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Published in: Obesity Surgery 7/2015

Open Access 01-07-2015 | Review Article

The Short-Term Remission of Diabetic Nephropathy After Roux-en-Y Gastric Bypass in Chinese Patients of T2DM with Obesity

Authors: Hongwei Zhang, Jianzhong Di, Haoyong Yu, Xiaodong Han, Kun Li, Pin Zhang

Published in: Obesity Surgery | Issue 7/2015

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Abstract

The study aimed to examine the effect of gastric bypass on diabetic nephropathy (DN) in Chinese patients. A retrospective study of 101 samples with DN stages I to IV underwent Roux-en-Y gastric bypass. Anthropometric and biochemical parameters were assessed during a 1-year follow-up. Binary logistic regression analysis was used for predictors and ROC for cutoff points. There was significant reduction of medication for diabetes and hypertension. Overall remission of T2DM was 80.2 %. Preoperative albumin/creatinine ratio (ACR) and serum creatinine (SCr) levels could be predictors for DN remission, and the cutoff points were 126 mg/g cr and 57 μmol/L, respectively. Gastric bypass showed improvement of T2DM and DN. Gastric bypass may be more beneficial for those with lower preoperative ACR and SCr.
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Metadata
Title
The Short-Term Remission of Diabetic Nephropathy After Roux-en-Y Gastric Bypass in Chinese Patients of T2DM with Obesity
Authors
Hongwei Zhang
Jianzhong Di
Haoyong Yu
Xiaodong Han
Kun Li
Pin Zhang
Publication date
01-07-2015
Publisher
Springer US
Published in
Obesity Surgery / Issue 7/2015
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-015-1666-y

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