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Archives of Osteoporosis

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01-12-2022 | Osteoporosis | Original Article

The pattern and trends of disease burden due to low bone mineral density from 1990 to 2019 in China: findings from the Global Burden of Disease Study 2019

Authors: Zena Chen, Ya Wen, Minli Qiu, Linkai Fang, Ou Jin, Jieruo Gu

Published in: Archives of Osteoporosis | Issue 1/2022

Abstract

Summary

Osteoporosis is becoming increasing important health problem in China. This study shows that the disease burden of low bone mineral density (BMD) in China is large and will remain increasing with the growth of aging population. In addition, male low BMD should not be ignored. Although burden of low BMD is partially representative of the real burden of osteoporosis, the information provided in our study could be used to better inform targeted public health prevention and management programs for osteopososis.

Purpose

We aim to investigate the pattern and trends of disease burden due to low BMD by gender, year, and age in China from 1990 to 2019.

Methods

Data on summary exposure value (SEV) and disability-adjusted life years (DALYs) due to low BMD was obtained from the Global Burden of Disease Study 2019, and analyzed by gender, age, and years. Average annual percent change (AAPC) and annual percent change (APC) were calculated to qualify the trends of burden due to low BMD.

Result

In 2019, the age-standardized SEV was higher in females than that in males (23.04, 95% UI = [17.25–29.83] and 12.50, 95% UI = [7.71–19.25], respectively), while the total number of DALYs was higher in males than females with 1,698,705.92 (95% UI = 1,281,580.79 to 2,076,364.25) and 1,621,569 (95% UI = 1,266,284.89 to 2,016,399.16), respectively. Though SEV exhibited decreasing trends during 1990 to 2019 in both sexes, the absolute number of DALYs due to low BMD increased steadily and almost doubled in 2019 compared to that in 1990.

Conclusion

The burden of low BMD remains large and continues to increase. Although females are prone to low BMD, the disease burden for males should not be ignored.

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Title: The pattern and trends of disease burden due to low bone mineral density from 1990 to 2019 in China: findings from the Global Burden of Disease Study 2019
Authors: Zena Chen
Ya Wen
Minli Qiu
Linkai Fang
Ou Jin
Jieruo Gu
Publication date: 01-12-2022
Publisher: Springer London
Keywords: Osteoporosis
Osteoporosis
Published in: Archives of Osteoporosis / Issue 1/2022
Print ISSN: 1862-3522
Electronic ISSN: 1862-3514
DOI: https://doi.org/10.1007/s11657-022-01079-9

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The pattern and trends of disease burden due to low bone mineral density from 1990 to 2019 in China: findings from the Global Burden of Disease Study 2019

Abstract

Summary

Purpose

Methods

Result

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Summary

Purpose

Methods

Result

Conclusion

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