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Published in: Current Infectious Disease Reports 2/2012

01-04-2012 | Upper Respiratory, Head, and Neck Infections (I Brook, Section Editor)

Effects of Active and Passive Smoking on Ear Infections

Authors: Gonca Yilmaz, Nilgun Demirli Caylan, Can Demir Karacan

Published in: Current Infectious Disease Reports | Issue 2/2012

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Abstract

Otitis media (OM) is one of the most frequent diseases in young children, causing to visit a physician, and also the most common indication for antibiotic prescription. The peak incidence and prevalence of OM is 6 to 18 months of age. In children, second-hand smoke (SHS) exposure is associated with upper and lower respiratory tract infections, such as acute otitis media (AOM), pneumonia, and bronchitis. Despite the overwhelming evidence of the role of SHS exposure on infant health, a very high proportion of children still continue to be exposed. This important relationship between all kinds of smoking and poor health may not be appreciated universally. With this article, we aim to review tobacco smoke exposure and OM connection. How this exposure may cause OM especially in young children? What can be done to prevent and to reduce the harmfull effects of tobacco smoking?
Literature
1.
go back to reference Forgie S, Zhanel G, Robinson J. Canadian paediatric society, infectious diseases and immunization committee: antibiotic management of acute otitis media. Paediatr Child Health. 1998;3:265–7. Forgie S, Zhanel G, Robinson J. Canadian paediatric society, infectious diseases and immunization committee: antibiotic management of acute otitis media. Paediatr Child Health. 1998;3:265–7.
2.
go back to reference Marra F, Patrick DM, Chong M, Bowie WR. Antibiotic use among children in British Columbia, Canada. J Antimicrob Chemother. 2006;58:830–9.PubMedCrossRef Marra F, Patrick DM, Chong M, Bowie WR. Antibiotic use among children in British Columbia, Canada. J Antimicrob Chemother. 2006;58:830–9.PubMedCrossRef
3.
go back to reference Kerschner JE. Otitis media. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF, editors. Nelson textbook of pediatrics. Philadelphia: Saunders Elsevier; 2007. p. 2632–46. Kerschner JE. Otitis media. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF, editors. Nelson textbook of pediatrics. Philadelphia: Saunders Elsevier; 2007. p. 2632–46.
4.
go back to reference Engel J, Anteunis L, Volovics A, et al. Prevalence rates of otitis media with effusion from 0 to 2 years of age: healthy-born versus high-risk-born infants. Int J Pediatr Otorhinolaryngol. 1999;47:243–51.PubMedCrossRef Engel J, Anteunis L, Volovics A, et al. Prevalence rates of otitis media with effusion from 0 to 2 years of age: healthy-born versus high-risk-born infants. Int J Pediatr Otorhinolaryngol. 1999;47:243–51.PubMedCrossRef
5.
go back to reference Engel JA, Straetemans M, Zielhuis GA. Birth characteristics and recurrent otitis media with effusion in young children. Int J Pediatr Otorhinolaryngol. 2005;69:533–40.PubMedCrossRef Engel JA, Straetemans M, Zielhuis GA. Birth characteristics and recurrent otitis media with effusion in young children. Int J Pediatr Otorhinolaryngol. 2005;69:533–40.PubMedCrossRef
6.
go back to reference Fischer M, Hedberg K, Cardosi P, et al. Tobacco smoke as a risk factor for meningococcal disease. Pediatr Infect Dis J. 1997;16:979–83.PubMedCrossRef Fischer M, Hedberg K, Cardosi P, et al. Tobacco smoke as a risk factor for meningococcal disease. Pediatr Infect Dis J. 1997;16:979–83.PubMedCrossRef
7.
go back to reference Nuorti JP, Butler JC, Farley MM. Active bacterial core surveillance team: cigarette smoking and invasive pneumococcal disease. N Engl J Med. 2000;342:681–9.PubMedCrossRef Nuorti JP, Butler JC, Farley MM. Active bacterial core surveillance team: cigarette smoking and invasive pneumococcal disease. N Engl J Med. 2000;342:681–9.PubMedCrossRef
8.
go back to reference Bakoula CG, Kafritsa YJ, Kavadias GD, et al. Objective passive-smoking indicators and respiratory morbidity in young children. Lancet. 1995;346:280–1.PubMedCrossRef Bakoula CG, Kafritsa YJ, Kavadias GD, et al. Objective passive-smoking indicators and respiratory morbidity in young children. Lancet. 1995;346:280–1.PubMedCrossRef
9.
go back to reference DiFranza JR, Aligne CA, Weitzman M. Prenatal and postnatal environmental tobacco smoke exposure and children’s health. Pediatrics. 2004;113:1007–15.PubMed DiFranza JR, Aligne CA, Weitzman M. Prenatal and postnatal environmental tobacco smoke exposure and children’s health. Pediatrics. 2004;113:1007–15.PubMed
10.
