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Published in: Current Oncology Reports 6/2015

01-06-2015 | Lymphomas (PA Hamlin, Section Editor)

Central Nervous System Prophylaxis in Non-Hodgkin Lymphoma: Who, What, and When?

Authors: Chan Yoon Cheah, John F. Seymour

Published in: Current Oncology Reports | Issue 6/2015

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Abstract

Secondary central nervous system (CNS) progression in patients with non-Hodgkin lymphoma (NHL) is associated with a particularly poor prognosis. In this review, we summarize and critically evaluate the current literature to guide the practicing clinician in estimating CNS relapse risk in order to select individual patients who may benefit from CNS prophylaxis, covering histologic subtype, anatomic location, and molecular and clinical factors. We summarize the data regarding different prophylaxis strategies used and provide our recommendation regarding who should receive it, what they should receive, and when it should be administered.
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Metadata
Title
Central Nervous System Prophylaxis in Non-Hodgkin Lymphoma: Who, What, and When?
Authors
Chan Yoon Cheah
John F. Seymour
Publication date
01-06-2015
Publisher
Springer US
Published in
Current Oncology Reports / Issue 6/2015
Print ISSN: 1523-3790
Electronic ISSN: 1534-6269
DOI
https://doi.org/10.1007/s11912-015-0450-4

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