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01-04-2015 | Diabetes and Pregnancy (CJ Homko, Section Editor)

Vascular Complications in the Diabetic Pregnancy

Authors: Gustavo Leguizamón, Denise Trigubo, Juan Ignacio Pereira, María Fernanda Vera, José Alberto Fernández

Published in: Current Diabetes Reports | Issue 4/2015

Abstract

Long-standing hyperglycemia frequently leads to vasculopathy. Microvascular disease is characterized by retinopathy and nephropathy, while macrovascular involvement can affect coronary arteries. Diabetic autonomic neuropathy, when present, is generally associated with retinal and/or renal involvement. Early identification of these diabetic complications allows appropriate counseling and early treatment. Among women with diabetic vasculopathy, nephropathy, chronic hypertension, preeclampsia, preterm delivery, and fetal growth restriction are frequently observed. Furthermore, women with impaired renal function in early pregnancy have increased risk of long-term deterioration of glomerular filtration rate. Proliferative retinopathy can progress during pregnancy and 1 year after delivery, but long-term effects are not likely to occur. When coronary artery disease or gastroparesis diabeticorum are present, excessive maternal and fetal morbidity is observed. When modern management is synchronized with early medical care, favorable maternal and perinatal outcomes can be expected.

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Title: Vascular Complications in the Diabetic Pregnancy
Authors: Gustavo Leguizamón
Denise Trigubo
Juan Ignacio Pereira
María Fernanda Vera
José Alberto Fernández
Publication date: 01-04-2015
Publisher: Springer US
Published in: Current Diabetes Reports / Issue 4/2015
Print ISSN: 1534-4827
Electronic ISSN: 1539-0829
DOI: https://doi.org/10.1007/s11892-015-0586-5

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