go back to reference Ey JL, Holberg CJ, Aldous MB, et al. Passive smoking exposure and otitis media in the first year of life. Pediatrics. 1995;95:670–7.PubMed Ey JL, Holberg CJ, Aldous MB, et al. Passive smoking exposure and otitis media in the first year of life. Pediatrics. 1995;95:670–7.PubMed
11.
go back to reference Adair-Bischoff CE, Sauve RS. Environmental tobacco smoke and middle ear disease in preschool-age children. Arch Pediatr Adolesc Med. 1998;152:127–33.PubMed Adair-Bischoff CE, Sauve RS. Environmental tobacco smoke and middle ear disease in preschool-age children. Arch Pediatr Adolesc Med. 1998;152:127–33.PubMed
12.
go back to reference Lanari M, Giovannini M, Giuffre L, et al. Prevalence of respiratory syncytial virus infection in Italian infants hospitalized for acute lower respiratory tract infections, and association between respiratory syncytial virus infection risk factors and disease severity. Pediatr Pulmonol. 2002;33:458–65.PubMedCrossRef Lanari M, Giovannini M, Giuffre L, et al. Prevalence of respiratory syncytial virus infection in Italian infants hospitalized for acute lower respiratory tract infections, and association between respiratory syncytial virus infection risk factors and disease severity. Pediatr Pulmonol. 2002;33:458–65.PubMedCrossRef
13.
go back to reference Strachan DP, Cook DG. Health effects of passive smoking: 1-Parental smoking and lower respiratory illness in infancy and early childhood. Thorax. 1997;52:905–14.PubMedCrossRef Strachan DP, Cook DG. Health effects of passive smoking: 1-Parental smoking and lower respiratory illness in infancy and early childhood. Thorax. 1997;52:905–14.PubMedCrossRef
17.
go back to reference Aligne CA, Stoddard JJ. Tobacco and children: an economic evaluation of the medical effects of parental smoking. Arch Pediatr Adolesc Med. 1997;151(7):648–53.PubMedCrossRef Aligne CA, Stoddard JJ. Tobacco and children: an economic evaluation of the medical effects of parental smoking. Arch Pediatr Adolesc Med. 1997;151(7):648–53.PubMedCrossRef
18.
go back to reference The Global Youth Tobacco Survey Collaborative Group. Tobacco use among youth: a cross country comparison. Tob Control. 2002;11:252–70.CrossRef The Global Youth Tobacco Survey Collaborative Group. Tobacco use among youth: a cross country comparison. Tob Control. 2002;11:252–70.CrossRef
19.
go back to reference Tanski SE, Prokhorov AV, Klein JD. Youth and tobacco. Minerva Pediatr. 2004;56:553–65.PubMed Tanski SE, Prokhorov AV, Klein JD. Youth and tobacco. Minerva Pediatr. 2004;56:553–65.PubMed
20.
go back to reference Sargent JD, Beach ML, Adachi-Mejia AM, et al. Exposure to movie smoking: its relation to smoking initiation among US adolescents. Pediatrics. 2005;116(5):1183–91.PubMedCrossRef Sargent JD, Beach ML, Adachi-Mejia AM, et al. Exposure to movie smoking: its relation to smoking initiation among US adolescents. Pediatrics. 2005;116(5):1183–91.PubMedCrossRef
21.
go back to reference Hill KG, Hawkins JD, Catalano RF, et al. Family influences on the risk of daily smoking initiation. J Adolesc Health. 2005;37(3):202–10.PubMedCrossRef Hill KG, Hawkins JD, Catalano RF, et al. Family influences on the risk of daily smoking initiation. J Adolesc Health. 2005;37(3):202–10.PubMedCrossRef
22.
go back to reference Leatherdale ST, Brown KS, Cameron R, Mc-Donald PW. Social modeling in the school environment, student characteristics, and smoking susceptibility: a multi-level analysis. J Adolesc Health. 2005;37(4):330–6.PubMedCrossRef Leatherdale ST, Brown KS, Cameron R, Mc-Donald PW. Social modeling in the school environment, student characteristics, and smoking susceptibility: a multi-level analysis. J Adolesc Health. 2005;37(4):330–6.PubMedCrossRef
23.
go back to reference Soliman S, Pollack HA, Warner KE. Decrease in the prevalence of environmental tobacco smoke exposure in the home during the 1990s in families with children. Am J Public Health. 2004;94(2):314–20.PubMedCrossRef Soliman S, Pollack HA, Warner KE. Decrease in the prevalence of environmental tobacco smoke exposure in the home during the 1990s in families with children. Am J Public Health. 2004;94(2):314–20.PubMedCrossRef
24.
