Skip to main content
Top
Published in: La radiologia medica 8/2016

01-08-2016 | CARDIAC RADIOLOGY

320-row coronary computed tomography angiography (CCTA) with automatic exposure control (AEC): effect of 100 kV versus 120 kV on image quality and dose exposure

Authors: Ernesto Di Cesare, Antonio Gennarelli, Alessandra Di Sibio, Valentina Felli, Marco Perri, Alessandra Splendiani, Giovanni Luca Gravina, Antonio Barile, Carlo Masciocchi

Published in: La radiologia medica | Issue 8/2016

Login to get access

Abstract

Purpose

To compare the impact of a 100 kV tube voltage protocol to 120 kV in terms of image quality and radiation dose by a 320 row coronary computed tomography angiography (CCTA) with automatic exposure control (AEC).

Materials and methods

Using a propensity matched analysis we compared a group of 135 patients scanned using a 100 kV tube voltage protocol with a group of 135 subjects scanned employing a 120 kV tube voltage setting. In all subjects the heart rate (HR) was <65 bpm and all CT scans were acquired using a prospective ECG gating and AEC strategy. Mean effective radiation dose and subjective and objective (Noise or N, signal to noise ratio or SNR, contrast to noise ratio or CNR) image quality, were evaluated. Subjective quality was assessed by two experienced radiologists using a 5-point scale (0: non diagnostic—4: excellent) using the 15-segment American Heart Association (AHA) coronary artery classification.

Results

Mean effective dose and noise were non significantly different between the two groups: mean effective dose was 2.89 ± 0.7 mSv in the 100 kV group and 2.80 ± 0.57 mSv in the 120 kV group (p = 0.25) while noise was 28.9 ± 3.3 in the 120 kV group and 29.05 ± 3.6 in the 100 kV group (p = 0.72). Both SNR and CNR were significantly higher in the 100 kV group than in the 120 kV group. This data agrees with the evidence that subjective quality was significantly higher in the 100 kV group in the middle and distal segmental classes.

