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01-02-2016 | Women's Mental Health (CN Epperson, Section Editor)

Bipolar Disorder in Pregnancy and Postpartum: Principles of Management

Authors: Sabrina J. Khan, Madeleine E. Fersh, Carrie Ernst, Kim Klipstein, Elizabeth Streicker Albertini, Shari I. Lusskin

Published in: Current Psychiatry Reports | Issue 2/2016

Abstract

Pregnancy and postpartum represent times of increased vulnerability for women with bipolar disorder, yet this condition remains under-diagnosed and under-treated. As 50 % of pregnancies are unplanned, the risks associated with the illness and the potential risks associated with treatment should be considered when a woman of reproductive age first presents for evaluation. This article reviews the epidemiology of perinatal bipolar disorder, screening recommendations, and treatment with pharmacotherapy and electroconvulsive therapy (ECT). An overview of the data in pregnancy and lactation is presented for lithium, lamotrigine, valproic acid, newer antipsychotics, and ECT. General principles of management include close monitoring in pregnancy and postpartum, careful adjustment of the treatment regimen to attenuate the risk of relapse, and avoidance of valproic acid when possible. Thoughtful consideration of these issues will minimize the risks to the mother and baby.

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Title: Bipolar Disorder in Pregnancy and Postpartum: Principles of Management
Authors: Sabrina J. Khan
Madeleine E. Fersh
Carrie Ernst
Kim Klipstein
Elizabeth Streicker Albertini
Shari I. Lusskin
Publication date: 01-02-2016
Publisher: Springer US
Published in: Current Psychiatry Reports / Issue 2/2016
Print ISSN: 1523-3812
Electronic ISSN: 1535-1645
DOI: https://doi.org/10.1007/s11920-015-0658-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Bipolar Disorder in Pregnancy and Postpartum: Principles of Management

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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