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HAND
Published in: HAND 1/2015

01-03-2015

Phenolization and coralline hydroxyapatite grafting following meticulous curettage for the treatment of enchondroma of the hand. A case series of 82 patients with 5-year follow-up

Authors: Dimitrios Georgiannos, Vasilios Lampridis, Ilias Bisbinas

Published in: HAND | Issue 1/2015

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Abstract

Background

Enchondromas are benign cartilaginous tumours. The most common location is in the long bones of the hand. Treatment methods fall into a broad spectrum ranging from conservative, medical therapies, to a variety of surgical procedures, which may or may not employ the use of local adjuvant treatment or bone grafting. The purpose of this study was to report our experience and evaluate the long-term results of patients with enchondroma of the hand, treated in our department with meticulous curettage, phenolization and coralline hydroxyapatite grafting.

Methods

We present 82 patients with hand enchondromas treated surgically in our department during the last 10 years. The patients were treated operatively with meticulous curettage of the bone lesion, with use of phenol 5 % as local adjuvant and coralline hydroxyapatite bone graft to fill in the remaining cavity.

Results

At a minimum of 5-year follow-up, radiographs and clinical examination showed adequate bone formation at the site of enchondroma excavation and no evidence of recurrence, fracture, infection or other complication related to the procedure.

Conclusion

We concluded that the combination of meticulous curettage of the lesion, with the use of phenol as local adjuvant and coralline hydroxyapatite graft is a safe technique that prevents recurrence and allows adequate and uncomplicated local new bone formation.
Literature
1.
Bickels J, Meller I, Shmookler BM, Malawer MM. The role and biology of cryosurgery in the treatment of bone tumors. A review. Acta Orthop Scand. 1999;70(3):308–15.CrossRefPubMed
2.
Bickels J, Wittig JC, Kollendes Y, et al. Enchondromas of the hand: treatment with curettage and cemented internal fixation. J Hand Surg. 2002;27A:870–5.CrossRef
3.
Brien EW, Mirra JM, Kerr R. Benign and malignant cartilage tumors of bone and joint: their anatomic and theoretical basis with emphasis on radiology, pathology and clinical biology. The intramedullary cartilage tumors. Skelet Radiol. 1997;26:325–53.CrossRef
4.
Damien E, Revell P. Coralline hydroxyapatite bone graft substitute: a review of experimental studies and biomedical applications. J Applied Biomater & Biomech. 2004;2:65–73.
5.
Durr HR, Maier M, Jansson V, Refior HJ. Phenol as an adjuvant for local control in the treatment of giant cell tumour of the bone. Eur J Surg Oncol. 1999;25(6):610–8.CrossRefPubMed
6.
Enneking W, Dunham W, Gebhardt M, Malawar M, Pritchard D. A system for the functional evaluation of reconstructive procedures after surgical treatment of tumors of the musculoskeletal system. Clin Orthop Relat Res. 1993;286:241–6.PubMed
7.
Etchebehere M, de Camargo OP, Croci AT, Oliveira CR, Baptista AM. Relationship between surgical procedure and outcome for patients with grade I chondrosarcomas Clinics (Sao Paolo) 2005; 60:121–6.
8.
Figl M, Leixnering M. Retrospective review of outcome after surgical treatment of enchondromas in the hand. Arch Orthop Trauma Surg. 2009;129:729–34.CrossRefPubMed
9.
Flemming D, Murphey M. Enchondroma and chondrosarcoma. Seminars in musculoskeletal radiology. 2000, Vol.4, No 1.
10.
Gaasbeek RDA, Rijnberg WJ, van Loon CJM, Meyers H, Feith R. No local recurrence of enchondroma after curettage and plaster filling. Arch Orthop Trauma Surg. 2005;125:42–5.CrossRefPubMed
11.
Giles DW, Miller SJ, Rayan GM. Adjunctive treatment of enchondromas with CO2 Laser. Lasers Surg Med. 1999;24:187–93.CrossRefPubMed
12.
Hasselgreen G, Forssblad P, Tornvall A. Bone grafting unnecessary in the treatment of enchondromas in the hand. J Hand Surg. 1991;16A:139–42.CrossRef
13.
Irwin RB, Bernhard M, Biddinger A. Coralline hydroxyapatite as bone substitute in orthopedic oncology. Am J Orthop. 2001;30(7):544–50.PubMed
