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01-09-2008 | review article

Neoadjuvant Therapy for Pancreatic Cancer

Author: Andrew M. Lowy

Published in: Journal of Gastrointestinal Surgery | Issue 9/2008

Abstract

Surgical resection is necessary but generally insufficient as curative treatment for pancreatic cancer. Traditionally, postoperative (adjuvant) therapies have been utilized in an attempt to improve outcome, yet these efforts have met with extremely limited success. As preoperative (neoadjuvant) treatment strategies have evolved for the treatment of other malignancies, preoperative therapy for pancreatic cancer has been investigated by several groups over the past decade. At this time, no randomized trials comparing adjuvant and neoadjuvant therapies have been performed, nor have there been any large multicenter trials of neoadjuvant therapy for pancreatic cancer. In this manuscript, the rationale for neoadjuvant strategies are discussed in the context of the available data on both adjuvant and neoadjuvant therapy and clinical trials currently in development.

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Title: Neoadjuvant Therapy for Pancreatic Cancer
Author: Andrew M. Lowy
Publication date: 01-09-2008
Publisher: Springer-Verlag
Published in: Journal of Gastrointestinal Surgery / Issue 9/2008
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI: https://doi.org/10.1007/s11605-008-0482-2

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Neoadjuvant Therapy for Pancreatic Cancer

Abstract

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Abstract

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