go back to reference Coghlin J, Hammond SK, Gann PH. Development of epidemiologic tools for measuring environmental tobacco smoke exposure. Am J Epidemiol. 1989;130:696–704.PubMed Coghlin J, Hammond SK, Gann PH. Development of epidemiologic tools for measuring environmental tobacco smoke exposure. Am J Epidemiol. 1989;130:696–704.PubMed
25.
go back to reference Lynch CJ. Half of selected tobacco smoke markers. Eur J Respir. 1984;65(suppl):63–7. Lynch CJ. Half of selected tobacco smoke markers. Eur J Respir. 1984;65(suppl):63–7.
26.
go back to reference Greenberg RA, Haley NJ, Etzel RA, et al. Measuring the exposure of infants to tobacco smoke: nicotine and cotinine in urine and saliva. N Eng J Med. 1984;310:1075–8.CrossRef Greenberg RA, Haley NJ, Etzel RA, et al. Measuring the exposure of infants to tobacco smoke: nicotine and cotinine in urine and saliva. N Eng J Med. 1984;310:1075–8.CrossRef
27.
go back to reference Eliopoulos C, Klein J, Phan MK, et al. Hair concentrations of nicotine and cotinine in women and their newborn infants. JAMA. 1994;271:621–3.PubMedCrossRef Eliopoulos C, Klein J, Phan MK, et al. Hair concentrations of nicotine and cotinine in women and their newborn infants. JAMA. 1994;271:621–3.PubMedCrossRef
28.
go back to reference Hengen N, Hengen M. Gas–liquid chromatographic determination of nicotine and cotinine in plasma. Clin Chem. 1978;24(1):50–3.PubMed Hengen N, Hengen M. Gas–liquid chromatographic determination of nicotine and cotinine in plasma. Clin Chem. 1978;24(1):50–3.PubMed
29.
go back to reference Feyerabend C, Russell MA. Improved gas chromatographic method and micro-extraction technique for the measurement of nicotine in biological fluids. J Pharm Pharmacol. 1979;31(2):73–6.PubMedCrossRef Feyerabend C, Russell MA. Improved gas chromatographic method and micro-extraction technique for the measurement of nicotine in biological fluids. J Pharm Pharmacol. 1979;31(2):73–6.PubMedCrossRef
30.
go back to reference Butts WC, Kuehneman M, Widdowson GM. Automated method for determining serum thiocyanate to distinguish smokers from non-smokers. Clin Chem. 1974;20:1344–8.PubMed Butts WC, Kuehneman M, Widdowson GM. Automated method for determining serum thiocyanate to distinguish smokers from non-smokers. Clin Chem. 1974;20:1344–8.PubMed
31.
go back to reference Kraemer MJ, Richardson MA, Weiss NS, et al. Risk factors for persistent middle-ear effusions. Otitis media, catarrh, cigarette smoke exposure, and atopy. JAMA. 1983;249:1022–5.PubMedCrossRef Kraemer MJ, Richardson MA, Weiss NS, et al. Risk factors for persistent middle-ear effusions. Otitis media, catarrh, cigarette smoke exposure, and atopy. JAMA. 1983;249:1022–5.PubMedCrossRef
32.
go back to reference Blakley BW, Blakley JE. Smoking and middle ear disease: are they related? A review article. Otolaryngol Head Neck Surg. 1995;112:441–6.PubMedCrossRef Blakley BW, Blakley JE. Smoking and middle ear disease: are they related? A review article. Otolaryngol Head Neck Surg. 1995;112:441–6.PubMedCrossRef
33.
go back to reference Gulya AJ. Environmental tobacco smoke and otitis media. Otolaryngol Head Neck Surg. 1994;111:6–8.PubMed Gulya AJ. Environmental tobacco smoke and otitis media. Otolaryngol Head Neck Surg. 1994;111:6–8.PubMed
34.
go back to reference Strachan DP, Cook DG. Health effects of passive smoking: 4-Parental smoking, middle ear disease and adenotonsillectomy in children. Thorax. 1998;53:50–6.PubMedCrossRef Strachan DP, Cook DG. Health effects of passive smoking: 4-Parental smoking, middle ear disease and adenotonsillectomy in children. Thorax. 1998;53:50–6.PubMedCrossRef
35.
go back to reference Ilicali OC, Keles N, Deger K, et al. Evaluation of the effect of passive smoking on otitis media in children by and objective method: urinary cotinine analysis. Laryngoscope. 2001;111:163–7.PubMedCrossRef Ilicali OC, Keles N, Deger K, et al. Evaluation of the effect of passive smoking on otitis media in children by and objective method: urinary cotinine analysis. Laryngoscope. 2001;111:163–7.PubMedCrossRef
36.
go back to reference Health Effects of Exposure to Environmental Tobacco Smoke: The report of the California environmental protection agency. Smoking and tobacco control monograph no. 10. Bethesda, MD: US Department of Health and Human Services, National Institutes of Health, National Cancer Institute; 1999. Health Effects of Exposure to Environmental Tobacco Smoke: The report of the California environmental protection agency. Smoking and tobacco control monograph no. 10. Bethesda, MD: US Department of Health and Human Services, National Institutes of Health, National Cancer Institute; 1999.
