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Published in: Obesity Surgery 1/2009

01-01-2009 | Research Article

Successful Multi-Intervention Treatment of Severe Obesity: A 7-year Prospective Study with 96% Follow-up

Authors: Rudolf Steffen, Natascha Potoczna, Norman Bieri, Fritz F. Horber

Published in: Obesity Surgery | Issue 1/2009

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Abstract

Background

No long-term, high participation study of the outcome of bariatric surgery has examined how a multi-intervention approach to the treatment of severe obesity can achieve and sustain weight loss after an initial bariatric procedure.

Methods

We employed a multi-intervention treatment that combines adjustable gastric banding with intensive follow-up to support patient life-style change and use of an algorithm allowing reoperation—to bypass, if necessary—in the event of complications. Four hundred four severely obese patients with an average BMI = 42.6 at the outset had initial AGB surgery and were followed with a high rate of face-to-face consultations for 7 years. Seventy-five percent of the patients retained a gastric band throughout the study. Weight loss, complications, and comorbidities were studied, and quality of life was assessed using Bariatric Analysis and Reporting Outcome System (BAROS).

Results

Three hundred eighty-eight (96%) patients completed the 7-year follow-up. Average BMI reduction at 5 years was 28% and remained stable through year 7, at which the mean excess weight loss was 61%. The preoperative prevalence of metabolic syndrome, 59.7%, decreased to 13.3% at 7 years and was abolished for patients with more than 40% loss of initial BMI. Similar changes were seen for all components of metabolic syndrome. More than 60% of patients had a “good” or higher BAROS score; 10.1% were considered failures. Patients converted to gastric bypass, and those retaining gastric bands throughout the study had very similar outcomes.

