with fiberoptic peripheral temperature monitoring J Endourol 22: 1261–1267PubMedCrossRef
10.
go back to reference •• Tracy CR, Raman JD, Donnally C, et al. (2010) Durable oncologic outcomes after radiofrequency ablation: experience from treating 243 small renal masses over 7.5 years Cancer 116: 3135–3142. This reference represents the largest reported series on oncologic outcomes of RFA. •• Tracy CR, Raman JD, Donnally C, et al. (2010) Durable oncologic outcomes after radiofrequency ablation: experience from treating 243 small renal masses over 7.5 years Cancer 116: 3135–3142. This reference represents the largest reported series on oncologic outcomes of RFA.
11.
go back to reference Leveridge MJ, Mattar K, Kachura J, et al. (2010) Assessing outcomes in probe ablative therapies for small renal masses J Endourol 24: 759–764PubMedCrossRef Leveridge MJ, Mattar K, Kachura J, et al. (2010) Assessing outcomes in probe ablative therapies for small renal masses J Endourol 24: 759–764PubMedCrossRef
12.
go back to reference Weight CJ, Kaouk JH, Hegarty NJ, et al. (2008) Correlation of radiographic imaging and histopathology following cryoablation and radio frequency ablation for renal tumors J Urol 179: 1277–1281; discussion 1281–1273PubMedCrossRef Weight CJ, Kaouk JH, Hegarty NJ, et al. (2008) Correlation of radiographic imaging and histopathology following cryoablation and radio frequency ablation for renal tumors J Urol 179: 1277–1281; discussion 1281–1273PubMedCrossRef
13.
go back to reference Nguyen CT, Lane BR, Kaouk JH, et al. (2008) Surgical salvage of renal cell carcinoma recurrence after thermal ablative therapy. J Urol 180: 104–109; discussion 109PubMedCrossRef Nguyen CT, Lane BR, Kaouk JH, et al. (2008) Surgical salvage of renal cell carcinoma recurrence after thermal ablative therapy. J Urol 180: 104–109; discussion 109PubMedCrossRef
14.
go back to reference Kowalczyk KJ, Hooper HB, Linehan WM, et al. (2009) Partial nephrectomy after previous radio frequency ablation: the National Cancer Institute experience J Urol 182: 2158–2163PubMedCrossRef Kowalczyk KJ, Hooper HB, Linehan WM, et al. (2009) Partial nephrectomy after previous radio frequency ablation: the National Cancer Institute experience J Urol 182: 2158–2163PubMedCrossRef
15.
go back to reference Simon CJ, Dupuy DE, Mayo-Smith WW (2005) Microwave ablation: principles and applications. Radiographics 25 Suppl 1: S69–83PubMedCrossRef Simon CJ, Dupuy DE, Mayo-Smith WW (2005) Microwave ablation: principles and applications. Radiographics 25 Suppl 1: S69–83PubMedCrossRef
16.
go back to reference Matin SF, Ahrar K, Cadeddu JA, et al. (2006) Residual and recurrent disease following renal energy ablative therapy: a multi-institutional study J Urol 176: 1973–1977PubMedCrossRef Matin SF, Ahrar K, Cadeddu JA, et al. (2006) Residual and recurrent disease following renal energy ablative therapy: a multi-institutional study J Urol 176: 1973–1977PubMedCrossRef
17.
go back to reference Stern JM, Svatek R, Park S, et al. (2007) Intermediate comparison of partial nephrectomy and radiofrequency ablation for clinical T1a renal tumours. BJU Int 100: 287-290PubMedCrossRef Stern JM, Svatek R, Park S, et al. (2007) Intermediate comparison of partial nephrectomy and radiofrequency ablation for clinical T1a renal tumours. BJU Int 100: 287-290PubMedCrossRef
18.
