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Japanese Journal of Radiology
Published in: Japanese Journal of Radiology 5/2018

01-05-2018 | Original Article

Brain-core temperature of patients before and after orthotopic liver transplantation assessed by DWI thermometry

Authors: Gianvincenzo Sparacia, Roberto Cannella, Vincenzina Lo Re, Giuseppe Mamone, Koji Sakai, Kei Yamada, Roberto Miraglia

Published in: Japanese Journal of Radiology | Issue 5/2018

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Abstract

Purpose

To assess brain-core temperature of end-stage liver disease patients undergoing orthotopic liver transplantation (OLT) using a temperature measurement technique based on the apparent diffusion coefficient of the cerebrospinal fluid in the lateral ventricles.

Materials and methods

The study group was composed of 19 patients with a model for end-stage liver disease (MELD) score of 23.7 who underwent MR imaging before and after OLT. MR imaging studies were performed with a 1.5T MR scanner. Brain-core temperature (T: °C) was calculated using the following equation from the apparent diffusion coefficient (D) of the cerebrospinal fluid in the lateral ventricles: \(T = {{2256.74} \mathord{\left/ {\vphantom {{2256.74} {\ln \left( {4.39221/D} \right)}}} \right. \kern-0pt} {\ln \left( {4.39221/D} \right)}}{-}273.15\) measured with a DWI sequence (b value 1000 s/mm2). We compared brain-core temperature of all patients before and after OLT.

Results

Brain-core temperature measurements were successfully taken in all patients before and after OLT. The measured brain-core temperature mean ± standard deviation was 38.67 ± 1.76 °C before OLT and 38.60 ± 0.99 °C after OLT, showing no significant difference (P = 0.643).

Conclusions

Brain-core temperature was stable in patients undergoing OLT. DWI thermometry may provide a supplementary brain biomarker to confirm that cerebral blood flow and metabolism are stable in patients undergoing OLT.
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Metadata
Title
Brain-core temperature of patients before and after orthotopic liver transplantation assessed by DWI thermometry
Authors
Gianvincenzo Sparacia
Roberto Cannella
Vincenzina Lo Re
Giuseppe Mamone
Koji Sakai
Kei Yamada
Roberto Miraglia
Publication date
01-05-2018
Publisher
Springer Japan
Published in
Japanese Journal of Radiology / Issue 5/2018
Print ISSN: 1867-1071
Electronic ISSN: 1867-108X
DOI
https://doi.org/10.1007/s11604-018-0729-0

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