Conclusion

Our study shows that, in using a 320 row CCTA with AEC strategy it is better to employ a 100 kV tube voltage protocol because compared to 120 kV tube voltage setting, it appears to significantly improve both subjective and objective image quality without decreasing the mean effective radiation dose.
Literature
1.
go back to reference Lloyd-Jones D, Adams RJ, Brown TM, Carnethon M, Dai S, De Simone G, Ferguson TB, Ford E, Furie K, Gillespie C, Go A, Greenlund K, Haase N, Hailpern S, Ho PM, Howard V, Kissela B, Kittner S, Lackland D, Lisabeth L, Marelli A, McDermott MM, Meigs J, Mozaffarian D, Mussolino M, Nichol G, Roger VL, Rosamond W, Sacco R, Sorlie P, Stafford R, Thom T, Wasserthiel-Smoller S, Wong ND, Wylie-Rosett J, American Heart Association Statistics Committee and Stroke Statistics Subcommittee (2010) Executive summary: heart disease and stroke statistics – 2010 update: a report from the American Heart Association. Circulation. 121(7):948–954. doi:10.1161/CIRCULATIONAHA.109.192666 CrossRefPubMed Lloyd-Jones D, Adams RJ, Brown TM, Carnethon M, Dai S, De Simone G, Ferguson TB, Ford E, Furie K, Gillespie C, Go A, Greenlund K, Haase N, Hailpern S, Ho PM, Howard V, Kissela B, Kittner S, Lackland D, Lisabeth L, Marelli A, McDermott MM, Meigs J, Mozaffarian D, Mussolino M, Nichol G, Roger VL, Rosamond W, Sacco R, Sorlie P, Stafford R, Thom T, Wasserthiel-Smoller S, Wong ND, Wylie-Rosett J, American Heart Association Statistics Committee and Stroke Statistics Subcommittee (2010) Executive summary: heart disease and stroke statistics – 2010 update: a report from the American Heart Association. Circulation. 121(7):948–954. doi:10.​1161/​CIRCULATIONAHA.​109.​192666 CrossRefPubMed
2.
go back to reference Einstein AJ, Henzlova MJ, Rajagopalan S (2007) Estimating risk of cancer associated with radiation exposure from 64-slice computed tomography coronary angiography. JAMA 298(3):317–23 Einstein AJ, Henzlova MJ, Rajagopalan S (2007) Estimating risk of cancer associated with radiation exposure from 64-slice computed tomography coronary angiography. JAMA 298(3):317–23
3.
go back to reference Di Cesare E, Gennarelli A, Di Sibio A, Felli V, Splendiani A, Gravina GL, Barile A, Masciocchi C (2014) Assessment of dose exposure and image quality in coronary angiography performed by 640-slice CT: a comparison between adaptive iterative and filtered back-projection algorithm by propensity analysis. Radiol Med 119(8):642–649. doi:10.1007/s11547-014-0382-3 CrossRefPubMed Di Cesare E, Gennarelli A, Di Sibio A, Felli V, Splendiani A, Gravina GL, Barile A, Masciocchi C (2014) Assessment of dose exposure and image quality in coronary angiography performed by 640-slice CT: a comparison between adaptive iterative and filtered back-projection algorithm by propensity analysis. Radiol Med 119(8):642–649. doi:10.​1007/​s11547-014-0382-3 CrossRefPubMed
4.
go back to reference Di Cesare E, Carbone I, Carriero A, Centonze M, De Cobelli F, De Rosa R, Di Renzi P, Esposito A, Faletti R, Fattori R, Francone M, Giovagnoni A, La Grutta L, Ligabue G, Lovato L, Marano R, Midiri M, Natale L, Romagnoli A, Russo V, Sardanelli F, Cademartiri F; Working Group of the Cardiac Radiology Section of the Italian Society of Medical Radiology (SIRM) (2012) Clinical indications for cardiac computed tomography. From the Working Group of the Cardiac Radiology Section of the Italian Society of Medical Radiology (SIRM). Rad Med 117(6):901–938 Di Cesare E, Carbone I, Carriero A, Centonze M, De Cobelli F, De Rosa R, Di Renzi P, Esposito A, Faletti R, Fattori R, Francone M, Giovagnoni A, La Grutta L, Ligabue G, Lovato L, Marano R, Midiri M, Natale L, Romagnoli A, Russo V, Sardanelli F, Cademartiri F; Working Group of the Cardiac Radiology Section of the Italian Society of Medical Radiology (SIRM) (2012) Clinical indications for cardiac computed tomography. From the Working Group of the Cardiac Radiology Section of the Italian Society of Medical Radiology (SIRM). Rad Med 117(6):901–938
