Skip to main content
Top
Published in: Obesity Surgery 5/2008

01-05-2008 | Research Article

Pregnancy Following Gastric Bypass Surgery for Morbid Obesity: Maternal and Neonatal Outcomes

Authors: Joseph R. Wax, Angelina Cartin, Renee Wolff, Sharon Lepich, Michael G. Pinette, Jacquelyn Blackstone

Published in: Obesity Surgery | Issue 5/2008

Login to get access

Abstract

Background

The purpose of this study was to compare obstetric and neonatal outcomes after Roux-en-Y gastric bypass (RYGB) to those in women without such surgery.

Methods

Women with RYGB (cases) were matched for maternal age and prior cesarean to the next two consecutive women delivering without prior bariatric surgery (controls). Pregnancy and newborn outcomes were compared by univariate analysis. Outcomes approaching or reaching statistical significance were evaluated by conditional logistic regression controlling for maternal body mass index (BMI).

Results

Despite gastric bypass, the 38 cases were heavier (BMI 33.4 ± 7.3 vs. 28.1 ± 6.7 kg/m2, p < 0.001) and more often obese (BMI ≥ 30 kg/m2, 26/38 (68.4%) vs. 20/76 (26.3%), p < 0.001) than controls. Variables evaluated by logistic regression adjusted for BMI did not differ in cases versus controls, including hypertension (odds ratio [OR] 2.62, 95% confidence interval [CI] 0.66–10.50), preterm premature rupture of membranes (OR 0.24, 95% CI 0.02–3.38), oligohydramnios (OR 2.39, 95% CI 0.66–8.61), and delivery ≥41 weeks (OR 0.57, 95% CI 0.11–2.97).

