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01-04-2006 | Review

Phytochemical and analytical studies of Panax notoginseng (Burk.) F.H. Chen

Authors: Chong-Zhi Wang, Eryn McEntee, Sheila Wicks, Ji-An Wu, Chun-Su Yuan

Published in: Journal of Natural Medicines | Issue 2/2006

Abstract

Panax notoginseng (Burk.) F.H. Chen is distributed throughout the southwest of China, Burma and Nepal. The root of this plant, called notoginseng or sanchi, has a long history of use as a remedy in Oriental traditional medicine. Modern studies have found that extracts and compounds from notoginseng exert various physiological effects. The active constituents are mainly recognized as saponins. In this review, we summarized the discovery and analysis of chemical constituents in notoginseng. Fifty-six saponins from notoginseng were isolated and elucidated. All of them are dammarane saponins, 35 of which can be classified as belonging to the protopanaxadiols group, and 21 as belonging to the protopanaxatriols group. Evidence from phytochemical studies on notoginseng demonstrated that no oleanane-type saponin, which exists in Asian ginseng (Panax ginseng) and American ginseng (Panax quinquefolius), was found. Other types of compounds such as non-protein amino acids, polyacetylenes, phytosterols, flavonoids, and polysaccharides, many of which have pharmacological activities, were also isolated from notoginseng. Analytical studies on notoginseng were carried out based on botanical and phytochemical advances. In the qualitative studies, identification of the herbal materials and extracts was the main objective. The utilization of high-performance liquid chromatography (HPLC) fingerprint and molecular biological methods made the identification accurate and efficient. Spectral, chromatographic and immunoassay methods were used for the quantitative analysis. HPLC methods are the main authority regarding the determination of saponins and other types of constituents. The chromatographic conditions and detectors employed in the HPLC are discussed.

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Zhu Y, Pettolino F, Mau SL, Bacic A (2005) Characterization of cell wall polysaccharides from the medicinal plant Panax notoginseng. Phytochemistry 66:1067–1076CrossRefPubMed

Title: Phytochemical and analytical studies of Panax notoginseng (Burk.) F.H. Chen
Authors: Chong-Zhi Wang
Eryn McEntee
Sheila Wicks
Ji-An Wu
Chun-Su Yuan
Publication date: 01-04-2006
Publisher: Springer-Verlag
Published in: Journal of Natural Medicines / Issue 2/2006
Print ISSN: 1340-3443
Electronic ISSN: 1861-0293
DOI: https://doi.org/10.1007/s11418-005-0027-x

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Phytochemical and analytical studies of Panax notoginseng (Burk.) F.H. Chen

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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