Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Current Allergy and Asthma Reports
Published in: Current Allergy and Asthma Reports 7/2016

01-07-2016 | Food Allergy (T Green, Section Editor)

The Prevalence and Natural History of Food Allergy

Author: Jacob Kattan

Published in: Current Allergy and Asthma Reports | Issue 7/2016

Login to get access

Abstract

Numerous studies have demonstrated that the prevalence of food allergy is increasing. Not only are more children being diagnosed with food allergies, but studies suggest that when people outgrow their food allergies, it is taking longer than was previously thought. Studies in recent years have noted factors that may lead to a lower likelihood of developing a food allergy, including the early introduction of common food allergens, having a sufficient vitamin D level, or having a higher maternal intake of peanut early in pregnancy. Given a recent report that sensitization to common food allergens did not increase from the late 1980s/early 1990s to the mid-2000s, further studies will need to examine if the rise in food allergy prevalence is due to a change in the relationship between sensitization and clinical allergy or changes in the recognition and diagnosis of food allergy.
Literature
1.
Sicherer SH, Munoz-Furlong A, Godbold JH, Sampson HA. US prevalence of self-reported peanut, tree nut, and sesame allergy: 11-year follow up. J Allergy Clin Immunol. 2010;125:1322–6.CrossRefPubMed
2.
3.
Wood RA, Sicherer SH, Vickery BP, et al. The natural history of milk allergy in an observational cohort. J Allergy Clin Immunol. 2013;131:805–12.CrossRefPubMed
4.
Skripak JM, Matsui EC, Mudd K, Wood RA. The natural history of IgE-mediated cow’s milk allergy. J Allergy Clin Immunol. 2007;120:1172–7.CrossRefPubMed
5.
Savage JH, Matsui EC, Skripak JM, Wood RA. The natural history of egg allergy. J Allergy Clin Immunol. 2007;120:1413–7.CrossRefPubMed
6.
Savage JH, Limb SL, Brereton NH, Wood RA. The natural history of peanut allergy: extending our knowledge beyond childhood. J Allergy Clin Immunol. 2007;120:717–9.CrossRefPubMed
7.
Fleischer DM, Conover-Walker MK, Matsui EC, Wood RA. The natural history of tree nut allergy. J Allergy Clin Immunol. 2005;116:1087–93.CrossRefPubMed
8.
Keet CA, Matsui EC, Dhillon G, et al. The natural history of wheat allergy. Ann Allergy Asthma Immunol. 2009;102:410–5.CrossRefPubMed
9.
Rudders SA, Arias SA, Camargo Jr CA. Trends in hospitalizations for food-induced anaphylaxis in US children, 2000–2009. J Allergy Clin Immunol. 2014;134:960–2.CrossRefPubMed
10.
Bunyavanich S, Rifas-Shiman SL, Platts-Mills TA, et al. Peanut, milk, and wheat intake during pregnancy is associated with reduced allergy and asthma in children. J Allergy Clin Immunol. 2014;133:1373–82.CrossRefPubMedPubMedCentral
11.••
Du Toit G, Roberts G, Sayre PH, et al. Randomized trial of peanut consumption in infants at risk for peanut allergy. N Engl J Med. 2015;372:803–13. This study demonstrated that when tolerated, early introduction of peanut can help prevent the development of peanut allergy in high-risk infants.CrossRefPubMedPubMedCentral
12.•
Perkin MR, Logan K, Tseng A, et al. Randomized trial of introduction of allergenic foods in breast-fed infants. N Engl J Med. 2016;374:1733–43. The authors reported that early introduction of common food allergens may help prevent the development of food allergies, though regular introduction of these foods at a very young age is difficult to achieve.CrossRefPubMed
13.
Kim JS, Nowak-Wegrzyn A, Sicherer SH, et al. Dietary baked milk accelerates the resolution of cow’s milk allergy in children. J Allergy Clin Immunol. 2011;128:125–31.CrossRefPubMedPubMedCentral
14.
Leonard SA, Sampson HA, Sicherer SH, et al. Dietary baked egg accelerates resolution of egg allergy in children. J Allergy Clin Immunol. 2012;130(2):473–80.CrossRefPubMedPubMedCentral
15.
Venter C, Patil V, Grundy J, et al. Prevalence and cumulative incidence of food hypersensitivity in the first ten years of life. Pediatr Allergy Immunol. 2016.
