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01-04-2010 | Note

Phytochemical analysis of an antiviral fraction of Radix astragali using HPLC–DAD–ESI–MS/MS

Authors: Li Tang, Ying Liu, Yeling Wang, Chunlin Long

Published in: Journal of Natural Medicines | Issue 2/2010

Abstract

Radix astragali (Huangqi in Chinese) is a well-known traditional Chinese medicinal herb that has been used clinically in China for centuries to cure various diseases. To profile the antiviral constituents of this herb, a high-performance liquid chromatography–diode array detector–electrospray ionization–tandem mass spectrometry (HPLC–DAD–ESI–MS/MS) analytical method was developed to separate and determinate the active part of the extract of Radix astragali, which showed potent inhibition of several viruses. By comparing their retention time and MS data with those obtained from the authentic compounds and the published data, a total of 18 compounds, comprising 11 flavonoids and 7 saponins, were identified. This study provides an approach to rapidly characterize bioactive constituents in traditional Chinese medicines (TCMs).

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Title: Phytochemical analysis of an antiviral fraction of Radix astragali using HPLC–DAD–ESI–MS/MS
Authors: Li Tang
Ying Liu
Yeling Wang
Chunlin Long
Publication date: 01-04-2010
Publisher: Springer Japan
Published in: Journal of Natural Medicines / Issue 2/2010
Print ISSN: 1340-3443
Electronic ISSN: 1861-0293
DOI: https://doi.org/10.1007/s11418-009-0381-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Phytochemical analysis of an antiviral fraction of Radix astragali using HPLC–DAD–ESI–MS/MS

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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