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01-08-2015 | Original Article

Uterine artery embolization by use of porous gelatin particles for symptomatic uterine leiomyomas: comparison with hand-cut gelatin sponge particles

Authors: Yuichiro Izumi, Shuji Ikeda, Akira Kitagawa, Eisuke Katsuda, Makiyo Hagihara, Seiji Kamei, Toyohiro Ota, Tsuneo Ishiguchi

Published in: Japanese Journal of Radiology | Issue 8/2015

Abstract

Purpose

To evaluate the results of uterine artery embolization (UAE) for symptomatic uterine leiomyoma by use of porous gelatin particles (PGP) in comparison with conventional hand-cut gelatin sponge particles.

Materials and methods

One hundred and fifteen consecutive patients who had undergone UAE were retrospectively assessed. The first 64 patients were treated with hand-cut gelatin sponge and the last 51 with PGP. Extent of infarction, volume reduction of the dominant leiomyoma on magnetic resonance (MR) imaging, and change in symptoms were assessed.

Results

UAE was successfully performed for all patients. No major complications were observed. MR images one month after UAE showed that the mean extent of infarction of the dominant leiomyoma was 97 % for patients treated with PGP and 96 % for those treated with hand-cut gelatin sponge. Volume reductions of the dominant leiomyoma after 3, 6, 12, and 24 months were, respectively, 45, 56, 62, and 66 % for use of PGP and 45, 57, 63, and 68 % for use of hand-cut gelatin sponge. Symptoms including heavy menstrual bleeding, heavy menstrual pain, and abdominal heaviness had improved by 95–100 % at 12 months. There was no difference between the two groups.

Conclusion

UAE with PGP is safe, and as effective as conventional gelatin sponge particles.

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Title: Uterine artery embolization by use of porous gelatin particles for symptomatic uterine leiomyomas: comparison with hand-cut gelatin sponge particles
Authors: Yuichiro Izumi
Shuji Ikeda
Akira Kitagawa
Eisuke Katsuda
Makiyo Hagihara
Seiji Kamei
Toyohiro Ota
Tsuneo Ishiguchi
Publication date: 01-08-2015
Publisher: Springer Japan
Published in: Japanese Journal of Radiology / Issue 8/2015
Print ISSN: 1867-1071
Electronic ISSN: 1867-108X
DOI: https://doi.org/10.1007/s11604-015-0445-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Uterine artery embolization by use of porous gelatin particles for symptomatic uterine leiomyomas: comparison with hand-cut gelatin sponge particles

Abstract

Purpose

Materials and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Materials and methods

Results

Conclusion

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