Discussion

Obstetric and neonatal outcomes after RYGB are similar to those of our general obstetric population.
Literature
1.
go back to reference Ogden CL, Carroll MD, Curtin LR, et al. Prevalence of overweight and obesity in the United States, 1999–2004. JAMA. 2006;295:1549–55.PubMedCrossRef Ogden CL, Carroll MD, Curtin LR, et al. Prevalence of overweight and obesity in the United States, 1999–2004. JAMA. 2006;295:1549–55.PubMedCrossRef
2.
go back to reference Gastrointestinal surgery for severe obesity. NIH consensus statement. Online 1991, Mar 25–27 [2006 December 23];9(1):1–20. Gastrointestinal surgery for severe obesity. NIH consensus statement. Online 1991, Mar 25–27 [2006 December 23];9(1):1–20.
3.
go back to reference Obesity in pregnancy. ACOG Committee Opinion 315. American College of Obstetricians and Gynecologists. Obstet Gynecol. 2005;106:671–5. Obesity in pregnancy. ACOG Committee Opinion 315. American College of Obstetricians and Gynecologists. Obstet Gynecol. 2005;106:671–5.
4.
go back to reference Buchwald H. Consensus conference statement. Bariatric surgery for morbid obesity: health implications for patients, health professionals, and third party payers. J Am Coll Surg. 2005;200:593–604.PubMedCrossRef Buchwald H. Consensus conference statement. Bariatric surgery for morbid obesity: health implications for patients, health professionals, and third party payers. J Am Coll Surg. 2005;200:593–604.PubMedCrossRef
5.
go back to reference National Center for Health Statistics. Health, United States, 2006 with chartbook on trends in the health of Americans. Hyattsville, MD; 2006. National Center for Health Statistics. Health, United States, 2006 with chartbook on trends in the health of Americans. Hyattsville, MD; 2006.
6.
go back to reference Richards DS, Miller DK, Goodman GN. Pregnancy after gastric bypass for morbid obesity. J Reprod Med. 1987;32:172–6.PubMed Richards DS, Miller DK, Goodman GN. Pregnancy after gastric bypass for morbid obesity. J Reprod Med. 1987;32:172–6.PubMed
7.
go back to reference Wittgrove AC, Jester L, Wittgrove P, et al. Pregnancy following gastric bypass for morbid obesity. Obes Surg. 1998;8:461–4.PubMedCrossRef Wittgrove AC, Jester L, Wittgrove P, et al. Pregnancy following gastric bypass for morbid obesity. Obes Surg. 1998;8:461–4.PubMedCrossRef
8.
go back to reference Printen KJ, Scott D. Pregnancy following gastric bypass for the treatment of morbid obesity. Am Surg. 1982;48:363–5.PubMed Printen KJ, Scott D. Pregnancy following gastric bypass for the treatment of morbid obesity. Am Surg. 1982;48:363–5.PubMed
9.
go back to reference Rand CW, Macgregor AM. Medical care and pregnancy outcome after gastric bypass surgery for obesity. South Med J. 1989;82:1319–20.PubMed Rand CW, Macgregor AM. Medical care and pregnancy outcome after gastric bypass surgery for obesity. South Med J. 1989;82:1319–20.PubMed
10.
go back to reference Dao T, Kuhn J, Ehmer D, et al. Pregnancy outcomes after gastric-bypass surgery. Am J Surg. 2006;192:762–6.PubMedCrossRef Dao T, Kuhn J, Ehmer D, et al. Pregnancy outcomes after gastric-bypass surgery. Am J Surg. 2006;192:762–6.PubMedCrossRef
11.
go back to reference Wax JR, Wolff R, Cobean R, et al. Intussusception complicating pregnancy following Roux-en-Y gastric bypass. Obes Surg. 2007;17:977–9.PubMedCrossRef Wax JR, Wolff R, Cobean R, et al. Intussusception complicating pregnancy following Roux-en-Y gastric bypass. Obes Surg. 2007;17:977–9.PubMedCrossRef
12.
go back to reference Wax JR, Heersink D, Pinette MG, et al. Symptomatic hypoglycemia complicating pregnancy following gastric bypass. Obes Surg. 2007;17:698–700.PubMedCrossRef Wax JR, Heersink D, Pinette MG, et al. Symptomatic hypoglycemia complicating pregnancy following gastric bypass. Obes Surg. 2007;17:698–700.PubMedCrossRef
13.
go back to reference Hadlock FP, Harrist RB, Marinez-Poyer J. In utero analysis of fetal growth: a sonographic weight standard. Radiology. 1991;181:129–33.PubMed Hadlock FP, Harrist RB, Marinez-Poyer J. In utero analysis of fetal growth: a sonographic weight standard. Radiology. 1991;181:129–33.PubMed
14.
go back to reference Wax JR, Pinette MG, Cartin A, et al. Female reproductive issues following bariatric surgery. Obstet Gynecol Surv. 2007;62:595–604.PubMedCrossRef Wax JR, Pinette MG, Cartin A, et al. Female reproductive issues following bariatric surgery. Obstet Gynecol Surv. 2007;62:595–604.PubMedCrossRef
15.
go back to reference Haddow JE, Hill LE, Kloza EM, et al. Neural tube defects after gastric bypass. Lancet. 1986;1:1330.PubMedCrossRef Haddow JE, Hill LE, Kloza EM, et al. Neural tube defects after gastric bypass. Lancet. 1986;1:1330.PubMedCrossRef
16.
17.
go back to reference Hanley JA, Lippman-Hand A. If nothing goes wrong, is everything all right? Interpreting zero numerators. JAMA. 1983;249:1743–5.PubMedCrossRef Hanley JA, Lippman-Hand A. If nothing goes wrong, is everything all right? Interpreting zero numerators. JAMA. 1983;249:1743–5.PubMedCrossRef
18.
go back to reference Kral JG, Brolin RE, Buchwald H, et al. Research considerations in obesity surgery. Obes Res. 2002;10:63–4.PubMedCrossRef Kral JG, Brolin RE, Buchwald H, et al. Research considerations in obesity surgery. Obes Res. 2002;10:63–4.PubMedCrossRef
Metadata
Title
Pregnancy Following Gastric Bypass Surgery for Morbid Obesity: Maternal and Neonatal Outcomes
Authors
Joseph R. Wax
Angelina Cartin
Renee Wolff
Sharon Lepich
Michael G. Pinette
Jacquelyn Blackstone
Publication date
01-05-2008
Publisher
Springer-Verlag
Published in
Obesity Surgery / Issue 5/2008
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-008-9459-1

Other articles of this Issue 5/2008

Obesity Surgery 5/2008 Go to the issue