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Current Neurology and Neuroscience Reports

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01-04-2011 | Clinical Trial Report

Risk Stratification of Medulloblastoma: A Paradigm for Future Childhood Brain Tumor Management Strategies

Author: Roger J. Packer

Published in: Current Neurology and Neuroscience Reports | Issue 2/2011

Excerpt

Northcott PA, Korshunov A, Witt H, et al.: Medulloblastoma comprises four distinct molecular variants. J Clin Oncol 2010 Oct 4 [Epub ahead of print]. …

Packer RJ, Gajjar A, Vezina G, et al.: Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma. J Clin Oncol 22006;24(25):4202.

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Packer RJ, Gurney JG, Punyko JA, et al.: Long-term neurologic and neurosensory sequelae in adult survivors of a childhood brain tumor: childhood cancer survivor study. J Clin Oncol 2003; 21(17):3255.PubMedCrossRef

Packer RJ, Cogen P, Vezina G, et al.: Medulloblastoma: clinical and biologic aspects. Neuro Oncol 1999; 1(3):232.PubMed

Rutkowski S, Bode U, Deinlein F, et al.: Treatment of early childhood medulloblastoma by postoperative chemotherapy alone. N Engl J Med 352(10): 978, 2005.PubMedCrossRef

Gajjar A, Hernan R, Kocak M, et al.: Clinical, histopathologic, and molecular markers of prognosis: Toward a new disease risk stratification system for medulloblastoma. J Clin Oncol 22:984–993, 2004.PubMedCrossRef

Pfister S, Remke M, Benner A, et al.: Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci. J Clin Oncol 27:1627–1638, 2009.PubMedCrossRef

Kool M, Koster J, Bunt J, et al.: Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features. PLoS One 2008;3(8):e3088.PubMedCrossRef

Pomeroy SL, Tamayo P, Gaasenbeek M, et al.: Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature 415:436–442, 2002.PubMedCrossRef

Title: Risk Stratification of Medulloblastoma: A Paradigm for Future Childhood Brain Tumor Management Strategies
Author: Roger J. Packer
Publication date: 01-04-2011
Publisher: Current Science Inc.
Published in: Current Neurology and Neuroscience Reports / Issue 2/2011
Print ISSN: 1528-4042
Electronic ISSN: 1534-6293
DOI: https://doi.org/10.1007/s11910-010-0168-5

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Risk Stratification of Medulloblastoma: A Paradigm for Future Childhood Brain Tumor Management Strategies

Excerpt

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Excerpt

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