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Published in: Current Allergy and Asthma Reports 4/2014

01-04-2014 | OCCUPATIONAL ALLERGIES (JA POOLE, SECTION EDITOR)

Occupational Irritant and Allergic Rhinitis

Author: Dennis Shusterman

Published in: Current Allergy and Asthma Reports | Issue 4/2014

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Abstract

The upper airway (extending from the nares to larynx) fulfills essential physiologic functions, including sensation, air conditioning, filtration, and communication. As the portal of entry for the respiratory tract, the upper airway’s sentinel function is performed by the olfactory and trigeminal nerves. Sensory (eye, nose and throat) irritation figures prominently in symptom reporting in so-called "problem buildings," as well as in industrial exposures to irritant gases, vapors, and smokes. Both irritants and allergens can alter function in the upper airway, leading to loss of air conditioning and filtering due to airflow obstruction and hypersecretion. Increasing evidence points to a “unified airway” model of pathogenesis (in which rhinitis may precede the development of asthma). The spectrum of occupational irritant- and allergen-related upper airway health effects—including sensory irritation, olfactory dysfunction, rhinitis, sinusitis, nasal septal perforation, and sinonasal cancer—is reviewed in this article.
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Metadata
Title
Occupational Irritant and Allergic Rhinitis
Author
Dennis Shusterman
Publication date
01-04-2014
Publisher
Springer US
Published in
Current Allergy and Asthma Reports / Issue 4/2014
Print ISSN: 1529-7322
Electronic ISSN: 1534-6315
DOI
https://doi.org/10.1007/s11882-014-0425-9

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ALLERGENS (RK BUSH AND JA WOODFOLK, SECTION EDITORS)

Recombinant Allergens for Diagnosis of Cockroach Allergy

BASIC AND APPLIED SCIENCE (M FRIERI AND PJ BRYCE, SECTION EDITORS)

Interleukin-31: A Novel Diagnostic Marker of Allergic Diseases