go back to reference •• Raman JD, Raj GV, Lucas SM, et al. (2010) Renal functional outcomes for tumours in a solitary kidney managed by ablative or extirpative techniques BJU Int 105: 496–500. Preservation of renal function is a major feature of ablative techniques compared to extirpative ones. This series, which examines patients with solitary kidneys treated with both techniques, demonstrates an improved functional outcome for RFA patients. •• Raman JD, Raj GV, Lucas SM, et al. (2010) Renal functional outcomes for tumours in a solitary kidney managed by ablative or extirpative techniques BJU Int 105: 496–500. Preservation of renal function is a major feature of ablative techniques compared to extirpative ones. This series, which examines patients with solitary kidneys treated with both techniques, demonstrates an improved functional outcome for RFA patients.
19.
go back to reference Lucas SM, Stern JM, Adibi M, et al. (2008) Renal function outcomes in patients treated for renal masses smaller than 4 cm by ablative and extirpative techniques J Urol 179: 75–79; discussion 79-80PubMedCrossRef Lucas SM, Stern JM, Adibi M, et al. (2008) Renal function outcomes in patients treated for renal masses smaller than 4 cm by ablative and extirpative techniques J Urol 179: 75–79; discussion 79-80PubMedCrossRef
20.
go back to reference Ginat DT, Saad W, Davies M, et al. (2009) Bowel displacement for CT-guided tumor radiofrequency ablation: techniques and anatomic considerations J Endourol 23: 1259–1264PubMedCrossRef Ginat DT, Saad W, Davies M, et al. (2009) Bowel displacement for CT-guided tumor radiofrequency ablation: techniques and anatomic considerations J Endourol 23: 1259–1264PubMedCrossRef
21.
go back to reference Kyle CC, Wingo MS, Carey RI, et al. (2008) Diagnostic yield of renal biopsy immediately prior to laparoscopic radiofrequency ablation: a multicenter study J Endourol 22: 2291–2293PubMedCrossRef Kyle CC, Wingo MS, Carey RI, et al. (2008) Diagnostic yield of renal biopsy immediately prior to laparoscopic radiofrequency ablation: a multicenter study J Endourol 22: 2291–2293PubMedCrossRef
22.
go back to reference Takaki H, Yamakado K, Soga N, et al. (2010) Midterm results of radiofrequency ablation versus nephrectomy for T1a renal cell carcinoma. Jpn J Radiol 28: 460–468PubMedCrossRef Takaki H, Yamakado K, Soga N, et al. (2010) Midterm results of radiofrequency ablation versus nephrectomy for T1a renal cell carcinoma. Jpn J Radiol 28: 460–468PubMedCrossRef
23.
go back to reference Bird VG, Kanagarajah P, Morillo G, et al. (2010) Differentiation of oncocytoma and renal cell carcinoma in small renal masses (<4 cm): the role of 4-phase computerized tomography World J Urol Bird VG, Kanagarajah P, Morillo G, et al. (2010) Differentiation of oncocytoma and renal cell carcinoma in small renal masses (<4 cm): the role of 4-phase computerized tomography World J Urol
24.
go back to reference Margulis V, Matsumoto ED, Lindberg G, et al. (2004) Acute histologic effects of temperature-based radiofrequency ablation on renal tumor pathologic interpretation Urology 64: 660–663PubMedCrossRef Margulis V, Matsumoto ED, Lindberg G, et al. (2004) Acute histologic effects of temperature-based radiofrequency ablation on renal tumor pathologic interpretation Urology 64: 660–663PubMedCrossRef
25.
go back to reference Matsumoto ED, Johnson DB, Ogan K, et al. (2005) Short-term efficacy of temperature-based radiofrequency ablation of small renal tumors Urology 65: 877–881PubMedCrossRef Matsumoto ED, Johnson DB, Ogan K, et al. (2005) Short-term efficacy of temperature-based radiofrequency ablation of small renal tumors Urology 65: 877–881PubMedCrossRef
26.