37.
go back to reference The health consequences of involuntary exposure to tobacco smoke: a report of the Surgeon General. Rockville, MD, US Department of Health and Human Services, Centers for Disease Control and Prevention; 2006. The health consequences of involuntary exposure to tobacco smoke: a report of the Surgeon General. Rockville, MD, US Department of Health and Human Services, Centers for Disease Control and Prevention; 2006.
38.
go back to reference •• Hawkins SS, Berkman L. Increased tobacco exposure in older children and its effect on asthma and ear infections. J Adolesc Health 2011; 48(6):647–50. This study emphasises that adolescants are increasingly exposed to SHS than younger children, which may increase adolescents’ vulnerability to ear infections. PubMedCrossRef •• Hawkins SS, Berkman L. Increased tobacco exposure in older children and its effect on asthma and ear infections. J Adolesc Health 2011; 48(6):647–50. This study emphasises that adolescants are increasingly exposed to SHS than younger children, which may increase adolescents’ vulnerability to ear infections. PubMedCrossRef
39.
go back to reference Colman GJ, Joyce T. Trends in smoking before, during and after pregnancy in ten states. Am J Prev Med. 2003;24:29–35.PubMedCrossRef Colman GJ, Joyce T. Trends in smoking before, during and after pregnancy in ten states. Am J Prev Med. 2003;24:29–35.PubMedCrossRef
40.
go back to reference Kum-Nji P, Meloy L, Herrod HG. Environmental tobacco smoke exposure: prevalence and mechanisms of causation of infections in children. Pediatrics. 2006;117:1745–54.PubMedCrossRef Kum-Nji P, Meloy L, Herrod HG. Environmental tobacco smoke exposure: prevalence and mechanisms of causation of infections in children. Pediatrics. 2006;117:1745–54.PubMedCrossRef
41.
go back to reference Stathis SL, O’Callaghan DM, Williams GM, et al. Maternal cigarette smoking during pregnancy is an independent predictor for symptoms of middle ear disease at five years’ postdelivery. Pediatrics. 1999;104:e16.PubMedCrossRef Stathis SL, O’Callaghan DM, Williams GM, et al. Maternal cigarette smoking during pregnancy is an independent predictor for symptoms of middle ear disease at five years’ postdelivery. Pediatrics. 1999;104:e16.PubMedCrossRef
42.
go back to reference Lieu JEC, Feinstein AR. Effect of gestational and passive smoke exposure on ear infections in children. Arch Pediatr Adolesc Med. 2002;156:147–54.PubMed Lieu JEC, Feinstein AR. Effect of gestational and passive smoke exposure on ear infections in children. Arch Pediatr Adolesc Med. 2002;156:147–54.PubMed
43.
go back to reference • Håberg SE, Bentdal YE, London SJ, et al. Pre- and postnatal parental smoking and acute otitis media in early childhood. Acta Paediatr. 2010; 99(1):99–105. This study supports earlier findings of increased occurrence of AOM in children exposed to tobacco smoke in early life in a society with low levels of exposure and high parental awareness. PubMed • Håberg SE, Bentdal YE, London SJ, et al. Pre- and postnatal parental smoking and acute otitis media in early childhood. Acta Paediatr. 2010; 99(1):99–105. This study supports earlier findings of increased occurrence of AOM in children exposed to tobacco smoke in early life in a society with low levels of exposure and high parental awareness. PubMed
44.
go back to reference •• Jones LL, Hassanien A, Cook DG. Parental smoking and the risk of middle ear disease in children: a systematic review and meta-analysis. Arch Pediatr Adolesc Med. 2011; Sep 5. These authors provide an excellent review and a sytematic meta-analysis of sixty-one epidemiological studies. •• Jones LL, Hassanien A, Cook DG. Parental smoking and the risk of middle ear disease in children: a systematic review and meta-analysis. Arch Pediatr Adolesc Med. 2011; Sep 5. These authors provide an excellent review and a sytematic meta-analysis of sixty-one epidemiological studies.