Conclusions

Long-term, multi-intervention treatment of severe obesity can achieve and preserve weight loss and thus improved quality of life and sustained reduction or disappearance of all components of metabolic syndrome, for a high proportion of severely obese patients with preoperative BMI between 35 and 55.
Literature
1.
go back to reference Sjöström L, Lindroos AK, Peltonen M, et al. Swedish Obese Subjects Study Scientific Group. Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N Engl J Med. 2004;351:2683–93.CrossRef Sjöström L, Lindroos AK, Peltonen M, et al. Swedish Obese Subjects Study Scientific Group. Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N Engl J Med. 2004;351:2683–93.CrossRef
2.
go back to reference Buchwald H, Avidor Y, Braunwald E, et al. Bariatric surgery: a systematic review and meta-analysis. JAMA 2004;292:1724–37.CrossRef Buchwald H, Avidor Y, Braunwald E, et al. Bariatric surgery: a systematic review and meta-analysis. JAMA 2004;292:1724–37.CrossRef
3.
go back to reference DeMaria EJ. Bariatric surgery for morbid obesity. N Engl J Med. 2007;356:2176–83.CrossRef DeMaria EJ. Bariatric surgery for morbid obesity. N Engl J Med. 2007;356:2176–83.CrossRef
4.
go back to reference Suter M, Calmes JM, Paroz A, et al. A 10-year experience with laparoscopic gastric banding for morbid obesity: high long-term complication and failure rates. Obes Surg. 2006;16:829–35, Jul.CrossRef Suter M, Calmes JM, Paroz A, et al. A 10-year experience with laparoscopic gastric banding for morbid obesity: high long-term complication and failure rates. Obes Surg. 2006;16:829–35, Jul.CrossRef
5.
go back to reference Weber M, Müller MK, Michel JM, et al. Laparoscopic Roux-en-Y gastric bypass, but not rebanding, should be proposed as rescue procedure for patients with failed laparoscopic gastric banding. Ann Surg. 2003;238:827–34.CrossRef Weber M, Müller MK, Michel JM, et al. Laparoscopic Roux-en-Y gastric bypass, but not rebanding, should be proposed as rescue procedure for patients with failed laparoscopic gastric banding. Ann Surg. 2003;238:827–34.CrossRef
6.
go back to reference O’Brien PE, McPhail T, Chaston TB, et al. Systematic review of medium-term weight loss after bariatric operations. Obes Surg. 2006;16:1032–40, Aug.CrossRef O’Brien PE, McPhail T, Chaston TB, et al. Systematic review of medium-term weight loss after bariatric operations. Obes Surg. 2006;16:1032–40, Aug.CrossRef
7.
go back to reference Miller K, Pump A, Hell E. Vertical banded gastroplasty versus adjustable gastric banding: prospective long-term follow-up study. Surg Obes Relat Dis. 2007;3:84–90, Epub 2006 Nov 2.CrossRef Miller K, Pump A, Hell E. Vertical banded gastroplasty versus adjustable gastric banding: prospective long-term follow-up study. Surg Obes Relat Dis. 2007;3:84–90, Epub 2006 Nov 2.CrossRef
8.
go back to reference Hauri P, Steffen R, Ricklin T, et al. Treatment of morbid obesity with the Swedish Adjustable Gastric Band (SAGB): complication rate during a 12-month follow-up period. Surgery 2000;127:484–8.CrossRef Hauri P, Steffen R, Ricklin T, et al. Treatment of morbid obesity with the Swedish Adjustable Gastric Band (SAGB): complication rate during a 12-month follow-up period. Surgery 2000;127:484–8.CrossRef
9.
go back to reference Anwar M, Collins J, Kow L, et al. Long-term efficacy of a low-pressure adjustable gastric band in the treatment of morbid obesity. Ann Surg. 2008;247:771–78.CrossRef Anwar M, Collins J, Kow L, et al. Long-term efficacy of a low-pressure adjustable gastric band in the treatment of morbid obesity. Ann Surg. 2008;247:771–78.CrossRef
10.
go back to reference Biagini J, Karam L. Ten years experience with laparoscopic adjustable gastric banding. Obes Surg. 2008;18:573–7.CrossRef Biagini J, Karam L. Ten years experience with laparoscopic adjustable gastric banding. Obes Surg. 2008;18:573–7.CrossRef
11.
go back to reference Melissas J. IFSO guidelines for safety, quality, and excellence in bariatric surgery. Obes Surg. 2008;18:497–500.CrossRef Melissas J. IFSO guidelines for safety, quality, and excellence in bariatric surgery. Obes Surg. 2008;18:497–500.CrossRef
12.
go back to reference National Institutes of Health Consensus Development Conference Draft Statement. Gastrointestinal surgery for severe obesity 25–27 March. Obes Surg. 1991;1:257–65.CrossRef National Institutes of Health Consensus Development Conference Draft Statement. Gastrointestinal surgery for severe obesity 25–27 March. Obes Surg. 1991;1:257–65.CrossRef
13.
go back to reference Biertho L, Steffen R, Branson R, et al. Management of failed adjustable gastric banding. Surgery 2005;137:33–41.CrossRef Biertho L, Steffen R, Branson R, et al. Management of failed adjustable gastric banding. Surgery 2005;137:33–41.CrossRef
14.
go back to reference Oria HE, Moorehead MK. Bariatric Analysis and Reporting Outcome System (BAROS). Obes Surg. 1998;8:487–99.CrossRef Oria HE, Moorehead MK. Bariatric Analysis and Reporting Outcome System (BAROS). Obes Surg. 1998;8:487–99.CrossRef
15.
