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Current Rheumatology Reports
Published in: Current Rheumatology Reports 12/2015

01-12-2015 | Crystal Arthritis (MH Pillinger and S Krasnokutsky, Section Editors)

Gout in the Spine: Imaging, Diagnosis, and Outcomes

Authors: Michael Toprover, Svetlana Krasnokutsky, Michael H. Pillinger

Published in: Current Rheumatology Reports | Issue 12/2015

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Abstract

Gout is characterized by the deposition of monosodium urate crystals and by acute and chronic inflammation in response to crystals so deposited. Multiple case reports and series describe the deposition of monosodium urate in the spine as a rare manifestation of gout, but the actual prevalence of spinal involvement is unknown and likely to be higher than generally anticipated. Here we review the characteristics of 131 previously reported cases of spinal involvement in gout. We focus in particular on the use of imaging modalities and the extent to which they correlate with presenting symptoms and tissue diagnoses. The recent innovation of using dual-energy computerized tomography to identify urate crystal deposition holds promise for reducing the need for surgical intervention and for establishing a true prevalence rate for spinal gout.
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Metadata
Title
Gout in the Spine: Imaging, Diagnosis, and Outcomes
Authors
Michael Toprover
Svetlana Krasnokutsky
Michael H. Pillinger
Publication date
01-12-2015
Publisher
Springer US
Published in
Current Rheumatology Reports / Issue 12/2015
Print ISSN: 1523-3774
Electronic ISSN: 1534-6307
DOI
https://doi.org/10.1007/s11926-015-0547-7
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