16.
McGowan EC, Keet CA. Prevalence of self-reported food allergy in the National Health and Nutrition Examination Survey (NHANES) 2007–2010. J Allergy Clin Immunol. 2013;132:1216–9.CrossRefPubMed
17.
Gupta RS, Springston EE, Warrier MR, et al. The prevalence, severity, and distribution of childhood food allergy in the United States. Pediatrics. 2011;128:e9–17.CrossRefPubMed
18.
Branum AM, Simon AE, Lukacs SL. Food allergy among children in the United States. Pediatrics. 2009;124:1549–55.CrossRefPubMed
19.
20.
Spergel JM, Beausoleil JL, Pawlowski NA. Resolution of childhood peanut allergy. Ann Allergy Asthma Immunol. 2000;85:473–6.CrossRefPubMed
21.
Elizur A, Rajuan N, Golberg MR, et al. Natural course and risk factors for persistence of IgE-mediated cow’s milk allergy. J Pediatr. 2012;161:482–7.CrossRefPubMed
22.
Ho MH, Wong WH, Heine RG, et al. Early clinical predictors of remission of peanut allergy in children. J Allergy Clin Immunol. 2008;121:731–6.CrossRefPubMed
23.
Yavuz ST, Buyuktiryaki B, Sahiner UM, et al. Factors that predict the clinical reactivity and tolerance in children with cow’s milk allergy. Ann Allergy Asthma Immunol. 2013;110:284–9.CrossRefPubMed
24.
Czaja-Bulsa G, Bulsa M. The natural history of IgE mediated wheat allergy in children with dominant gastrointestinal symptoms. Allergy, Asthma Clin Immunol. 2014;10:12.CrossRef
25.
Boyce JA, Assa’ad A, Burks AW, et al. Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel. J Allergy Clin Immunol. 2010;126(suppl):S1–58.PubMedPubMedCentral
26.
27.
Kulig M, Bergmann R, Klettke U. Natural course of sensitization to food and inhalant allergens during the first 6 years of life. J Allergy Clin Immunol. 1999;103:1173–9.CrossRefPubMed
28.
Sampson HA, Scanlon SM. Natural history of food hypersensitivity in children with atopic dermatitis. J Pediatr. 1989;115:23–7.CrossRefPubMed
29.
Bock SA. Prospective appraisal of complaints of adverse reactions to foods in children during the first 3 years of life. Pediatrics. 1987;79:683–8.PubMed
30.
Host A, Halken S. A prospective study of cow milk allergy in Danish infants during the first 3 years of life: clinical course in relation to clinical and immunological type of hypersensitivity reaction. Allergy. 1990;45:587–96.CrossRefPubMed
31.
Nowak-Wegrzyn A, Bloom KA, Sicherer SH, et al. Tolerance to extensively heated milk in children with cow’s milk allergy. J Allergy Clin Immunol. 2008;122(2):342–7.CrossRefPubMed
32.
Rona RJ, Keil T, Summers C, et al. The prevalence of food allergy: a meta-analysis. J Allergy Clin Immunol. 2007;120:638–46.CrossRefPubMed
33.
Eggesbo M, Botten G, Halvorsen R, Magnus P. The prevalence of allergy to egg: a population-based study in young children. Allergy. 2001;56:403–11.CrossRefPubMed
34.
Gaffin JM, Sheehan WJ, Morrill J, et al. Tree nut allergy, egg allergy, and asthma in children. Clin Pediatr (Phila). 2011;50:133–9.CrossRef
35.
Soderstrom L, Lilja G, Borres MP, Nilsson C. An explorative study of low levels of allergen-specific IgE and clinical allergy symptoms during early childhood. Allergy. 2011;66:1058–64.CrossRefPubMed
36.
Liu AH, Jaramillo R, Sicherer SH, et al. National prevalence and risk factors for food allergy and relationship to asthma: results from the National Health and Nutrition Examination Survey 2005–2006. J Allergy Clin Immunol. 2010;126:798–806.CrossRefPubMedPubMedCentral
37.
Savage J, Sicherer S, Wood R. The natural history of food allergy. J Allergy Clin Immunol Pract. 2016;4:196–203.
38.
Wood RA. The natural history of food allergy. Pediatrics. 2003;111:1631–7.PubMed
39.
Lemon-Mule H, Sampson HA, Sicherer SH, et al. Immunologic changes in children with egg allergy ingesting extensively heated egg. J Allergy Clin Immunol. 2008;122:977–83.CrossRefPubMed
40.
Peters RL, Allen KJ, Dharmage SC, et al. Skin prick test responses and allergen-specific IgE levels as predictors of peanut, egg, and sesame allergy in infants. J Allergy Clin Immunol. 2013;132:874–80.CrossRefPubMed