go back to reference Baldinger R, Münch R, Steffen R, et al. Conservative management of intragastric migration of Swedish adjustable gastric band by endoscopic retrieval. Gastrointest Endosc. 2001;53:98–101.CrossRef Baldinger R, Münch R, Steffen R, et al. Conservative management of intragastric migration of Swedish adjustable gastric band by endoscopic retrieval. Gastrointest Endosc. 2001;53:98–101.CrossRef
16.
go back to reference O’Brien PE, Dixon JB. Laparoscopic adjustable gastric banding in the treatment of morbid obesity. Arch Surg. 2003;138:376–82.CrossRef O’Brien PE, Dixon JB. Laparoscopic adjustable gastric banding in the treatment of morbid obesity. Arch Surg. 2003;138:376–82.CrossRef
17.
go back to reference Weiner R, Blanco-Engert R, Weiner S, et al. Outcome after laparoscopic adjustable gastric banding—8 years experience. Obes Surg. 2003;13:427–34.CrossRef Weiner R, Blanco-Engert R, Weiner S, et al. Outcome after laparoscopic adjustable gastric banding—8 years experience. Obes Surg. 2003;13:427–34.CrossRef
18.
go back to reference Mattar SG, Velcu LM, Rabinovitz M, et al. Surgically-induced weight loss significantly improves nonalcoholic fatty liver disease and the metabolic syndrome. Ann Surg. 2005;242:610–7, Discussion 618–20.PubMedPubMedCentral Mattar SG, Velcu LM, Rabinovitz M, et al. Surgically-induced weight loss significantly improves nonalcoholic fatty liver disease and the metabolic syndrome. Ann Surg. 2005;242:610–7, Discussion 618–20.PubMedPubMedCentral
19.
go back to reference Madan AK, Orth W, Ternovits CA, et al. Metabolic syndrome: yet another co-morbidity gastric bypass helps cure. Surg Obes Relat Dis. 2006;2:48–51.CrossRef Madan AK, Orth W, Ternovits CA, et al. Metabolic syndrome: yet another co-morbidity gastric bypass helps cure. Surg Obes Relat Dis. 2006;2:48–51.CrossRef
20.
go back to reference Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001;285:2486–249.CrossRef Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001;285:2486–249.CrossRef
21.
go back to reference Potoczna N, Branson R, Kral JG, et al. Gene variants and binge eating as predictors of comorbidity and outcome of treatment in severe obesity. J Gastrointest Surg. 2004;8:971–82.CrossRef Potoczna N, Branson R, Kral JG, et al. Gene variants and binge eating as predictors of comorbidity and outcome of treatment in severe obesity. J Gastrointest Surg. 2004;8:971–82.CrossRef
22.
go back to reference Moorehead MK, Ardelt-Gattinger E, Lechner H, et al. The validation of the Moorehead–Ardelt Quality of Life Questionnaire II. Obes Surg. 2003;13:684–92.CrossRef Moorehead MK, Ardelt-Gattinger E, Lechner H, et al. The validation of the Moorehead–Ardelt Quality of Life Questionnaire II. Obes Surg. 2003;13:684–92.CrossRef
23.
go back to reference Gould JC, Beverstein G, Reinhardt S, et al. Impact of routine and long-term follow-up on weight loss after laparoscopic gastric bypass. Surg Obes Relat Dis. 2007;3:627–30.CrossRef Gould JC, Beverstein G, Reinhardt S, et al. Impact of routine and long-term follow-up on weight loss after laparoscopic gastric bypass. Surg Obes Relat Dis. 2007;3:627–30.CrossRef
24.
go back to reference Shen R, Dugay G, Rajaram K, et al. Impact of patient follow-up on weight loss after bariatric surgery. Obes Surg. 2004;14:514–9.CrossRef Shen R, Dugay G, Rajaram K, et al. Impact of patient follow-up on weight loss after bariatric surgery. Obes Surg. 2004;14:514–9.CrossRef
25.
go back to reference Chiolero A, Faeh D, Paccaud F, et al. Consequences of smoking for body weight, body fat distribution, and insulin resistance. Am J Clin Nutr. 2008;87:801–9.CrossRef Chiolero A, Faeh D, Paccaud F, et al. Consequences of smoking for body weight, body fat distribution, and insulin resistance. Am J Clin Nutr. 2008;87:801–9.CrossRef
26.
go back to reference Branson R, Potoczna N, Brunotte R, et al. Impact of age, sex and body mass index on outcomes at four years after gastric banding. Obes Surg. 2005;15:834–42.CrossRef Branson R, Potoczna N, Brunotte R, et al. Impact of age, sex and body mass index on outcomes at four years after gastric banding. Obes Surg. 2005;15:834–42.CrossRef
27.
go back to reference Kral JG, Lentes KU, Horber FF. Binge eating as a phenotype of melanocortin 4 receptor gene mutations. N Engl J Med. 2003;349:608–9. Kral JG, Lentes KU, Horber FF. Binge eating as a phenotype of melanocortin 4 receptor gene mutations. N Engl J Med. 2003;349:608–9.
28.
go back to reference Martikainen T, Pirinen E, Alhava E, et al. Long-term results, late complications and quality of life in a series of adjustable gastric banding. Obes Surg. 2004;14:648–54.CrossRef Martikainen T, Pirinen E, Alhava E, et al. Long-term results, late complications and quality of life in a series of adjustable gastric banding. Obes Surg. 2004;14:648–54.CrossRef
29.
go back to reference Dargent J. Surgical treatment of morbid obesity by adjustable gastric band: the case for a conservative strategy in the case of failure—a 9-year series. Obes Surg. 2004;14:986–90.CrossRef Dargent J. Surgical treatment of morbid obesity by adjustable gastric band: the case for a conservative strategy in the case of failure—a 9-year series. Obes Surg. 2004;14:986–90.CrossRef
