Published in:
01-07-2012 | Note
Antiplasmodial decarboxyportentol acetate and 3,4-dehydrotheaspirone from Laumoniera bruceadelpha
Authors:
Hiroshi Morita, Reika Mori, Jun Deguchi, Shiori Oshimi, Yusuke Hirasawa, Wiwied Ekasari, Aty Widyawaruyanti, A. Hamid A. Hadi
Published in:
Journal of Natural Medicines
|
Issue 3/2012
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Abstract
A new spiro heterocycle, decarboxyportentol acetate (1) was isolated from the barks of Laumoniera bruceadelpha Nooteboom (Simaroubaceae), together with 3,4-dehydrotheaspirone (2), and their structures were elucidated by 2D NMR analysis. 3,4-Dehydrotheaspirone (2) showed potent antiplasmodial activity against Plasmodium falciparum 3D7.