45.
go back to reference Dye JA, Adler KB. Effects of cigarette smoke on epithelial cells of the respiratory tract. Thorax. 1994;49:825–34.PubMedCrossRef Dye JA, Adler KB. Effects of cigarette smoke on epithelial cells of the respiratory tract. Thorax. 1994;49:825–34.PubMedCrossRef
46.
go back to reference Marcy TW, Merrill WW. Cigarette smoking and respiratory tract infection. Clin Chest Med. 1987;8:381–91.PubMed Marcy TW, Merrill WW. Cigarette smoking and respiratory tract infection. Clin Chest Med. 1987;8:381–91.PubMed
47.
go back to reference Richardson MA. Upper airway complications of cigarette smoking. J Allergy Clin Immunol. 1988;81:1032–5.PubMedCrossRef Richardson MA. Upper airway complications of cigarette smoking. J Allergy Clin Immunol. 1988;81:1032–5.PubMedCrossRef
48.
go back to reference Noble RC, Penny BB. Comparison of leukocyte count and function in smoking and nonsmoking young men. Infect Immun. 1975;12:550–5.PubMed Noble RC, Penny BB. Comparison of leukocyte count and function in smoking and nonsmoking young men. Infect Immun. 1975;12:550–5.PubMed
49.
go back to reference Corberand J, Nguyen F, Do AH, et al. Effect of tobacco smoking on the functions of polymorphonuclear leukocytes. Infect Immun. 1979;23:577–81.PubMed Corberand J, Nguyen F, Do AH, et al. Effect of tobacco smoking on the functions of polymorphonuclear leukocytes. Infect Immun. 1979;23:577–81.PubMed
50.
go back to reference Eichel B, Shahrik HA. Tobacco smoke toxicity: loss of human oral leukocyte function and fluidcell metabolism. Science. 1969;166:1424–8.PubMedCrossRef Eichel B, Shahrik HA. Tobacco smoke toxicity: loss of human oral leukocyte function and fluidcell metabolism. Science. 1969;166:1424–8.PubMedCrossRef
51.
go back to reference Pabst MJ, Pabst KM, Collier JA, et al. Inhibition of neutrophil and monocyte defensive functions by nicotine. J Periodontol. 1995;66:1047–55.PubMed Pabst MJ, Pabst KM, Collier JA, et al. Inhibition of neutrophil and monocyte defensive functions by nicotine. J Periodontol. 1995;66:1047–55.PubMed
52.
go back to reference Numabe Y, Ogawa T, Kamoi H, et al. Phagocytic function of salivary PMN after smoking or secondary smoking. Ann Periodontol. 1998;3:102–7.PubMedCrossRef Numabe Y, Ogawa T, Kamoi H, et al. Phagocytic function of salivary PMN after smoking or secondary smoking. Ann Periodontol. 1998;3:102–7.PubMedCrossRef
53.
go back to reference Hasseus B, Wallstrom M, Osterdahl BG, et al. Immunotoxic effects of smokeless tobacco on the accessory cell function of rat oral epithelium. Eur J Oral Sci. 1997;105:45–51.PubMedCrossRef Hasseus B, Wallstrom M, Osterdahl BG, et al. Immunotoxic effects of smokeless tobacco on the accessory cell function of rat oral epithelium. Eur J Oral Sci. 1997;105:45–51.PubMedCrossRef
54.
go back to reference Raman AS, Swinburne AJ, Fedullo AJ. Pneumococcal adherence to the buccal epithelial cells of cigarette smokers. Chest. 1983;83:23–7.PubMedCrossRef Raman AS, Swinburne AJ, Fedullo AJ. Pneumococcal adherence to the buccal epithelial cells of cigarette smokers. Chest. 1983;83:23–7.PubMedCrossRef
55.
go back to reference Fainstein V, Musher D. Bacterial adherence to pharyngeal cells in smokers, nonsmokers and chronic bronchitics. Infect Immun. 1979;26:178–82.PubMed Fainstein V, Musher D. Bacterial adherence to pharyngeal cells in smokers, nonsmokers and chronic bronchitics. Infect Immun. 1979;26:178–82.PubMed
56.
go back to reference Sopori ML, Kozak W, Savage SM, et al. Effect of nicotine on the immune system: possible regulation of immune responses by central and peripheral mechanisms. Psychoneuroendocrinology. 1998;23:189–204.PubMedCrossRef Sopori ML, Kozak W, Savage SM, et al. Effect of nicotine on the immune system: possible regulation of immune responses by central and peripheral mechanisms. Psychoneuroendocrinology. 1998;23:189–204.PubMedCrossRef
57.
go back to reference Babu KS, Arshad SH. The role of allergy in the development of airway inflammation in children. Paediatr Respir Rev. 2003;4:40–6.PubMedCrossRef Babu KS, Arshad SH. The role of allergy in the development of airway inflammation in children. Paediatr Respir Rev. 2003;4:40–6.PubMedCrossRef
58.
go back to reference Zhang S, Petro TM. The effect of nicotine on murine CD4 T cell responses. Int J Immunopharmacol. 1996;18:467–78.PubMedCrossRef Zhang S, Petro TM. The effect of nicotine on murine CD4 T cell responses. Int J Immunopharmacol. 1996;18:467–78.PubMedCrossRef
59.