go back to reference Varkarakis IM, Allaf ME, Inagaki T, et al. (2005) Percutaneous radio frequency ablation of renal masses: results at a 2-year mean followup J Urol 174: 456–460; discussion 460PubMedCrossRef Varkarakis IM, Allaf ME, Inagaki T, et al. (2005) Percutaneous radio frequency ablation of renal masses: results at a 2-year mean followup J Urol 174: 456–460; discussion 460PubMedCrossRef
27.
go back to reference Permpongkosol S, Link RE, Solomon SB, et al. (2006) Results of computerized tomography guided percutaneous ablation of renal masses with nondiagnostic pre-ablation pathological findings J Urol 176: 463–467; discussion 467PubMedCrossRef Permpongkosol S, Link RE, Solomon SB, et al. (2006) Results of computerized tomography guided percutaneous ablation of renal masses with nondiagnostic pre-ablation pathological findings J Urol 176: 463–467; discussion 467PubMedCrossRef
28.
go back to reference Gupta A, Raman JD, Leveillee RJ, et al. (2009) General anesthesia and contrast-enhanced computed tomography to optimize renal percutaneous radiofrequency ablation: multi-institutional intermediate-term results J Endourol 23: 1099–1105PubMedCrossRef Gupta A, Raman JD, Leveillee RJ, et al. (2009) General anesthesia and contrast-enhanced computed tomography to optimize renal percutaneous radiofrequency ablation: multi-institutional intermediate-term results J Endourol 23: 1099–1105PubMedCrossRef
29.
go back to reference Gervais DA, Arellano RS, Mueller P (2005) Percutaneous ablation of kidney tumors in nonsurgical candidates. Oncology (Williston Park) 19: 6–11 Gervais DA, Arellano RS, Mueller P (2005) Percutaneous ablation of kidney tumors in nonsurgical candidates. Oncology (Williston Park) 19: 6–11
30.
go back to reference Salagierski M, Salagierska-Barwinska A, Sosnowski M (2006) Percutaneous ultrasound-guided radiofrequency ablation for kidney tumors in patients with surgical risk Int J Urol 13: 1375–1379PubMedCrossRef Salagierski M, Salagierska-Barwinska A, Sosnowski M (2006) Percutaneous ultrasound-guided radiofrequency ablation for kidney tumors in patients with surgical risk Int J Urol 13: 1375–1379PubMedCrossRef
31.
go back to reference Hegarty NJ, Gill IS, Desai MM, et al. (2006) Probe-ablative nephron-sparing surgery: cryoablation versus radiofrequency ablation Urology 68: 7–13PubMedCrossRef Hegarty NJ, Gill IS, Desai MM, et al. (2006) Probe-ablative nephron-sparing surgery: cryoablation versus radiofrequency ablation Urology 68: 7–13PubMedCrossRef
32.
go back to reference Breen DJ, Rutherford EE, Stedman B, et al. (2007) Management of renal tumors by image-guided radiofrequency ablation: experience in 105 tumors. Cardiovasc Intervent Radiol 30: 936-942PubMedCrossRef Breen DJ, Rutherford EE, Stedman B, et al. (2007) Management of renal tumors by image-guided radiofrequency ablation: experience in 105 tumors. Cardiovasc Intervent Radiol 30: 936-942PubMedCrossRef
33.
go back to reference Veltri A, Garetto I, Pagano E, et al. (2009) Percutaneous RF thermal ablation of renal tumors: is US guidance really less favorable than other imaging guidance techniques? Cardiovasc Intervent Radiol 32: 76–85PubMedCrossRef Veltri A, Garetto I, Pagano E, et al. (2009) Percutaneous RF thermal ablation of renal tumors: is US guidance really less favorable than other imaging guidance techniques? Cardiovasc Intervent Radiol 32: 76–85PubMedCrossRef
34.
