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01-05-2012 | Original article

Characteristic magnetic resonance features of focal autoimmune pancreatitis useful for differentiation from pancreatic cancer

Authors: Yukiko Sugiyama, Yasunari Fujinaga, Masumi Kadoya, Kazuhiko Ueda, Masahiro Kurozumi, Hideaki Hamano, Shigeyuki Kawa

Published in: Japanese Journal of Radiology | Issue 4/2012

Abstract

Purpose

To identify characteristic magnetic resonance (MR) features of focal autoimmune pancreatitis (f-AIP) useful for differentiation from pancreatic cancer (PC).

Methods

We retrospectively analyzed MR imaging findings of 20 f-AIP lesions and 40 PC lesions smaller than 40 mm in diameter. On fat-suppressed T2-weighted images and dynamic contrast-enhanced fat-suppressed T1-weighted images (DCE-T1WI), we classified MR features of internal signal intensity for each lesion into homogeneous, speckled, or target type. We assessed the sensitivity, specificity, and accuracy of these findings in the diagnosis of f-AIP. We also investigated the incidence of previously reported findings for differentiation between f-AIP and PC.

Results

Speckled enhancement within a hypointense or isointense lesion on pancreatic phase DCE-T1WI (speckled type) was observed more frequently in f-AIP than in PC, with high sensitivity, high specificity, and high accuracy. Hypointensity to hyperintensity surrounding a less enhanced focal area on DCE-T1WIs (target type) and upper stream main pancreatic duct dilatation were observed more frequently in PC than in f-AIP.

Conclusion

Speckled enhancement inside an f-AIP lesion on pancreatic phase DCE-T1WI was useful for differentiation from PC.

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Title: Characteristic magnetic resonance features of focal autoimmune pancreatitis useful for differentiation from pancreatic cancer
Authors: Yukiko Sugiyama
Yasunari Fujinaga
Masumi Kadoya
Kazuhiko Ueda
Masahiro Kurozumi
Hideaki Hamano
Shigeyuki Kawa
Publication date: 01-05-2012
Publisher: Springer Japan
Published in: Japanese Journal of Radiology / Issue 4/2012
Print ISSN: 1867-1071
Electronic ISSN: 1867-108X
DOI: https://doi.org/10.1007/s11604-011-0047-2

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Characteristic magnetic resonance features of focal autoimmune pancreatitis useful for differentiation from pancreatic cancer

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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