60.
go back to reference Castellazzi AM, Maccario R, Moretta A, et al. Effect of active and passive smoking during pregnancy on natural killer-cell activity in infants. J Allergy Clin Immunol. 1999;103:172–3.PubMedCrossRef Castellazzi AM, Maccario R, Moretta A, et al. Effect of active and passive smoking during pregnancy on natural killer-cell activity in infants. J Allergy Clin Immunol. 1999;103:172–3.PubMedCrossRef
61.
go back to reference Murphy TF. Otitis media, bacterial colonization and the smoking parent. Clin Infect Dis. 2006;42:904–6.PubMedCrossRef Murphy TF. Otitis media, bacterial colonization and the smoking parent. Clin Infect Dis. 2006;42:904–6.PubMedCrossRef
62.
go back to reference Harabuchi Y, Faden H, Yamanaka N, et al. Nasopharyngeal colonization with nontypeable Haemophilus influenzae and recurrent otitis media. J Infect Dis. 1994;170:862–6.PubMedCrossRef Harabuchi Y, Faden H, Yamanaka N, et al. Nasopharyngeal colonization with nontypeable Haemophilus influenzae and recurrent otitis media. J Infect Dis. 1994;170:862–6.PubMedCrossRef
63.
go back to reference Bogaert D, De Groot R, Hermans PW. Streptococcus pneumoniae colonisation: the key to pneumococcal disease. Lancet Infect Dis. 2004;4:144–54.PubMedCrossRef Bogaert D, De Groot R, Hermans PW. Streptococcus pneumoniae colonisation: the key to pneumococcal disease. Lancet Infect Dis. 2004;4:144–54.PubMedCrossRef
64.
go back to reference Faden H, Duffy L, Wasielewski R, et al. Relationship between nasopharyngeal colonization and the development of otitis media in children. J Infect Dis. 1997;175:1440–5.PubMedCrossRef Faden H, Duffy L, Wasielewski R, et al. Relationship between nasopharyngeal colonization and the development of otitis media in children. J Infect Dis. 1997;175:1440–5.PubMedCrossRef
65.
go back to reference Brook I, Gober AE. Recovery of potential pathogens and interfering bacteria in the nasopharynx of smokers and nonsmokers. Chest. 2005;127:2072–5.PubMedCrossRef Brook I, Gober AE. Recovery of potential pathogens and interfering bacteria in the nasopharynx of smokers and nonsmokers. Chest. 2005;127:2072–5.PubMedCrossRef
66.
go back to reference Greenberg D, Givon-Lavi N, Broides A, et al. The contribution of smoking and exposure to tobacco smoke to Streptococcus pneumoniae and Haemophilus influenzae carriage in children and their mothers. Clin Infect Dis. 2006;42:897–903.PubMedCrossRef Greenberg D, Givon-Lavi N, Broides A, et al. The contribution of smoking and exposure to tobacco smoke to Streptococcus pneumoniae and Haemophilus influenzae carriage in children and their mothers. Clin Infect Dis. 2006;42:897–903.PubMedCrossRef
67.
go back to reference Brook I, Gober AE. Recovery of potential pathogens in the nasopharynx of healthy and otitis media-prone children and their smoking and nonsmoking parents. Ann Otol Rhinol Laryngol. 2008;117(10):727–30.PubMed Brook I, Gober AE. Recovery of potential pathogens in the nasopharynx of healthy and otitis media-prone children and their smoking and nonsmoking parents. Ann Otol Rhinol Laryngol. 2008;117(10):727–30.PubMed
68.
go back to reference Brook I, Gober AE. Effect of smoking cessation on the microbial flora. Arch Otolaryngol Head Neck Surg. 2007;133:135–8.PubMedCrossRef Brook I, Gober AE. Effect of smoking cessation on the microbial flora. Arch Otolaryngol Head Neck Surg. 2007;133:135–8.PubMedCrossRef
69.
go back to reference El Ahmer OR, Essery SD, Saadi AT, et al. The effect of cigarette smoke on adherence of respiratory pathogens to buccal epithelial cells. FEMS Immunol Med Microbiol. 1999;23:27–36.PubMedCrossRef El Ahmer OR, Essery SD, Saadi AT, et al. The effect of cigarette smoke on adherence of respiratory pathogens to buccal epithelial cells. FEMS Immunol Med Microbiol. 1999;23:27–36.PubMedCrossRef
70.