go back to reference Schirmang TC, Mayo-Smith WW, Dupuy DE, et al. (2009) Kidney neoplasms: renal halo sign after percutaneous radiofrequency ablation—incidence and clinical importance in 101 consecutive patients. Radiology 253: 263–269PubMedCrossRef Schirmang TC, Mayo-Smith WW, Dupuy DE, et al. (2009) Kidney neoplasms: renal halo sign after percutaneous radiofrequency ablation—incidence and clinical importance in 101 consecutive patients. Radiology 253: 263–269PubMedCrossRef
35.
go back to reference Farrell MA, Charboneau WJ, DiMarco DS, et al. (2003) Imaging-guided radiofrequency ablation of solid renal tumors AJR Am J Roentgenol 180: 1509–1513PubMed Farrell MA, Charboneau WJ, DiMarco DS, et al. (2003) Imaging-guided radiofrequency ablation of solid renal tumors AJR Am J Roentgenol 180: 1509–1513PubMed
36.
go back to reference Zagoria RJ, Traver MA, Werle DM, et al. (2007) Oncologic efficacy of CT-guided percutaneous radiofrequency ablation of renal cell carcinomas AJR Am J Roentgenol 189: 429–436PubMedCrossRef Zagoria RJ, Traver MA, Werle DM, et al. (2007) Oncologic efficacy of CT-guided percutaneous radiofrequency ablation of renal cell carcinomas AJR Am J Roentgenol 189: 429–436PubMedCrossRef
37.
go back to reference Frank I, Blute ML, Cheville JC, et al. (2003) Solid renal tumors: an analysis of pathological features related to tumor size J Urol 170: 2217–2220PubMedCrossRef Frank I, Blute ML, Cheville JC, et al. (2003) Solid renal tumors: an analysis of pathological features related to tumor size J Urol 170: 2217–2220PubMedCrossRef
38.
go back to reference Mahnken AH, Rohde D, Brkovic D, et al. (2005) Percutaneous radiofrequency ablation of renal cell carcinoma: preliminary results Acta Radiol 46: 208–214PubMedCrossRef Mahnken AH, Rohde D, Brkovic D, et al. (2005) Percutaneous radiofrequency ablation of renal cell carcinoma: preliminary results Acta Radiol 46: 208–214PubMedCrossRef
39.
go back to reference Goldberg SN, Grassi CJ, Cardella JF, et al. (2005) Image-guided tumor ablation: standardization of terminology and reporting criteria Radiology 235: 728–739PubMedCrossRef Goldberg SN, Grassi CJ, Cardella JF, et al. (2005) Image-guided tumor ablation: standardization of terminology and reporting criteria Radiology 235: 728–739PubMedCrossRef
40.
go back to reference Turna B, Kaouk JH, Frota R, et al. (2009) Minimally invasive nephron sparing management for renal tumors in solitary kidneys J Urol 182: 2150–2157PubMedCrossRef Turna B, Kaouk JH, Frota R, et al. (2009) Minimally invasive nephron sparing management for renal tumors in solitary kidneys J Urol 182: 2150–2157PubMedCrossRef
41.
go back to reference Lewin JS, Nour SG, Connell CF, et al. (2004) Phase II clinical trial of interactive MR imaging-guided interstitial radiofrequency thermal ablation of primary kidney tumors: initial experience Radiology 232: 835–845PubMedCrossRef Lewin JS, Nour SG, Connell CF, et al. (2004) Phase II clinical trial of interactive MR imaging-guided interstitial radiofrequency thermal ablation of primary kidney tumors: initial experience Radiology 232: 835–845PubMedCrossRef
42.
go back to reference Park S, Anderson JK, Matsumoto ED, et al. (2006) Radiofrequency ablation of renal tumors: intermediate-term results J Endourol 20: 569–573PubMedCrossRef Park S, Anderson JK, Matsumoto ED, et al. (2006) Radiofrequency ablation of renal tumors: intermediate-term results J Endourol 20: 569–573PubMedCrossRef
43.