5.
go back to reference Di Cesare E, Gennarelli A, Di Sibio A, Felli V, Splendiani A, Gravina GL, Masciocchi C (2015). Image quality and radiation dose of single heartbeat 640-slice coronary CT angiography: A comparison between patients with chronic Atrial Fibrillation and subjects in normal sinus rhythm by propensity analysis. Eur J Radiol 84(4): 631–636. doi: 10.1016/j.ejrad.2014.11.035 Di Cesare E, Gennarelli A, Di Sibio A, Felli V, Splendiani A, Gravina GL, Masciocchi C (2015). Image quality and radiation dose of single heartbeat 640-slice coronary CT angiography: A comparison between patients with chronic Atrial Fibrillation and subjects in normal sinus rhythm by propensity analysis. Eur J Radiol 84(4): 631–636. doi: 10.1016/j.ejrad.2014.11.035
6.
go back to reference Lee CH, Goo JM, Ye HJ, Ye SJ, Park CM, Chun EJ, Im JG (2008) Radiation dose modulationtechniques in the multidetector CT era: from basics to practice. Radiographics 28(5):1451–1459. doi: 10.1148/rg.285075075 Lee CH, Goo JM, Ye HJ, Ye SJ, Park CM, Chun EJ, Im JG (2008) Radiation dose modulationtechniques in the multidetector CT era: from basics to practice. Radiographics 28(5):1451–1459. doi: 10.1148/rg.285075075
7.
go back to reference Austen WG, Edwards JE, Frye RL, Gensini GG, Gott VL, Griffith LS, McGoon DC, Murphy ML, Roe BB (1975). A reporting system on patients evaluated for coronary artery disease. Report of the Ad Hoc Committee for Grading of Coronary Artery Disease, Council on Cardiovascular Surgery, American Heart Association. Circulation 51(4 Suppl):5–40 Austen WG, Edwards JE, Frye RL, Gensini GG, Gott VL, Griffith LS, McGoon DC, Murphy ML, Roe BB (1975). A reporting system on patients evaluated for coronary artery disease. Report of the Ad Hoc Committee for Grading of Coronary Artery Disease, Council on Cardiovascular Surgery, American Heart Association. Circulation 51(4 Suppl):5–40
8.
go back to reference Leipsic J, Labounty TM, Heilbron B, Min JK, Mancini GB, Lin FY, Taylor C, Dunning A, Earls JP (2010) Adaptive statistical iterative reconstruction: assessment of image noise and image quality in coronary CT angiography. AJR Am J Roentgenol 195(3):649–654. doi:10.2214/AJR.10.4285 CrossRefPubMed Leipsic J, Labounty TM, Heilbron B, Min JK, Mancini GB, Lin FY, Taylor C, Dunning A, Earls JP (2010) Adaptive statistical iterative reconstruction: assessment of image noise and image quality in coronary CT angiography. AJR Am J Roentgenol 195(3):649–654. doi:10.​2214/​AJR.​10.​4285 CrossRefPubMed
9.
go back to reference Park EA, Lee W, Kim KW, Kim KG, Thomas A, Chung JW, Park JH (2012) Iterative reconstruction of dual-source coronary CT angiography: assessment of image quality and radiation dose. Int J Cardiovasc Imaging 28(7):1775–1786. doi:10.1007/s10554-011-0004-2 CrossRefPubMed Park EA, Lee W, Kim KW, Kim KG, Thomas A, Chung JW, Park JH (2012) Iterative reconstruction of dual-source coronary CT angiography: assessment of image quality and radiation dose. Int J Cardiovasc Imaging 28(7):1775–1786. doi:10.​1007/​s10554-011-0004-2 CrossRefPubMed
10.
go back to reference Chun EJ, Lee W, Choi YH, Koo BK, Choi SI, Jae HJ, Kim HC, So YH, Chung JW, Park JH (2008) Effects of nitroglycerin on the diagnostic accuracy of electrocardiogram-gated coronary computed tomography angiography. J Comput Assist Tomogr 32(1):86–92. doi: 10.1097/rct.0b013e318059befa Chun EJ, Lee W, Choi YH, Koo BK, Choi SI, Jae HJ, Kim HC, So YH, Chung JW, Park JH (2008) Effects of nitroglycerin on the diagnostic accuracy of electrocardiogram-gated coronary computed tomography angiography. J Comput Assist Tomogr 32(1):86–92. doi: 10.1097/rct.0b013e318059befa
11.
go back to reference Bittencourt MS, Schmidt B, Seltmann M, Muschiol G, Ropers D, Daniel WG, Achenbach S (2011) Iterative reconstruction in image space (IRIS) in cardiac computed tomography: initial experience. Int J Cardiovasc Imaging 27:1081–1087.doi: 10.1007/s10554-010-9756-3 Bittencourt MS, Schmidt B, Seltmann M, Muschiol G, Ropers D, Daniel WG, Achenbach S (2011) Iterative reconstruction in image space (IRIS) in cardiac computed tomography: initial experience. Int J Cardiovasc Imaging 27:1081–1087.doi: 10.1007/s10554-010-9756-3
