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Published in: Obesity Surgery 10/2015

01-10-2015 | Original Contributions

Laparoscopic Gastric Banding in Obese Patients with Sleep Apnea: A 3-Year Controlled Study and Follow-up After 10 Years

Authors: Barbara Feigel-Guiller, Delphine Drui, Jérôme Dimet, Yassine Zair, Maëlle Le Bras, Nuria Fuertes-Zamorano, Bertrand Cariou, Eric Letessier, Estelle Nobécourt-Dupuy, Michel Krempf

Published in: Obesity Surgery | Issue 10/2015

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Abstract

Background

The purpose of this study was to compare the effects of intensive nutritional care (INC) and laparoscopic adjustable gastric banding (LAGB) on nocturnal non-invasive ventilation (NIV) requirement in obese patients using short-, medium-, and long-term follow-up data.

Methods

This prospective randomized controlled trial included obese patients with obstructive sleep apnea (OSA) treated by NIV. Patients were randomized to the INC and LAGB groups. The primary endpoint was the theoretical rate of weaning from NIV at years 1 and 3. Data were also collected from patients 10 years after randomization.

Results

Sixty-three patients were randomized. The rate of weaning from NIV did not differ significantly between the LAGB and INC groups at year 1 (35 vs. 13 %) or year 3 (14 vs. 21 %). Percentages of excess weight loss were greater in the LAGB group than in the INC group at years 1 (33 vs. 15 %, p = 0.002) and 3 (27 vs. 8 %, p = 0.014). Decreases in the apnea-hypopnea index were observed in the LAGB group from baseline to year 1 (−44 %, p = 0.001) and from baseline to year 3 (−26 %, p = 0.044). After 10 years, the weaning rate was low and similar between groups.

Conclusion

LAGB was not superior to INC for weaning from NIV at 1 and 3 years in obese patients with OSA.
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Metadata
Title
Laparoscopic Gastric Banding in Obese Patients with Sleep Apnea: A 3-Year Controlled Study and Follow-up After 10 Years
Authors
Barbara Feigel-Guiller
Delphine Drui
Jérôme Dimet
Yassine Zair
Maëlle Le Bras
Nuria Fuertes-Zamorano
Bertrand Cariou
Eric Letessier
Estelle Nobécourt-Dupuy
Michel Krempf
Publication date
01-10-2015
Publisher
Springer US
Published in
Obesity Surgery / Issue 10/2015
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-015-1627-5

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