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01-07-2013 | Case Report

SPME–GC–MS analysis of α-pyrrolidinovaleorophenone in blood in a fatal poisoning case

Authors: Takeshi Saito, Akira Namera, Motoki Osawa, Hiromichi Aoki, Sadaki Inokuchi

Published in: Forensic Toxicology | Issue 2/2013

Abstract

We provided toxicological analytical support for a fatal case of abuse of α-pyrrolidinovaleorophenone (α-PVP). Solid-phase microextraction (SPME) and capillary gas chromatography coupled to mass spectrometry (GC–MS) was employed to quantify the drug in whole blood. The whole blood concentration of the drug in the heart was 486 ng/ml. This is the first report of α-PVP intoxication as ascertained by mass spectrometric identification of α-PVP in whole blood.

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Title: SPME–GC–MS analysis of α-pyrrolidinovaleorophenone in blood in a fatal poisoning case
Authors: Takeshi Saito
Akira Namera
Motoki Osawa
Hiromichi Aoki
Sadaki Inokuchi
Publication date: 01-07-2013
Publisher: Springer Japan
Published in: Forensic Toxicology / Issue 2/2013
Print ISSN: 1860-8965
Electronic ISSN: 1860-8973
DOI: https://doi.org/10.1007/s11419-013-0183-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

SPME–GC–MS analysis of α-pyrrolidinovaleorophenone in blood in a fatal poisoning case

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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