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01-01-2016 | Review Article

The Impact of Bariatric Surgery on Polycystic Ovary Syndrome: a Systematic Review and Meta-analysis

Authors: Daniel Skubleny, Noah J. Switzer, Richdeep S. Gill, Mark Dykstra, Xinzhe Shi, Margaret A. Sagle, Christopher de Gara, Daniel W. Birch, Shahzeer Karmali

Published in: Obesity Surgery | Issue 1/2016

Abstract

Bariatric surgery has been proven to be a successful management strategy for morbid obesity, but limited studies exist on its effect on polycystic ovary syndrome (PCOS). A comprehensive search of electronic databases was completed. Meta-analysis was performed on PCOS, hirsutism, and menstrual irregularity outcomes following bariatric surgery. Thirteen primary studies involving a total of 2130 female patients were identified. The incidence of PCOS preoperatively was 45.6 %, which significantly decreased to 6.8 % (P < 0.001) and 7.1 % (P < 0.0002) at 12-month follow-up and study endpoint, respectively. The incidences of preoperative menstrual irregularity and hirsutism both significantly decreased at 12-month and at study end follow-up. Bariatric surgery effectively attenuates PCOS and its clinical symptomatology including hirsutism and menstrual irregularity in severely obese women.

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Title: The Impact of Bariatric Surgery on Polycystic Ovary Syndrome: a Systematic Review and Meta-analysis
Authors: Daniel Skubleny
Noah J. Switzer
Richdeep S. Gill
Mark Dykstra
Xinzhe Shi
Margaret A. Sagle
Christopher de Gara
Daniel W. Birch
Shahzeer Karmali
Publication date: 01-01-2016
Publisher: Springer US
Published in: Obesity Surgery / Issue 1/2016
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI: https://doi.org/10.1007/s11695-015-1902-5

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The Impact of Bariatric Surgery on Polycystic Ovary Syndrome: a Systematic Review and Meta-analysis

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