go back to reference Stanley PJ, Wilson R, Greenstone MA, et al. Effect of cigarette smoking on nasal mucociliary clearance andciliary beat frequency. Thorax. 1986;41:519–23.PubMedCrossRef Stanley PJ, Wilson R, Greenstone MA, et al. Effect of cigarette smoking on nasal mucociliary clearance andciliary beat frequency. Thorax. 1986;41:519–23.PubMedCrossRef
71.
go back to reference Merrill WW, Goodenberger D, Strober W, et al. Free secretory component and other proteins in human lung lavage. Am Rev Respir Dis. 1980;122:156–61.PubMed Merrill WW, Goodenberger D, Strober W, et al. Free secretory component and other proteins in human lung lavage. Am Rev Respir Dis. 1980;122:156–61.PubMed
72.
go back to reference Tos M, Bak-Pedersen K. Density of goblet cells in chronic secretory otitis media: findings in a biopsy material. Laryngoscope. 1975;85:377–83.PubMedCrossRef Tos M, Bak-Pedersen K. Density of goblet cells in chronic secretory otitis media: findings in a biopsy material. Laryngoscope. 1975;85:377–83.PubMedCrossRef
73.
go back to reference Giebink GS, Le CT, Paparella MM. Epidemiology of otitis media with effusion in children. Arch Otolaryngol. 1982;108:563–6.PubMedCrossRef Giebink GS, Le CT, Paparella MM. Epidemiology of otitis media with effusion in children. Arch Otolaryngol. 1982;108:563–6.PubMedCrossRef
74.
go back to reference Kawano H, Paparella MM, Ho SB, et al. Identification of MUC5B mucin gene in human middle ear with chronic otitis media. Laryngoscope. 2000;110:668–73.PubMedCrossRef Kawano H, Paparella MM, Ho SB, et al. Identification of MUC5B mucin gene in human middle ear with chronic otitis media. Laryngoscope. 2000;110:668–73.PubMedCrossRef
75.
go back to reference Moon SK, Lim DJ, Lee HK, et al. Mucin gene expression in cultured human middle ear epithelial cells. Acta Otolaryngol. 2000;120:933–9.PubMedCrossRef Moon SK, Lim DJ, Lee HK, et al. Mucin gene expression in cultured human middle ear epithelial cells. Acta Otolaryngol. 2000;120:933–9.PubMedCrossRef
76.
go back to reference • Preciado D, Lin J, Wuertz B, Rose M. Cigarette smoke activates NFκB and induces Muc5b expression in mouse middle ear cells. Laryngoscope 2008; 118(3):464–71. This study demonsrated that much as in lung cells, the activation of mucins by cigarette smoke is mediated by NF-κB in the mouse murine middle ear epithelial cells. PubMedCrossRef • Preciado D, Lin J, Wuertz B, Rose M. Cigarette smoke activates NFκB and induces Muc5b expression in mouse middle ear cells. Laryngoscope 2008; 118(3):464–71. This study demonsrated that much as in lung cells, the activation of mucins by cigarette smoke is mediated by NF-κB in the mouse murine middle ear epithelial cells. PubMedCrossRef
77.
go back to reference • Cho JG, Woo JS, Lee HM, et al. Effects of cigarette smoking on mucin production in human middle ear epithelial cells. Int J Pediatr Otorhinolaryngol. 2009; 73(10):1447–51. This study demonsrated that application of cigarette smoke solution on human middle ear cell increased the expression of MUC5AC mRNAs and proteins which play a major role in OME. PubMedCrossRef • Cho JG, Woo JS, Lee HM, et al. Effects of cigarette smoking on mucin production in human middle ear epithelial cells. Int J Pediatr Otorhinolaryngol. 2009; 73(10):1447–51. This study demonsrated that application of cigarette smoke solution on human middle ear cell increased the expression of MUC5AC mRNAs and proteins which play a major role in OME. PubMedCrossRef
78.
go back to reference • Committee on Environmental Health, Committee on Substance Abuse, Committee on Adolescence, and Committee on Native American Child Health. Tobacco use: A pediatric disease. Pediatrics 2009; 124:1474–87. These authors provide an excellent review on tobacco control strategies and the role of pediatricians in tobacco control. • Committee on Environmental Health, Committee on Substance Abuse, Committee on Adolescence, and Committee on Native American Child Health. Tobacco use: A pediatric disease. Pediatrics 2009; 124:1474–87. These authors provide an excellent review on tobacco control strategies and the role of pediatricians in tobacco control.
