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01-12-2009 | Original Article

Laparoscopic versus Open Liver Resection: A Matched-Pair Case Control Study

Authors: Kaori Ito, Hiromichi Ito, Chandrakanth Are, Peter J. Allen, Yuman Fong, Ronald P. DeMatteo, William R. Jarnagin, Michael I. D’Angelica

Published in: Journal of Gastrointestinal Surgery | Issue 12/2009

Abstract

Background

Laparoscopic liver resection (LLR) has become an increasingly popular operation; however, its theoretical benefits remain unproven. The aim of this study was to conduct a comparative outcome study between LLR and matched-pair open liver resections (OLR).

Methods

Sixty five patients underwent attempted LLR from 1998 through 2008; 52 of which were completed laparoscopically. Patients who underwent OLR prior to 1998 were matched to laparoscopic cases for demographics, comorbidities, diagnosis, tumor characteristics, procedure, and background liver. Perioperative and oncologic outcomes were compared between the two groups. Analyses were performed excluding and including conversion cases.

Results

Characteristics were comparable between both groups. LLR was associated with significant reductions in estimated blood loss, frequency of transfusion, frequency of Pringle maneuver, postoperative morbidity, time to recovery, length of hospital stay, and incidence of incisional hernia. For patients with malignant tumors, there were no positive surgical margins or local recurrence in either group and the overall pattern of recurrence was similar.

Conclusion

For well-selected patients, LLR is a feasible operation that does not compromise operative or oncologic outcomes. While LLR was associated with some benefits, these can only be definitively proven in a randomized controlled trial.

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Title: Laparoscopic versus Open Liver Resection: A Matched-Pair Case Control Study
Authors: Kaori Ito
Hiromichi Ito
Chandrakanth Are
Peter J. Allen
Yuman Fong
Ronald P. DeMatteo
William R. Jarnagin
Michael I. D’Angelica
Publication date: 01-12-2009
Publisher: Springer-Verlag
Published in: Journal of Gastrointestinal Surgery / Issue 12/2009
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI: https://doi.org/10.1007/s11605-009-0993-5

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Laparoscopic versus Open Liver Resection: A Matched-Pair Case Control Study

Abstract

Background

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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