41.
Green TD, Labelle VS, Steele PH, et al. Clinical characteristics of peanut-allergic children: recent changes. Pediatrics. 2007;120:1304–10.CrossRefPubMed
42.
Vereda A, van Hage M, Ahlstedt S, et al. Peanut allergy: clinical and immunologic differences among patients from 3 different geographic regions. J Allergy Clin Immunol. 2011;127:603–7.CrossRefPubMed
43.
Hourihane JO, Roberts SA, Warner JO. Resolution of peanut allergy: case-control study. Br Med J. 1998;316:1271–5.CrossRef
44.
Peters RL, Allen KJ, Dharmage SC, et al. Natural history of peanut allergy and predictors of resolution in the first 4 years of life: a population-based assessment. J Allergy Clin Immunol. 2015;135:1257–66.CrossRefPubMed
45.
Neuman-Sunshine DL, Eckman JA, Keet CA, et al. The natural history of persistent peanut allergy. Ann Allergy Asthma Immunol. 2012;108:326–31.CrossRefPubMed
46.
Fleischer DM, Conover-Walker MK, Christie L, et al. The natural progression of peanut allergy: resolution and the possibility of recurrence. J Allergy Clin Immunol. 2003;112:183–9.CrossRefPubMed
47.
Fleischer DM, Conover-Walker MK, Christie L, et al. Peanut allergy: recurrence and its management. J Allergy Clin Immunol. 2004;113:1195–201.CrossRef
48.
Sicherer SH, Dhillon G, Laughery KA, et al. Caution: the Phadia hazelnut ImmunoCAP (f17) has been supplemented with recombinant Cor a 1 and now detects Bet v 1-specific IgE, which leads to elevated values for persons with birch pollen allergy. J Allergy Clin Immunol. 2008;122:413–4.CrossRefPubMed
49.
Venter C, Pereira B, Gundy J, et al. Incidence of parentally reported and clinically diagnosed food hypersensitivity in the first year of life. J Allergy Clin Immunol. 2006;117:1118–24.CrossRefPubMed
50.
Poole JA, Barriga K, Leung DY, et al. Timing of initial exposure to cereal grains and the risk of wheat allergy. Pediatrics. 2006;117:2175–82.CrossRefPubMed
51.
Allen KJ, Koplin JJ, Ponsonby AL, et al. Vitamin D in sufficiency is associated with challenge-proven food allergy in infants. J Allergy Clin Immunol. 2013;131:1109–16.CrossRefPubMed
52.
Grimshaw KE, Maskell J, Oliver EM, et al. Diet and food allergy development during infancy: birth cohort study findings using prospective food diary data. J Allergy Clin Immunol. 2014;133:511–9.CrossRefPubMed
53.
Wong GW. Preventing food allergy in infancy—early consumption or avoidance? N Engl J Med. 2016;374:1783–4.CrossRefPubMed
54.
Gupta RS, Springston EE, Smith B, et al. Parent report of physician diagnosis in pediatric food allergy. J Allergy Clin Immunol. 2013;131:150–6.CrossRefPubMed
55.•
McGowan EC, Peng RD, Salo PM, et al. Changes in food-specific IgE over time in the National Health and Nutrition Examination Survey (NHANES). J Allergy Clin Immunol Pract. 2016. While food allergy prevalence has increased in recent years, this study demonstrated that sensitization to common food allergens, such as milk, egg, peanut, and shrimp, did not increase between the late 1980s/early 1990s and the mid-2000s in US children ages 6–19 years.
Metadata
Title
The Prevalence and Natural History of Food Allergy
Author
Jacob Kattan
Publication date
01-07-2016
Publisher
Springer US
Published in
Current Allergy and Asthma Reports / Issue 7/2016
Print ISSN: 1529-7322
Electronic ISSN: 1534-6315
DOI
https://doi.org/10.1007/s11882-016-0627-4

Other articles of this Issue 7/2016

Current Allergy and Asthma Reports 7/2016 Go to the issue

Basic and Applied Science (I Lewkowich, Section Editor)

Lipid Mediators of Allergic Disease: Pathways, Treatments, and Emerging Therapeutic Targets

Pediatric Allergy and Immunology (WK Dolen, Section Editor)

The Perception of Asthma Severity in Children

Allergic Skin Diseases (L Fonacier, Section Editor)

Natural (Mineral, Vegetable, Coconut, Essential) Oils and Contact Dermatitis

Anaphylaxis and Drug Allergy (DA Khan and M Castells, Section Editors)

Immediate Drug Hypersensitivity