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Published in: Irish Journal of Medical Science (1971 -) 2/2014

01-06-2014 | Original Article

The effect of a Rapid Access Prostate Cancer Clinic on prostate cancer patient and disease characteristics, primary treatment and surgical workload

Authors: S. F. Oon, I. M. Cullen, D. Moran, E. M. Bolton, T. McDermott, R. Grainger, T. H. Lynch

Published in: Irish Journal of Medical Science (1971 -) | Issue 2/2014

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Abstract

Background

In 2009, Rapid Access Prostate Cancer Clinics (RAPC) were introduced to St. James’s Hospital to improve the access and organisation of patients to prostate cancer investigations and treatment.

Aims

To observe the effects of the RAPC on prostate cancer diagnosis, primary treatment and overall workload.

Methods

Using a prospectively designed patient database, the records of all prostate cancer patients between 2007 and 2011 were retrieved and analysed. Data were obtained for age, PSA, biopsy Gleason score and primary treatment modality and charted for the observation and comparison of trends.

Results

Seven hundred and eighty-nine patients had a new diagnosis of prostate cancer between 2007 and 2011. The median PSA prior to the RAPC was 9.7–13.1 ng/ml, which decreased to 7.79–9 ng/ml after the RAPC. Prior to the RAPC, 77–81 biopsies were performed annually versus 149–271 in the post-RAPC era. Annual requirements for radical prostatectomy also increased from 12 to 27 in the post-RAPC era. Conversely, an initially increasing percentage of patients for radiotherapy was reversed in the post-RAPC period. An increasing trend for higher grade PCa (Gleason score 4 + 4 and higher) was also reversed.

Conclusions

The introduction of a RAPC improves the overall pathological characteristics of patients with prostate cancer. However, RAPCs are also associated with a considerable increase in surgical workload. These are important considerations for units considering the incorporation of a similar facility in their institutions.
Literature
4.
go back to reference O’Kelly F, Thomas A, Murray D, Galvin D, Mulvin D, Quinlan DM (2013) Can delayed time to referral to a tertiary level urologist with an abnormal PSA level affect subsequent Gleason grade in the opportunistically screened population? Prostate. doi:10.1002/pros.22628 PubMed O’Kelly F, Thomas A, Murray D, Galvin D, Mulvin D, Quinlan DM (2013) Can delayed time to referral to a tertiary level urologist with an abnormal PSA level affect subsequent Gleason grade in the opportunistically screened population? Prostate. doi:10.​1002/​pros.​22628 PubMed
5.
go back to reference Children DoHa (2006) A strategy for cancer control in Ireland—National Cancer Forum 2006. Dublin Children DoHa (2006) A strategy for cancer control in Ireland—National Cancer Forum 2006. Dublin
6.
go back to reference Forde JC, O’Connor KM, Casey L, O’Brien M, Bowen S, Casey RG, Ahmed I, McDermott TE, Grainger R, Lynch TH (2011) A rapid access diagnostic clinic for prostate cancer: the experience after one year. Ir J Med Sci 180(2):505–508. doi:10.1007/s11845-011-0695-3 PubMedCrossRef Forde JC, O’Connor KM, Casey L, O’Brien M, Bowen S, Casey RG, Ahmed I, McDermott TE, Grainger R, Lynch TH (2011) A rapid access diagnostic clinic for prostate cancer: the experience after one year. Ir J Med Sci 180(2):505–508. doi:10.​1007/​s11845-011-0695-3 PubMedCrossRef
7.
go back to reference O’Kelly F, Thomas AZ, Murray D, Lee P, O’Carroll RF, Nicholson P, Forristal H, Swan N, Galvin D, Mulvin D, Quinlan DM (2013) Emerging evidence for Gleason grade migration and distance impact in prostate cancer? An analysis of the rapid access prostate clinic in a tertiary referral center: St. Vincent’s University Hospital, Dublin (2009-2011). Ir J Med Sci 182(3):487–491. doi:10.1007/s11845-013-0920-3 PubMedCrossRef O’Kelly F, Thomas AZ, Murray D, Lee P, O’Carroll RF, Nicholson P, Forristal H, Swan N, Galvin D, Mulvin D, Quinlan DM (2013) Emerging evidence for Gleason grade migration and distance impact in prostate cancer? An analysis of the rapid access prostate clinic in a tertiary referral center: St. Vincent’s University Hospital, Dublin (2009-2011). Ir J Med Sci 182(3):487–491. doi:10.​1007/​s11845-013-0920-3 PubMedCrossRef
8.
go back to reference Hankey BF, Feuer EJ, Clegg LX, Hayes RB, Legler JM, Prorok PC, Ries LA, Merrill RM, Kaplan RS (1999) Cancer surveillance series: interpreting trends in prostate cancer–part I: evidence of the effects of screening in recent prostate cancer incidence, mortality, and survival rates. J Natl Cancer Inst 91(12):1017–1024PubMedCrossRef Hankey BF, Feuer EJ, Clegg LX, Hayes RB, Legler JM, Prorok PC, Ries LA, Merrill RM, Kaplan RS (1999) Cancer surveillance series: interpreting trends in prostate cancer–part I: evidence of the effects of screening in recent prostate cancer incidence, mortality, and survival rates. J Natl Cancer Inst 91(12):1017–1024PubMedCrossRef
9.
go back to reference Registry NC (2010) Cancer trends—Cancer of the prostate Registry NC (2010) Cancer trends—Cancer of the prostate
10.
go back to reference Registry NC (2011) Cancer in Ireland 2011: Annual Report of the National Cancer Registry Registry NC (2011) Cancer in Ireland 2011: Annual Report of the National Cancer Registry
11.
go back to reference Epstein JI, Allsbrook WC Jr, Amin MB, Egevad LL (2005) The 2005 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason grading of prostatic carcinoma. Am J Surg Pathol 29(9):1228–1242PubMedCrossRef Epstein JI, Allsbrook WC Jr, Amin MB, Egevad LL (2005) The 2005 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason grading of prostatic carcinoma. Am J Surg Pathol 29(9):1228–1242PubMedCrossRef
Metadata
Title
The effect of a Rapid Access Prostate Cancer Clinic on prostate cancer patient and disease characteristics, primary treatment and surgical workload
Authors
S. F. Oon
I. M. Cullen
D. Moran
E. M. Bolton
T. McDermott
R. Grainger
T. H. Lynch
Publication date
01-06-2014
Publisher
Springer London
Published in
Irish Journal of Medical Science (1971 -) / Issue 2/2014
Print ISSN: 0021-1265
Electronic ISSN: 1863-4362
DOI
https://doi.org/10.1007/s11845-013-0997-8

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