Published in:
01-09-2014 | Co-infections and Comorbidity (CM Wyatt and K Sigel, Section Editors)
Vitamin D Deficiency and Altered Bone Mineral Metabolism in HIV-infected Individuals
Authors:
Allison Ross Eckard, Grace A. McComsey
Published in:
Current HIV/AIDS Reports
|
Issue 3/2014
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Abstract
Although patients with HIV infection are living decades longer than before with the advent of combination antiretroviral therapy, they have an increased rate of co-morbidities associated with chronic HIV, such as osteoporosis, cardiovascular disease, and immune dysfunction. Many of these complications are known to be affected by vitamin D status in the general population. Thus, the high rate of vitamin D deficiency among HIV-infected patients is alarming. Many observational and cohort studies have demonstrated that vitamin D deficiency is associated with these HIV-related complications, but randomized, placebo-controlled trials are limited. This paper reviews recent data on vitamin D deficiency in HIV infection.