12.
go back to reference Yoo RE, Park EA, Lee W, Shim H, Kim YK, Chung JW, Park JH (2013) Image quality of adaptive iterative dose reduction 3D of coronary CT angiography of 640-slice CT: comparison with filtered back-projection. Int J Cardiovasc Imaging 29(3):669–676. doi:10.1007/s10554-012-0113-6 CrossRefPubMed Yoo RE, Park EA, Lee W, Shim H, Kim YK, Chung JW, Park JH (2013) Image quality of adaptive iterative dose reduction 3D of coronary CT angiography of 640-slice CT: comparison with filtered back-projection. Int J Cardiovasc Imaging 29(3):669–676. doi:10.​1007/​s10554-012-0113-6 CrossRefPubMed
13.
go back to reference Hara AK, Paden RG, Silva AC, Kujak JL, Lawder HJ, Pavlicek W (2009) Iterative reconstruction technique for reducing body radiation dose at CT: feasibility study. AJR Am J Roentgenol 193(3):764–771. doi: 10.2214/AJR.09.2397 Hara AK, Paden RG, Silva AC, Kujak JL, Lawder HJ, Pavlicek W (2009) Iterative reconstruction technique for reducing body radiation dose at CT: feasibility study. AJR Am J Roentgenol 193(3):764–771. doi: 10.2214/AJR.09.2397
14.
go back to reference Bongartz G, Golding SJ, Jurik AG et al (2004). European Guidelines for Multislice Computed Tomography. Funded by the European Commission; EUR 16262 EN Bongartz G, Golding SJ, Jurik AG et al (2004). European Guidelines for Multislice Computed Tomography. Funded by the European Commission; EUR 16262 EN
15.
go back to reference Rubin DB (1997) Estimating causal effects from large data sets using propensity scores. Ann Intern Med 127(8 Pt 2):757–763CrossRefPubMed Rubin DB (1997) Estimating causal effects from large data sets using propensity scores. Ann Intern Med 127(8 Pt 2):757–763CrossRefPubMed
16.
go back to reference Cohen J (1960) A coefficient of agreement for nominal scales. EducPsycholMeas 20:37–46 Cohen J (1960) A coefficient of agreement for nominal scales. EducPsycholMeas 20:37–46
17.
go back to reference Bischoff B, Hein F, Meyer T, Hadamitzky M, Martinoff S, Schoemig A, Hausleiter J (2009) Impact of a reduced tube voltage on CT angiography and radiation dose: results of the protection I study. JACC Cardiovasc Imaging 2(8):940–946CrossRefPubMed Bischoff B, Hein F, Meyer T, Hadamitzky M, Martinoff S, Schoemig A, Hausleiter J (2009) Impact of a reduced tube voltage on CT angiography and radiation dose: results of the protection I study. JACC Cardiovasc Imaging 2(8):940–946CrossRefPubMed
18.
go back to reference Leschka S, Stolzmann P, Schmid FT, Scheffel H, Stinn B, Marincek B, Alkadhi H, Wildermuth S (2008) Low kilovoltage cardiac dual-source CT: attenuation, noise, and radiation dose. EurRadiol 18(9):1809–1817 Leschka S, Stolzmann P, Schmid FT, Scheffel H, Stinn B, Marincek B, Alkadhi H, Wildermuth S (2008) Low kilovoltage cardiac dual-source CT: attenuation, noise, and radiation dose. EurRadiol 18(9):1809–1817
19.
go back to reference Zhang C, Zhang Z, Yan Z, Xu L, Yu W, Wang R (2011) 320-row CT coronary angiography: effect of 100-kV tube voltages on image quality, contrast volume, and radiation dose. Int J Cardiovasc Imaging 27:1059–1068. doi:10.1007/s10554-010-9754-5 CrossRefPubMed Zhang C, Zhang Z, Yan Z, Xu L, Yu W, Wang R (2011) 320-row CT coronary angiography: effect of 100-kV tube voltages on image quality, contrast volume, and radiation dose. Int J Cardiovasc Imaging 27:1059–1068. doi:10.​1007/​s10554-010-9754-5 CrossRefPubMed
20.
go back to reference Alkadhi H, Stolzmann P, Scheffel H, Desbiolles L, Baumuller S, Plass A, Genoni M, Marincek B, Leschka S (2008) Radiation dose of cardiac dual-source ct: the effect of tailoring the protocol to patient-specific parameters. Eur J Radiol 68(3):385–391. doi:10.1016/j.ejrad.2008.08.015 CrossRefPubMed Alkadhi H, Stolzmann P, Scheffel H, Desbiolles L, Baumuller S, Plass A, Genoni M, Marincek B, Leschka S (2008) Radiation dose of cardiac dual-source ct: the effect of tailoring the protocol to patient-specific parameters. Eur J Radiol 68(3):385–391. doi:10.​1016/​j.​ejrad.​2008.​08.​015 CrossRefPubMed
