Skip to main content
Top
Published in: Journal of Gastrointestinal Surgery 7/2010

01-07-2010 | Original Article

Does Primary Surgical Management of Liver Hydatid Cyst Influence Recurrence?

Authors: Hadj Omar El Malki, Yasser El Mejdoubi, Amine Souadka, Belkacem Zakri, Raouf Mohsine, Lahcen Ifrine, Redouane Abouqal, Abdelkader Belkouchi

Published in: Journal of Gastrointestinal Surgery | Issue 7/2010

Login to get access

Abstract

Background and aims

Hydatid disease is still a major health problem in sheep-raising areas. Surgery remains the basic treatment for liver hydatid cyst (LHC). However, recurrences can occur after all therapies. Surgery for recurrence of LHC becomes technically more difficult with higher rate of morbidity and mortality. The aim of this study was to determine perfective factors associated to hepatic recurrence after LHC surgery and to propose and discuss postoperative follow-up schedules.

Methods

It is a retrospective cohort study of 672 patients with LHC treated at the surgery department “A” at Ibn Sina University Hospital, Rabat, Morocco, from January 1990 to December 2004. Recurrence rates have been analyzed by the Kaplan–Meier method for patients undergoing surgery.

Results

Fifty-six patients (8.5%) had LHC recurrence after surgery. There were 34 females (60.7%) and 22 males (39.3%). Median duration of recurrence's diagnosis was 24 months (interquartile range: 10–48 months). Recurrence's risk was 2.3% ± 0.6% at 1 year and 9.1% ± 1.3% at the 10th year. The history of LHC (hazard ratio, 2; 95% confidential interval, 1.13–3.59) and three cysts or more (hazard ratio, 3.8; 95% confidential interval, 2.07–6.98) was an independent risk factor for recurrence.

