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Current Gastroenterology Reports
Published in: Current Gastroenterology Reports 1/2011

01-02-2011

Bone Disorders in Chronic Liver Diseases

Author: Bruce A. Luxon

Published in: Current Gastroenterology Reports | Issue 1/2011

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Abstract

Bone disease is a major complication of chronic liver disease. Osteomalacia is quite uncommon despite low vitamin D levels in the majority of patients with cirrhosis. In contrast, osteoporosis is quite common, occurring in up to 50% of patients. Osteoporosis can result in spontaneous or low-impact fractures in patients with chronic liver diseases, adversely affecting morbidity, quality of life, and survival. The general biology of osteoporosis, including its pathogenesis, diagnostic tools, and rationale for treatment, have been determined largely empirically from studies of postmenopausal women with osteoporosis. Treatment regimens with modification of risk factors, use of vitamin D, and supplementation with calcium and bisphosphonates have been shown to be effective in select groups of patients with chronic liver diseases.
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Metadata
Title
Bone Disorders in Chronic Liver Diseases
Author
Bruce A. Luxon
Publication date
01-02-2011
Publisher
Current Science Inc.
Published in
Current Gastroenterology Reports / Issue 1/2011
Print ISSN: 1522-8037
Electronic ISSN: 1534-312X
DOI
https://doi.org/10.1007/s11894-010-0166-4

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