21.
go back to reference Blankstein R, Bolen MA, Pale R, Murphy MK, Shah AB, Bezerra HG, Sarwar A, Rogers IS, Hoffmann U, Abbara S, Cury RC, Brady TJ (2011) Use of 100 kV versus 120 kV in cardiac dual source computed tomography: effect on radiation dose and image quality. Int J Cardiovasc Imaging 27:579–586. doi:10.1007/s10554-010-9683-3 CrossRefPubMed Blankstein R, Bolen MA, Pale R, Murphy MK, Shah AB, Bezerra HG, Sarwar A, Rogers IS, Hoffmann U, Abbara S, Cury RC, Brady TJ (2011) Use of 100 kV versus 120 kV in cardiac dual source computed tomography: effect on radiation dose and image quality. Int J Cardiovasc Imaging 27:579–586. doi:10.​1007/​s10554-010-9683-3 CrossRefPubMed
22.
go back to reference Szucs-Farkas Z, Verdun FR, von Allmen G, Mini RL, Vock P (2008) Effect of X-ray tube parameters, iodine concentration, and patient size on image quality in pulmonary computed tomography angiography: a chest-phantom-study. Invest Radiol 43(6):374–381. doi:10.1097/RLI.0b013e3181690042 CrossRefPubMed Szucs-Farkas Z, Verdun FR, von Allmen G, Mini RL, Vock P (2008) Effect of X-ray tube parameters, iodine concentration, and patient size on image quality in pulmonary computed tomography angiography: a chest-phantom-study. Invest Radiol 43(6):374–381. doi:10.​1097/​RLI.​0b013e3181690042​ CrossRefPubMed
23.
go back to reference Cademartiri F, Mollet NR, Lemos PA et al (2006) Higher intracoronary attenuation improves diagnostic accuracy in MDCT coronary angiography. AJR Am J Roentgenol 187:W430–W433CrossRefPubMed Cademartiri F, Mollet NR, Lemos PA et al (2006) Higher intracoronary attenuation improves diagnostic accuracy in MDCT coronary angiography. AJR Am J Roentgenol 187:W430–W433CrossRefPubMed
24.
go back to reference LaGrutta L, Galia M, Gentile G et al (2013) Comparison of iodinated contrast media for the assessment of atherosclerotic plaque attenuation values by CT coronary angiography: observations in an ex vivo model. Br J Radiol 86:20120238. doi:10.1259/bjr.20120238 CrossRef LaGrutta L, Galia M, Gentile G et al (2013) Comparison of iodinated contrast media for the assessment of atherosclerotic plaque attenuation values by CT coronary angiography: observations in an ex vivo model. Br J Radiol 86:20120238. doi:10.​1259/​bjr.​20120238 CrossRef
25.
go back to reference Cademartiri F, La Grutta L, Palumbo A et al (2007) Imaging techniques for the vulnerable coronary plaque. Radiol Med. 112(5):637–659CrossRefPubMed Cademartiri F, La Grutta L, Palumbo A et al (2007) Imaging techniques for the vulnerable coronary plaque. Radiol Med. 112(5):637–659CrossRefPubMed
26.
go back to reference Makaryus JN, Makaryus AN (2009) Coronary calcification: Achilles’ heel in the assessment for coronary artery disease in patients with symptomatic angina? Int J Cardiovasc Imaging 25(8): 855–857. doi: 10.1007/s10554-009-9535-1 Makaryus JN, Makaryus AN (2009) Coronary calcification: Achilles’ heel in the assessment for coronary artery disease in patients with symptomatic angina? Int J Cardiovasc Imaging 25(8): 855–857. doi: 10.1007/s10554-009-9535-1
Metadata
Title
320-row coronary computed tomography angiography (CCTA) with automatic exposure control (AEC): effect of 100 kV versus 120 kV on image quality and dose exposure
Authors
Ernesto Di Cesare
Antonio Gennarelli
Alessandra Di Sibio
Valentina Felli
Marco Perri
Alessandra Splendiani
Giovanni Luca Gravina
Antonio Barile
Carlo Masciocchi
Publication date
01-08-2016
Publisher
Springer Milan
Published in
La radiologia medica / Issue 8/2016
Print ISSN: 0033-8362
Electronic ISSN: 1826-6983
DOI
https://doi.org/10.1007/s11547-016-0643-4

Other articles of this Issue 8/2016

La radiologia medica 8/2016 Go to the issue