Conclusion

We think that the surgeon's practice and experience are the most important to success the surgical treatment. It prevents complications and recurrences.
Literature
1.
go back to reference Service des maladies parasitaires et service de lutte antivectorielle. Rapport annuel d'activités: Etat d'avancement des programmes de lutte contre les maladies parasitaires. Royaume du Maroc Ministère de la santé Direction de l'épidémiologie et de lutte contre les maladies. 2004 Service des maladies parasitaires et service de lutte antivectorielle. Rapport annuel d'activités: Etat d'avancement des programmes de lutte contre les maladies parasitaires. Royaume du Maroc Ministère de la santé Direction de l'épidémiologie et de lutte contre les maladies. 2004
2.
go back to reference El Malki HO, El Mejdoubi Y, Souadka Am, Mohsine R, Ifrine L, Abouqal R, Belkouchi A. Predictive factors of deep abdominal complications after operation for hydatid cyst of the liver: 15 years of experience with 672 patients. J Am Coll Surg 2008;206:629–637. El Malki HO, El Mejdoubi Y, Souadka Am, Mohsine R, Ifrine L, Abouqal R, Belkouchi A. Predictive factors of deep abdominal complications after operation for hydatid cyst of the liver: 15 years of experience with 672 patients. J Am Coll Surg 2008;206:629–637.
3.
go back to reference Smego RA Jr, Bhatti S, Khaliq AA, Beg MA. Percutaneous aspiration-injection-reaspiration drainage plus albendazole or mebendazole for hepatic cystic echinococcosis: a meta-analysis. Clin Infect Dis 2003;37:1073–1083.CrossRefPubMed Smego RA Jr, Bhatti S, Khaliq AA, Beg MA. Percutaneous aspiration-injection-reaspiration drainage plus albendazole or mebendazole for hepatic cystic echinococcosis: a meta-analysis. Clin Infect Dis 2003;37:1073–1083.CrossRefPubMed
4.
go back to reference Ustunsoz B, Akhan O, Kamiloglu MA, Somuncu I, Ugurel MS, Cetiner S. Percutaneous treatment of hydatid cysts of the liver: long-term results. AJR Am J Roentgenol 1999;172:91–96.PubMed Ustunsoz B, Akhan O, Kamiloglu MA, Somuncu I, Ugurel MS, Cetiner S. Percutaneous treatment of hydatid cysts of the liver: long-term results. AJR Am J Roentgenol 1999;172:91–96.PubMed
5.
go back to reference Klutman NE, Delcore R, Hinthorn DR. Combined albendazole and surgical therapy for echinococcal liver cysts. Infect Dis Clin Pract 1997;6:159–165. Klutman NE, Delcore R, Hinthorn DR. Combined albendazole and surgical therapy for echinococcal liver cysts. Infect Dis Clin Pract 1997;6:159–165.
6.
go back to reference Safioleas MC, Misiakos EP, Kouvaraki M, Stamatakos MK, Manti CP, Felekouras ES. Hydatid disease of the liver: a continuing surgical problem. Arch Surg 2006;141:1101–1108.CrossRefPubMed Safioleas MC, Misiakos EP, Kouvaraki M, Stamatakos MK, Manti CP, Felekouras ES. Hydatid disease of the liver: a continuing surgical problem. Arch Surg 2006;141:1101–1108.CrossRefPubMed
7.
go back to reference Karavias DD, Vagianos CE, Bouboulis N, Rathosis S, Androulakis J. Improved techniques in the surgical treatment of hepatic hydatidosis. Surg Gynecol Obstet 1992;174:176–180.PubMed Karavias DD, Vagianos CE, Bouboulis N, Rathosis S, Androulakis J. Improved techniques in the surgical treatment of hepatic hydatidosis. Surg Gynecol Obstet 1992;174:176–180.PubMed
8.
go back to reference Vagianos CE, Karavias DD, Kakkos SK, Vagenas CA, Androulakis JA. Conservative surgery in the treatment of hepatic hydatidosis. Eur J Surg 1995;161:415–420.PubMed Vagianos CE, Karavias DD, Kakkos SK, Vagenas CA, Androulakis JA. Conservative surgery in the treatment of hepatic hydatidosis. Eur J Surg 1995;161:415–420.PubMed
9.
go back to reference Akgun Y, Yilmaz G. Efficiency of obliteration procedures in the surgical treatment of hydatid cyst of the liver. ANZ J Surg 2004;74:968–973.CrossRefPubMed Akgun Y, Yilmaz G. Efficiency of obliteration procedures in the surgical treatment of hydatid cyst of the liver. ANZ J Surg 2004;74:968–973.CrossRefPubMed
10.
go back to reference Chautems R, Bühler LH, Gold B, Giostra E, Poletti P, Chilcott M, Morel P, Mentha G. Surgical management and long-term outcome of complicated liver hydatid cysts caused by Echinococcus granulosus. Surgery 2005;137:312–316.CrossRefPubMed Chautems R, Bühler LH, Gold B, Giostra E, Poletti P, Chilcott M, Morel P, Mentha G. Surgical management and long-term outcome of complicated liver hydatid cysts caused by Echinococcus granulosus. Surgery 2005;137:312–316.CrossRefPubMed
11.
go back to reference Kapan M, Kapan S, Goksoy E, Perek S, Kol E. Postoperative recurrence in hepatic hydatid disease. J Gastrointest Surg 2006;10:734–739.CrossRefPubMed Kapan M, Kapan S, Goksoy E, Perek S, Kol E. Postoperative recurrence in hepatic hydatid disease. J Gastrointest Surg 2006;10:734–739.CrossRefPubMed
12.
