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Published in: Journal of Cancer Survivorship 3/2009

01-09-2009

Dermatologic issues in adult survivors of childhood cancer

Authors: Karen E. Kinahan, Mona Gandhi, Mario E. Lacouture, Robert Eilers Jr., Anand Haryani, Aarati Didwania, Lisa K. Sharp

Published in: Journal of Cancer Survivorship | Issue 3/2009

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Abstract

Introduction

Common late effects experienced by childhood cancer survivors include: thyroid disturbances, pulmonary compromise, heart failure, and secondary neoplasms. Dermatologic issues have been largely unexplored.

Methods

This descriptive study consisted of an 8 item self-reported questionnaire on dermatologic issues and the Dermatology Life Quality Index. Participants reported dermatological issues that presented anytime after their diagnosis of cancer. Over a seven month period, 166 survivors seen in a specialized program for adult survivors of childhood cancer housed within an adult cancer center received a cover letter either through the mail or in the clinic setting which explained the purpose of the study. A total of 78 survivors completed the study with an average age of 29.7 years (range 19–46) and an average time since their diagnosis of 19.2 years (range 6–46).

Results

Dermatological issues were reported by 59.0% of survivors and 50% saw a dermatologist at least once for these concerns. Nine survivors (11.5%) reported a skin cancer and ten (12.82%) were affected by alopecia. Additionally, 26 (33.3%) of survivors reported scars related to cancer therapy as a dermatological issue, and 99% of survivors reporting scars said they did not resolve with time.

Discussion/conclusions

There are a range of dermatologic issues experienced by adult childhood cancer survivors. In our non-representative sample, 50% of the survivors sought specialized care from a dermatologist for their concern. Additional research is needed to more clearly understand the extent of dermatologic issues and their impact upon quality of life in childhood cancer survivors.

Implications for cancer survivors

Childhood cancer survivors may frequently seek care from primary care providers. It is important for these providers to be aware of the risks associated with cancer treatments.
Literature
1.
go back to reference Ries LAG, Melbert D, Krapcho M, et al., editors. SEER Cancer Statistics Review, 1975–2005, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2005/, based on November 2007 SEER data submission, posted to the SEER web site, 2008. Accessed December 15, 2008. Ries LAG, Melbert D, Krapcho M, et al., editors. SEER Cancer Statistics Review, 1975–2005, National Cancer Institute. Bethesda, MD, http://​seer.​cancer.​gov/​csr/​1975_​2005/​, based on November 2007 SEER data submission, posted to the SEER web site, 2008. Accessed December 15, 2008.
6.
go back to reference Robison LL, Mertens AC, Boice JD, et al. Study design and cohort characteristics of the childhood cancer survivor study: a multi-institutional collaborative project. Med Ped Onc. 2002;38(4):229–39.CrossRef Robison LL, Mertens AC, Boice JD, et al. Study design and cohort characteristics of the childhood cancer survivor study: a multi-institutional collaborative project. Med Ped Onc. 2002;38(4):229–39.CrossRef
10.
go back to reference Wallace H, Green D. Late effects of childhood cancer. 1st ed. New York: Oxford University Press; 2004. p. 321–3. Chapter 11, Cutaneous Complications. Wallace H, Green D. Late effects of childhood cancer. 1st ed. New York: Oxford University Press; 2004. p. 321–3. Chapter 11, Cutaneous Complications.
13.
go back to reference Johnson BA, Nunley JR. Treatment of seborrheic dermatitis. Am Fam Phys. 2000;61(9):2703–10. 2,713–4. Johnson BA, Nunley JR. Treatment of seborrheic dermatitis. Am Fam Phys. 2000;61(9):2703–10. 2,713–4.
14.
go back to reference Lindow KB, Warren C. Understanding rosacea. A guide to facilitating care. Am J Nurs. 2001;101(10):44–51.PubMed Lindow KB, Warren C. Understanding rosacea. A guide to facilitating care. Am J Nurs. 2001;101(10):44–51.PubMed
15.
22.
go back to reference Smithard A, Glazebrook C, Williams HC. The familial risk of adult acne; a comparison between first-degree relations of affected and unaffected individuals. Br J Dermatol. 2001;141:297–300. Smithard A, Glazebrook C, Williams HC. The familial risk of adult acne; a comparison between first-degree relations of affected and unaffected individuals. Br J Dermatol. 2001;141:297–300.
Metadata
Title
Dermatologic issues in adult survivors of childhood cancer
Authors
Karen E. Kinahan
Mona Gandhi
Mario E. Lacouture
Robert Eilers Jr.
Anand Haryani
Aarati Didwania
Lisa K. Sharp
Publication date
01-09-2009
Publisher
Springer US
Published in
Journal of Cancer Survivorship / Issue 3/2009
Print ISSN: 1932-2259
Electronic ISSN: 1932-2267
DOI
https://doi.org/10.1007/s11764-009-0091-4

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