30.
go back to reference Naef M, Naef U, Mouton WG, et al. Outcome and complications after laparoscopic Swedish adjustable gastric banding: 5-year results of a prospective clinical trial. Obes Surg. 2007;17:195–201.CrossRef Naef M, Naef U, Mouton WG, et al. Outcome and complications after laparoscopic Swedish adjustable gastric banding: 5-year results of a prospective clinical trial. Obes Surg. 2007;17:195–201.CrossRef
31.
go back to reference Chevallier JM, Zinzindohoué F, Douard R, et al. Complications after laparoscopic adjustable gastric banding for morbid obesity: experience with 1,000 patients over 7 years. Obes Surg. 2004;14:407–14.CrossRef Chevallier JM, Zinzindohoué F, Douard R, et al. Complications after laparoscopic adjustable gastric banding for morbid obesity: experience with 1,000 patients over 7 years. Obes Surg. 2004;14:407–14.CrossRef
32.
go back to reference Favretti F, Segato G, Ashton D, et al. Laparoscopic adjustable gastric banding in 1,791 consecutive obese patients: 12-year results. Obes Surg. 2007;17:168–75.CrossRef Favretti F, Segato G, Ashton D, et al. Laparoscopic adjustable gastric banding in 1,791 consecutive obese patients: 12-year results. Obes Surg. 2007;17:168–75.CrossRef
33.
go back to reference van Wageningen B, Berends FJ, Van Ramshorst B, et al. Revision of failed laparoscopic adjustable gastric banding to Roux-en-Y gastric bypass. Obes Surg. 2006;16:137–41.CrossRef van Wageningen B, Berends FJ, Van Ramshorst B, et al. Revision of failed laparoscopic adjustable gastric banding to Roux-en-Y gastric bypass. Obes Surg. 2006;16:137–41.CrossRef
34.
go back to reference Mognol P, Chosidow D, Marmuse JP. Laparoscopic conversion of laparoscopic gastric banding to Roux-en-Y gastric bypass: a review of 70 patients. Obes Surg. 2004;14:1349–53.CrossRef Mognol P, Chosidow D, Marmuse JP. Laparoscopic conversion of laparoscopic gastric banding to Roux-en-Y gastric bypass: a review of 70 patients. Obes Surg. 2004;14:1349–53.CrossRef
35.
go back to reference Calmes JM, Giusti V, Suter M. Reoperative laparoscopic Roux-en-Y gastric bypass: an experience with 49 cases. Obes Surg. 2005;15:316–22.CrossRef Calmes JM, Giusti V, Suter M. Reoperative laparoscopic Roux-en-Y gastric bypass: an experience with 49 cases. Obes Surg. 2005;15:316–22.CrossRef
36.
go back to reference le Roux CW, Welbourn R, Werling M, et al. Gut hormones as mediators of appetite and weight loss after Roux-en-Y gastric bypass. Ann Surg. 2007;246:780–5.CrossRef le Roux CW, Welbourn R, Werling M, et al. Gut hormones as mediators of appetite and weight loss after Roux-en-Y gastric bypass. Ann Surg. 2007;246:780–5.CrossRef
37.
go back to reference Moo TA, Rubino F. Gastrointestinal surgery as treatment for type 2 diabetes. Curr Opin Endocrinol Diabetes Obes. 2008;15:153–8.CrossRef Moo TA, Rubino F. Gastrointestinal surgery as treatment for type 2 diabetes. Curr Opin Endocrinol Diabetes Obes. 2008;15:153–8.CrossRef
38.
go back to reference Pories WJ, MacDonald KG, Morgan EJ, et al. Surgical treatment of obesity and its effect on diabetes: 10-year follow-up. Am J Clin Nutr. 1992;55:582S–5.CrossRef Pories WJ, MacDonald KG, Morgan EJ, et al. Surgical treatment of obesity and its effect on diabetes: 10-year follow-up. Am J Clin Nutr. 1992;55:582S–5.CrossRef
39.
go back to reference Karlsson J, Taft C, Rydén A, et al. Ten-year trends in health-related quality of life after surgical and conventional treatment for severe obesity: the SOS intervention study. Int J Obes. 2007;31:1248–61. Aug, Epub 2007 Mar 13CrossRef Karlsson J, Taft C, Rydén A, et al. Ten-year trends in health-related quality of life after surgical and conventional treatment for severe obesity: the SOS intervention study. Int J Obes. 2007;31:1248–61. Aug, Epub 2007 Mar 13CrossRef
41.
go back to reference Adams TD, Gress RE, Smith SC, et al. Long-term mortality after gastric bypass surgery. N Engl J Med. 2007;357:753–61.CrossRef Adams TD, Gress RE, Smith SC, et al. Long-term mortality after gastric bypass surgery. N Engl J Med. 2007;357:753–61.CrossRef
42.
go back to reference Sjöström L, Narbro K, Sjöström CD, et al. Swedish Obese Subjects Study. Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med. 2007;357:741–52.CrossRef Sjöström L, Narbro K, Sjöström CD, et al. Swedish Obese Subjects Study. Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med. 2007;357:741–52.CrossRef
43.
go back to reference Korenkov M, Sauerland S. Clinical update: bariatric surgery. Lancet 2007;370:1988–90.CrossRef Korenkov M, Sauerland S. Clinical update: bariatric surgery. Lancet 2007;370:1988–90.CrossRef
Metadata
Title
Successful Multi-Intervention Treatment of Severe Obesity: A 7-year Prospective Study with 96% Follow-up
Authors
Rudolf Steffen
Natascha Potoczna
Norman Bieri
Fritz F. Horber
Publication date
01-01-2009
Publisher
Springer New York
Published in
Obesity Surgery / Issue 1/2009
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-008-9675-8

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