go back to reference Atmatzidis KS, Pavlidis TE, Papaziogas BT, Mirelis C, Papaziogas TB. Recurrence and long-term outcome after open cystectomy with omentoplasty for hepatic hydatid disease in an endemic area. Acta Chir Belg 2005;105:198–202.PubMed Atmatzidis KS, Pavlidis TE, Papaziogas BT, Mirelis C, Papaziogas TB. Recurrence and long-term outcome after open cystectomy with omentoplasty for hepatic hydatid disease in an endemic area. Acta Chir Belg 2005;105:198–202.PubMed
13.
go back to reference Gollackner B, Längle F, Auer H, Maier A, Mittlböck M, Agstner I, Karner J, Langer F, Aspöck H, Loidolt H, Rockenschaub S, Steininger R. Radical surgical therapy of abdominal cystic hydatid disease: factors of recurrence. World J Surg 2000;24:717–721.CrossRefPubMed Gollackner B, Längle F, Auer H, Maier A, Mittlböck M, Agstner I, Karner J, Langer F, Aspöck H, Loidolt H, Rockenschaub S, Steininger R. Radical surgical therapy of abdominal cystic hydatid disease: factors of recurrence. World J Surg 2000;24:717–721.CrossRefPubMed
14.
go back to reference Cirenei A, Bertoldi I. Evolution of surgery for liver hydatidosis from 1950 to today: analysis of a personal experience. World J Surg 2001;25:87–92.CrossRefPubMed Cirenei A, Bertoldi I. Evolution of surgery for liver hydatidosis from 1950 to today: analysis of a personal experience. World J Surg 2001;25:87–92.CrossRefPubMed
15.
16.
17.
go back to reference Yorganci K, Sayek I. Surgical treatment of hydatid cysts of the liver in the era of percutaneous treatment. Am J Surg 2002;184:63–69.CrossRefPubMed Yorganci K, Sayek I. Surgical treatment of hydatid cysts of the liver in the era of percutaneous treatment. Am J Surg 2002;184:63–69.CrossRefPubMed
18.
go back to reference Turkçapar AG, Ersoz S, Gungor C, Aydinuraz K, Yerdel MA, Aras N. Surgical treatment of hepatic hydatidosis combined with perioperative treatment with albendazole. Eur J Surg 1997;163:923–928.PubMed Turkçapar AG, Ersoz S, Gungor C, Aydinuraz K, Yerdel MA, Aras N. Surgical treatment of hepatic hydatidosis combined with perioperative treatment with albendazole. Eur J Surg 1997;163:923–928.PubMed
19.
go back to reference Agaoglu N, Turkyilmaz S, Arslan MK. Surgical treatment of hydatid cysts of the liver. Br J Surg 2003;90:1536–1541.CrossRefPubMed Agaoglu N, Turkyilmaz S, Arslan MK. Surgical treatment of hydatid cysts of the liver. Br J Surg 2003;90:1536–1541.CrossRefPubMed
20.
go back to reference Dervenis C, Delis S, Avgerinos C, Madariaga J, Milicevic M. Changing concepts in the management of liver hydatid disease. J Gastrointest Surg 2005;9:869–877.CrossRefPubMed Dervenis C, Delis S, Avgerinos C, Madariaga J, Milicevic M. Changing concepts in the management of liver hydatid disease. J Gastrointest Surg 2005;9:869–877.CrossRefPubMed
21.
go back to reference Demirci S, Eraslan S, Anadol E, Bozatli L. Comparison of the results of different surgical techniques in the management of hydatid cysts of the liver. World J Surg 1989;13:88–91.CrossRefPubMed Demirci S, Eraslan S, Anadol E, Bozatli L. Comparison of the results of different surgical techniques in the management of hydatid cysts of the liver. World J Surg 1989;13:88–91.CrossRefPubMed
22.
go back to reference Safioleas M, Misiakos E, Manti C, Katsikas D, Skalkeas G. Diagnostic evaluation and surgical management of hydatid disease of the liver. World J Surg 1994;18:859–865.CrossRefPubMed Safioleas M, Misiakos E, Manti C, Katsikas D, Skalkeas G. Diagnostic evaluation and surgical management of hydatid disease of the liver. World J Surg 1994;18:859–865.CrossRefPubMed
23.
go back to reference Yagci G, Ustunsoz B, Kaymakcioglu N, Bozlar U, Gorgulu S, Simsek A, Akdeniz A, Cetiner S, Tufan T. Results of surgical, laparoscopic, and percutaneous treatment for hydatid disease of the liver: 10 years experience with 355 patients. World J Surg 2005;29:1670–1679.CrossRefPubMed Yagci G, Ustunsoz B, Kaymakcioglu N, Bozlar U, Gorgulu S, Simsek A, Akdeniz A, Cetiner S, Tufan T. Results of surgical, laparoscopic, and percutaneous treatment for hydatid disease of the liver: 10 years experience with 355 patients. World J Surg 2005;29:1670–1679.CrossRefPubMed
24.
go back to reference Bulbuller N, Ilhan YS, Kirkil C, Yeniçerioglu A, Ayten R, Cetinkaya Z. The results of surgical treatment for hepatic hydatid cysts in an endemic area. Turk J Gastroenterol 2006;17:273–278.PubMed Bulbuller N, Ilhan YS, Kirkil C, Yeniçerioglu A, Ayten R, Cetinkaya Z. The results of surgical treatment for hepatic hydatid cysts in an endemic area. Turk J Gastroenterol 2006;17:273–278.PubMed
25.
go back to reference El Malki HO, Dziri C, El Mejdoubi Y, Souadka A, Zakri B, Mohsine R, Ifrine L, Belkouchi A. Why fine-needle aspiration cytology is not an adequate diagnostic method for liver hydatid cyst. Arch Surg 2007;142:690. El Malki HO, Dziri C, El Mejdoubi Y, Souadka A, Zakri B, Mohsine R, Ifrine L, Belkouchi A. Why fine-needle aspiration cytology is not an adequate diagnostic method for liver hydatid cyst. Arch Surg 2007;142:690.
