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Journal of Gastrointestinal Surgery

Published in:

01-10-2007

Pancreatic Pseudocysts: Is Delayed Surgical Intervention Associated with Adverse Outcomes?

Authors: Kaori Ito, Alexander Perez, Hiromichi Ito, Edward E. Whang

Published in: Journal of Gastrointestinal Surgery | Issue 10/2007

Abstract

Background

Nonsurgical interventions are increasingly applied for pancreatic pseudocysts. We hypothesized that surgical therapy applied after failure of percutaneous or endoscopic therapies for pseudocysts is associated with poorer outcomes than cases in which surgery is the initial intervention.

Materials and methods

Medical records of all 284 patients admitted with pancreatic pseudocysts at our institution (1/1990–9/2005) were analyzed. Forty-six patients underwent surgery as the initial intervention (group A). Among 162 patients who underwent percutaneous or endoscopic drainage as the initial intervention, 75 patients required subsequent surgery after failure of nonsurgical intervention (group B).

Results

Groups were comparable in demographic variables and in location, number, and size of pseudocysts. Forty-two percent of group B patients developed infection within their pseudocysts after their nonsurgical interventions. Compared to group A patients, group B patients had higher rates of overall perioperative morbidity (47.8% vs 73.3%, p = 0.01) and postoperative readmission (24.0% vs 44.7%, p = 0.04). Five (6.7%) group B patients died in the perioperative period; there were no perioperative deaths among group A patients.

Conclusion

Delayed surgical intervention for pancreatic pseudocysts is associated with higher incidences of postoperative complications, readmission, morbidity, and mortality. The increasing application of nonsurgical interventions needs to be reevaluated.

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Title: Pancreatic Pseudocysts: Is Delayed Surgical Intervention Associated with Adverse Outcomes?
Authors: Kaori Ito
Alexander Perez
Hiromichi Ito
Edward E. Whang
Publication date: 01-10-2007
Publisher: Springer-Verlag
Published in: Journal of Gastrointestinal Surgery / Issue 10/2007
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI: https://doi.org/10.1007/s11605-007-0237-5

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Pancreatic Pseudocysts: Is Delayed Surgical Intervention Associated with Adverse Outcomes?

Abstract

Background

Materials and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Materials and methods

Results

Conclusion

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