go back to reference Levinson AW, Su LM, Agarwal D, et al. (2008) Long-term oncological and overall outcomes of percutaneous radio frequency ablation in high risk surgical patients with a solitary small renal mass J Urol 180: 499-504; discussion 504PubMedCrossRef Levinson AW, Su LM, Agarwal D, et al. (2008) Long-term oncological and overall outcomes of percutaneous radio frequency ablation in high risk surgical patients with a solitary small renal mass J Urol 180: 499-504; discussion 504PubMedCrossRef
44.
go back to reference Ahrar K, Matin S, Wood CG, et al. (2005) Percutaneous radiofrequency ablation of renal tumors: technique, complications, and outcomes J Vasc Interv Radiol 16: 679–688PubMed Ahrar K, Matin S, Wood CG, et al. (2005) Percutaneous radiofrequency ablation of renal tumors: technique, complications, and outcomes J Vasc Interv Radiol 16: 679–688PubMed
45.
go back to reference Arzola J, Baughman SM, Hernandez J, et al. (2006) Computed tomography-guided, resistance-based, percutaneous radiofrequency ablation of renal malignancies under conscious sedation at two years of follow-up Urology 68: 983–987PubMedCrossRef Arzola J, Baughman SM, Hernandez J, et al. (2006) Computed tomography-guided, resistance-based, percutaneous radiofrequency ablation of renal malignancies under conscious sedation at two years of follow-up Urology 68: 983–987PubMedCrossRef
46.
go back to reference Hoffmann RT, Jakobs TF, Kubisch CH, et al. (2010) Renal cell carcinoma in patients with a solitary kidney after nephrectomy treated with radiofrequency ablation: mid term results Eur J Radiol 73: 652–656PubMedCrossRef Hoffmann RT, Jakobs TF, Kubisch CH, et al. (2010) Renal cell carcinoma in patients with a solitary kidney after nephrectomy treated with radiofrequency ablation: mid term results Eur J Radiol 73: 652–656PubMedCrossRef
47.
go back to reference Pettus JA, Werle DM, Saunders W, et al. (2010) Percutaneous Radiofrequency Ablation Does Not Affect Glomerular Filtration Rate J Endourol Pettus JA, Werle DM, Saunders W, et al. (2010) Percutaneous Radiofrequency Ablation Does Not Affect Glomerular Filtration Rate J Endourol
48.
go back to reference Hui GC, Tuncali K, Tatli S, et al. (2008) Comparison of percutaneous and surgical approaches to renal tumor ablation: metaanalysis of effectiveness and complication rates J Vasc Interv Radiol 19: 1311–1320PubMedCrossRef Hui GC, Tuncali K, Tatli S, et al. (2008) Comparison of percutaneous and surgical approaches to renal tumor ablation: metaanalysis of effectiveness and complication rates J Vasc Interv Radiol 19: 1311–1320PubMedCrossRef
49.
go back to reference Pirasteh A, Snyder L, Boncher N, et al. (2010) Cryoablation vs. Radiofrequency Ablation for Small Renal Masses Acad Radiol Pirasteh A, Snyder L, Boncher N, et al. (2010) Cryoablation vs. Radiofrequency Ablation for Small Renal Masses Acad Radiol
Metadata
Title
Laparoscopic and Image-guided Radiofrequency Ablation of Renal Tumors: Patient Selection and Outcomes
Authors
Scott M. Castle
Vladislav Gorbatiy
Obi Ekwenna
Raymond J. Leveillee
Publication date
01-04-2011
Publisher
Current Science Inc.
Published in
Current Urology Reports / Issue 2/2011
Print ISSN: 1527-2737
Electronic ISSN: 1534-6285
DOI
https://doi.org/10.1007/s11934-010-0163-z

Other articles of this Issue 2/2011

Current Urology Reports 2/2011 Go to the issue