14.
Jewusiak EM, Spence KF, Sell KW. Solitary benign enchondroma of the long bones of the hand. J Bone Joint Surg. 1971;53A:1587–90.
15.
Joosten U, Joist A, Frebel T, Walter M, Langer M. The use of an in situ curing hydroxyapatite cement as an alternative to bone graft following removal of enchondroma of the hand. J Hand Surg (Br). 2000;25(3):288–91.CrossRef
16.
Kim JK, Kim NK. Curettage and calcium phosphate bone cement injection for the treatment of enchondroma of the finger. Hand Surg. 2012;17(1):65–70.CrossRefPubMed
17.
Leerapun T, Hugate RR, Inwards CY, Scully SP, Sim FH. Surgical management of conventional grade I chondrosarcoma of long bones. Clin Orthop Relat Res. 2007;463:166–72.PubMed
18.
Machens HG, Brenner P, Wienbergen H, et al. Enchondroma of the hand. Clinical evaluation study of diagnosis, surgery, and functional outcome. Unfallchirurg. 1997;100:711–4.CrossRefPubMed
19.
Malawer MM, Bickels J, Meller I, Buch RG, Henshaw RM, Kollender Y. Cryosurgery in the treatment of giant cell tumors. a long term followup study. Clin Orthop Relat Res. 1999;359:176–88.CrossRefPubMed
20.
Mankin HJ, Gebhardt MC, Jennings LC, Springfield DS, Tomford WW. Long term results of allograft replacement in the management of bone tumors. Clin Orthop. 1996;324:86–97.CrossRefPubMed
21.
Mankin HJ. Chondrosarcoma of bone. In: Menendez LR, editor. Orthopaedic knowledge update: musculoskeletal tumors. Rosemont: American Academy of Orthopaedic Surgeons; 2002. p. 187–94.
22.
Marco R, Gitelis S, Brebach G, Healey J. Cartilage tumors: evaluation and treatment. J Am Acad Orthop Surg. 2000;8(5):292–304.PubMed
23.
Marcove RC. A 17 year review of cryosurgery in the treatment of bone tumours. Clin Orthop Relat Res. 1977;122:147–56.PubMed
24.
Mirra JM, Gold R, Eckardt JJ. A new histologic approach to the differentiation of enchondroma and chondrosarcoma of the bones. Clin Orthop. 1985;201:214–37.PubMed
25.
Mohler D, Chiu R, McCall D, Avedian R. Curettage and cryosurgery for low-grade cartilage tumors is associated with low recurrence and high function. Clin Orthop Relat Res. 2010;468:2765–73.CrossRefPubMedPubMedCentral
26.
Quint U, Muller RT, Muller G. Characteristics of phenol. Instillation in intralesional tumor excision of chondroblastoma, osteoclastoma and enchondroma. Arch Orthop Trauma Surg. 1998;117:43–6.CrossRefPubMed
27.
Resnick D, Kyriakos M, Greenway GD. Tumors and tumor-like lesions of bone: imaging and pathology of specific lesions. Diagnosis of bone and joint disorders. 3rd ed. Philadelphia: WB Saunders; 1995. p. 3628–938.
28.
Samman PD. Enchondroma with fracture through the distal phalanx. Clin Exp Dermatol. 1980;10:85–6.CrossRef
29.
Sanerkin NG, Gallagher P. A review of the behaviour of chondrosarcoma of bone. J Bone Joint Surg. 1979;61B:395–400.
30.
Sekiya I, Matsui N, Otsuka T, Kobayashi M, Tsuchiya D. The treatment of enchondromas in the hand by endoscopic curettage without bone grafting. J Hand Surg. 1997;22B:230–4.CrossRef
31.
Shenoy R, Pillai A, Reid R. Tumours of the hand presenting as pathological fractures. Acta Orthop Belg. 2007;73:192–5.PubMed
32.
Tomford WW. Transmission of disease through transplantation of musculoskeletal allografts. J Bone Joint Surg. 1995;77A:1742–54.
33.
Yanagawa T, Watanabe H, Shinozaki T, Takagishi K. Curettage of benign bone tumors without grafts gives sufficient bone strength. Acta Orthop. 2009;80(1):9–13.CrossRefPubMedPubMedCentral
34.
Yasuda M, Masada K, Takeuchi E. Treatment of enchondroma of the hand with injectable calcium phosphate bone cement. J Hand Surg. 2006;31A:98–102.CrossRef
Metadata
Title
Phenolization and coralline hydroxyapatite grafting following meticulous curettage for the treatment of enchondroma of the hand. A case series of 82 patients with 5-year follow-up
Authors
Dimitrios Georgiannos
Vasilios Lampridis
Ilias Bisbinas
Publication date
01-03-2015
Publisher
Springer US
Published in
HAND / Issue 1/2015
Print ISSN: 1558-9447
Electronic ISSN: 1558-9455
DOI
https://doi.org/10.1007/s11552-014-9674-2

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