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Journal of Gastrointestinal Surgery

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01-03-2020 | Esophagography | Original Article

Clinical Outcomes of Minimally Invasive Enucleation of Leiomyoma of the Esophagus and Esophagogastric Junction

Authors: Pamela Milito, Emanuele Asti, Alberto Aiolfi, Simone Zanghi, Stefano Siboni, Luigi Bonavina

Published in: Journal of Gastrointestinal Surgery | Issue 3/2020

Abstract

Objective

Minimally invasive enucleation is the treatment of choice in symptomatic patients with esophageal leiomyoma. Comprehensive long-term follow-up data are lacking. Aim of this study was to review the clinical outcomes of three procedures for enucleation of leiomyoma of the esophagus and esophagogastric junction.

Methods

A single institution retrospective review was performed using a prospectively collected research database and individual medical records. Demographics, presenting symptoms, use of proton-pump inhibitors (PPI), tumor location and size, treatment modalities, and subjective and objective clinical outcomes were recorded. Barium swallow and upper gastrointestinal endoscopy were routinely performed during the follow-up. Gastroesophageal Reflux Disease-Health Related Quality of Life (GERD-HRQL) and Short-Form 36 questionnaires were used to compare quality of life before and after treatment.

Results

Between 2002 and 2017, 35 patients underwent minimally invasive leiomyoma enucleation through thoracoscopy (n = 15), laparoscopy (n = 15), and endoscopy (n = 5). The overall morbidity rate was 14.3% and there was no mortality. All patients had a minimum of 1-year follow-up. The median follow-up was 49 (IQR 54) months, and there were no recurrences of leiomyoma. At the latest follow-up, the SF-36 scores were unchanged compared to baseline. However, there was a higher incidence of reflux symptoms (p < 0.050) and PPI use (p < 0.050) after endoscopic treatment.

Conclusions

Minimally invasive enucleation is safe and effective and can be performed by a variety of approaches according to leiomyoma location and morphology. Overall, health-related quality of life outcomes of each procedure appear satisfactory, but PPI dependence was greater in the endoscopic group.

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Title: Clinical Outcomes of Minimally Invasive Enucleation of Leiomyoma of the Esophagus and Esophagogastric Junction
Authors: Pamela Milito
Emanuele Asti
Alberto Aiolfi
Simone Zanghi
Stefano Siboni
Luigi Bonavina
Publication date: 01-03-2020
Publisher: Springer US
Keywords: Esophagography
Endoscopy
Laparoscopy
Thoracoscopy
Gastroesophageal Reflux Disease
Gastric Fundoplication
Gastric Fundoplication
Upper and Lower Gastrointestinal Endoscopy
Published in: Journal of Gastrointestinal Surgery / Issue 3/2020
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI: https://doi.org/10.1007/s11605-019-04210-3

2024 ASCO Annual Meeting

Springer Medicine

Clinical Outcomes of Minimally Invasive Enucleation of Leiomyoma of the Esophagus and Esophagogastric Junction

Abstract

Objective

Methods

Results

Conclusions

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Objective

Methods

Results

Conclusions

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