79.
go back to reference Fiore M, Jaen C, Baker T, et al. Treating tobacco use and dependence: 2008 update-clinical practice guideline. Rockville: US Department of Health and Human Services, Public Health Service; 2008. Fiore M, Jaen C, Baker T, et al. Treating tobacco use and dependence: 2008 update-clinical practice guideline. Rockville: US Department of Health and Human Services, Public Health Service; 2008.
80.
go back to reference McBride CM, Emmons KM, Lipkus IM. Understanding the potential of teachable moments: the case of smoking cessation. Health Educ Res. 2003;18(2):156–70.PubMedCrossRef McBride CM, Emmons KM, Lipkus IM. Understanding the potential of teachable moments: the case of smoking cessation. Health Educ Res. 2003;18(2):156–70.PubMedCrossRef
81.
go back to reference Winickoff JP, Tanski SE, McMillen RC, et al. Child health care clinicians’ use of medications to help parents quit smoking: a national parent survey. Pediatrics. 2005;115:1013–7.PubMedCrossRef Winickoff JP, Tanski SE, McMillen RC, et al. Child health care clinicians’ use of medications to help parents quit smoking: a national parent survey. Pediatrics. 2005;115:1013–7.PubMedCrossRef
82.
go back to reference Potts LA, Garwood CL. Varenicline: the newest agent for smoking cessation. Am J Health Syst Pharm. 2007;64(13):1381–4.PubMedCrossRef Potts LA, Garwood CL. Varenicline: the newest agent for smoking cessation. Am J Health Syst Pharm. 2007;64(13):1381–4.PubMedCrossRef
83.
go back to reference Ladomenou F, Moschandreas J, Kafatos A, et al. Protective effect of exclusive breastfeeding against infections during infancy: a prospective study. Arch Dis Child. 2010;95(12):1004–8.PubMedCrossRef Ladomenou F, Moschandreas J, Kafatos A, et al. Protective effect of exclusive breastfeeding against infections during infancy: a prospective study. Arch Dis Child. 2010;95(12):1004–8.PubMedCrossRef
84.
go back to reference • Yilmaz G, Hızlı Ş, Karacan C, et al. Effects of passive smoking on growth and infection rates of breast-fed and non-breastfed infants. Pediatr Int. 2009; 51:352–8. This study demonsrated that breast-feeding promoted the growth of infants who were exposed to SHS and protected them against infections. PubMedCrossRef • Yilmaz G, Hızlı Ş, Karacan C, et al. Effects of passive smoking on growth and infection rates of breast-fed and non-breastfed infants. Pediatr Int. 2009; 51:352–8. This study demonsrated that breast-feeding promoted the growth of infants who were exposed to SHS and protected them against infections. PubMedCrossRef
85.
go back to reference Quinn G, Ellison BB, Meade C, et al. Adapting smoking relapse-prevention materials for pregnant and postpartum women: formative research. Matern Child Health J. 2006;10:235–45.PubMedCrossRef Quinn G, Ellison BB, Meade C, et al. Adapting smoking relapse-prevention materials for pregnant and postpartum women: formative research. Matern Child Health J. 2006;10:235–45.PubMedCrossRef
86.
go back to reference Pulley KR, Flanders-Stepans MB. Smoking hygiene: an educational intervention to reduce respiratory symptoms in breastfeeding infants exposed to tobacco. J Perinat Educ. 2002;11(3):28–37.PubMed Pulley KR, Flanders-Stepans MB. Smoking hygiene: an educational intervention to reduce respiratory symptoms in breastfeeding infants exposed to tobacco. J Perinat Educ. 2002;11(3):28–37.PubMed
87.
go back to reference • Alpert HR, Behm I, Connolly GN, Kabir Z. Smoke-free households with children and decreasing rates of paediatric clinical encounters for otitis media in the United States. Tob Control 2011; 20(3):207–11. Authors used an ecological design to quantify trends and it was demonsrated that while percentages of homes with no-smoking rules increased and paediatric encounters for OM decreased. PubMedCrossRef • Alpert HR, Behm I, Connolly GN, Kabir Z. Smoke-free households with children and decreasing rates of paediatric clinical encounters for otitis media in the United States. Tob Control 2011; 20(3):207–11. Authors used an ecological design to quantify trends and it was demonsrated that while percentages of homes with no-smoking rules increased and paediatric encounters for OM decreased. PubMedCrossRef
Metadata
Title
Effects of Active and Passive Smoking on Ear Infections
Authors
Gonca Yilmaz
Nilgun Demirli Caylan
Can Demir Karacan
Publication date
01-04-2012
Publisher
Current Science Inc.
Published in
Current Infectious Disease Reports / Issue 2/2012
Print ISSN: 1523-3847
Electronic ISSN: 1534-3146
DOI
https://doi.org/10.1007/s11908-012-0239-7

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