26.
27.
go back to reference El Malki HO, El Mejdoubi Y, Souadka Am, Mohsine R, Ifrine L, Abouqal R, Belkouchi A. Predictive model of biliocystic communication in liver hydatid cysts using classification and regression tree analysis. BMC Surg 2010;10:16. El Malki HO, El Mejdoubi Y, Souadka Am, Mohsine R, Ifrine L, Abouqal R, Belkouchi A. Predictive model of biliocystic communication in liver hydatid cysts using classification and regression tree analysis. BMC Surg 2010;10:16.
28.
go back to reference Maaouni A, Elalaoui M, Hamiani O, Benmansour A, Belkouchi A, Ahyoud F, Jalil A, Faik M. Chirurgie des kystes hydatiques du foie 581 patients. 952 kystes. Chirurgie 1989;115 Suppl 1:61–69. Maaouni A, Elalaoui M, Hamiani O, Benmansour A, Belkouchi A, Ahyoud F, Jalil A, Faik M. Chirurgie des kystes hydatiques du foie 581 patients. 952 kystes. Chirurgie 1989;115 Suppl 1:61–69.
29.
go back to reference Chautems R, Buhler L, Gold B, Chilcott M, Morel P, Mentha G. Long term results after complete or incomplete surgical resection of liver hydatid disease. Swiss Med Wkly 2003;133:258–262.PubMed Chautems R, Buhler L, Gold B, Chilcott M, Morel P, Mentha G. Long term results after complete or incomplete surgical resection of liver hydatid disease. Swiss Med Wkly 2003;133:258–262.PubMed
30.
go back to reference El Malki HO, El Mejdoubi Y, Mohsine R, Ifrine L, Belkouchi A. La rupture intraperitoneale du kyste hydatique du foie. Gastroenterol Clin Biol 2006;30:1214–1216. El Malki HO, El Mejdoubi Y, Mohsine R, Ifrine L, Belkouchi A. La rupture intraperitoneale du kyste hydatique du foie. Gastroenterol Clin Biol 2006;30:1214–1216.
31.
go back to reference Dziri C. Hydatid disease-continuing serious public health problem: introduction. World J Surg 2001;25:1–3.CrossRefPubMed Dziri C. Hydatid disease-continuing serious public health problem: introduction. World J Surg 2001;25:1–3.CrossRefPubMed
32.
go back to reference Michail OP, Georgiou C, Michail PO, Felekouras E, Karavokyros I, Marinos G, Giannopoulos A, Griniatsos J. Disappearance of recurrent intra-abdominal extrahepatic hydatid cyst following oral albendazole administration. West Indian Med J 2007;56:372–375.PubMed Michail OP, Georgiou C, Michail PO, Felekouras E, Karavokyros I, Marinos G, Giannopoulos A, Griniatsos J. Disappearance of recurrent intra-abdominal extrahepatic hydatid cyst following oral albendazole administration. West Indian Med J 2007;56:372–375.PubMed
33.
go back to reference WHO Informal Working Group on Echinococcosis. Guidelines for treatment of cystic and alveolar echinococcosis in humans. Bull World Health Organ 1996;74:231–242. WHO Informal Working Group on Echinococcosis. Guidelines for treatment of cystic and alveolar echinococcosis in humans. Bull World Health Organ 1996;74:231–242.
34.
go back to reference Dziri C, Haouet K, Zaouche A, et al. Comment traiter un kyste hydatique du foie non compliqué? Ann Chir 2005;130:249–251.CrossRefPubMed Dziri C, Haouet K, Zaouche A, et al. Comment traiter un kyste hydatique du foie non compliqué? Ann Chir 2005;130:249–251.CrossRefPubMed
35.
go back to reference Menezes da Silva A. Hydatid cyst of the liver-criteria for the selection of appropriate treatment. Acta Trop 2003;85:237–242. Menezes da Silva A. Hydatid cyst of the liver-criteria for the selection of appropriate treatment. Acta Trop 2003;85:237–242.
36.
go back to reference Wani RA, Malik AA, Chowdri NA, Wani KA, Naqash SH. Primary extrahepatic abdominal hydatidosis. Int J Surg 2005;3:125–127.CrossRefPubMed Wani RA, Malik AA, Chowdri NA, Wani KA, Naqash SH. Primary extrahepatic abdominal hydatidosis. Int J Surg 2005;3:125–127.CrossRefPubMed
37.
go back to reference Arif SH, Shams-Ul-Bari, Wani NA, Zargar SA, Wani MA, Tabassum R, Hussain Z, Baba AA, Lone RA. Albendazole as an adjuvant to the standard surgical management of hydatid cyst liver. Int J Surg 2008;6:448–451. Arif SH, Shams-Ul-Bari, Wani NA, Zargar SA, Wani MA, Tabassum R, Hussain Z, Baba AA, Lone RA. Albendazole as an adjuvant to the standard surgical management of hydatid cyst liver. Int J Surg 2008;6:448–451.
Metadata
Title
Does Primary Surgical Management of Liver Hydatid Cyst Influence Recurrence?
Authors
Hadj Omar El Malki
Yasser El Mejdoubi
Amine Souadka
Belkacem Zakri
Raouf Mohsine
Lahcen Ifrine
Redouane Abouqal
Abdelkader Belkouchi
Publication date
01-07-2010
Publisher
Springer-Verlag
Published in
Journal of Gastrointestinal Surgery / Issue 7/2010
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI
https://doi.org/10.1007/s11605-010-1220-0

Other articles of this Issue 7/2010

Journal of Gastrointestinal Surgery 7/2010 Go to the issue