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Published in: La radiologia medica 11/2019

01-11-2019 | Magnetic Resonance Imaging | MAGNETIC RESONANCE IMAGING

New advances in MRI diagnosis of degenerative osteoarthropathy of the peripheral joints

Authors: Federico Bruno, Francesco Arrigoni, Pierpaolo Palumbo, Raffaele Natella, Nicola Maggialetti, Alfonso Reginelli, Alessandra Splendiani, Ernesto Di Cesare, Luca Brunese, Giuseppe Guglielmi, Andrea Giovagnoni, Carlo Masciocchi, Antonio Barile

Published in: La radiologia medica | Issue 11/2019

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Abstract

Degenerative osteoarthropathy is one of the leading causes of the pain and disability from musculoskeletal disease in the adult population. Magnetic resonance imaging (MRI) allows optimal visualization of all tissues involved in degenerative osteoarthritis disease process, mainly the articular cartilage. In addition to qualitative and semiquantitative morphologic assessment, several MRI-based advanced techniques have been developed to allow characterization and quantification of the biochemical cartilage composition. These include quantitative analysis and several compositional techniques (T1 and T2 relaxometry measurements and mapping, sodium imaging, delayed gadolinium-enhanced MRI of cartilage dGEMRIC, glycosaminoglycan-specific chemical exchange saturation transfer gagCEST, diffusion-weighted imaging DWI and diffusion tensor imaging DTI). These compositional MRI techniques may have the potential to serve as quantitative, reproducible, noninvasive and objective endpoints for OA assessment, particularly in diagnosis of early and pre-radiographic stages of the disease and in monitoring disease progression and treatment effects over time.
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Metadata
Title
New advances in MRI diagnosis of degenerative osteoarthropathy of the peripheral joints
Authors
Federico Bruno
Francesco Arrigoni
Pierpaolo Palumbo
Raffaele Natella
Nicola Maggialetti
Alfonso Reginelli
Alessandra Splendiani
Ernesto Di Cesare
Luca Brunese
Giuseppe Guglielmi
Andrea Giovagnoni
Carlo Masciocchi
Antonio Barile
Publication date
01-11-2019
Publisher
Springer Milan
Published in
La radiologia medica / Issue 11/2019
Print ISSN: 0033-8362
Electronic ISSN: 1826-6983
DOI
https://doi.org/10.1007/s11547-019-01003-1

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