Published in:
01-07-2013
Variation in Use of Buprenorphine and Methadone Treatment by Racial, Ethnic, and Income Characteristics of Residential Social Areas in New York City
Authors:
Helena B. Hansen, MD, PhD, Carole E. Siegel, PhD, Brady G. Case, MD, David N. Bertollo, BA, Danae DiRocco, MPH, Marc Galanter, MD
Published in:
The Journal of Behavioral Health Services & Research
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Issue 3/2013
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Excerpt
Opiate agonist therapies for opiate dependence lower HIV incidence and arrest rates among injection drug users,
1‐
3 thus enhancing access to these treatments is a major public health priority. Buprenorphine, a partial opiate receptor agonist approved by the US FDA in 2002 for treatment of opiate dependence, offers important advantages over methadone maintenance. Buprenorphine is less lethal in overdose than methadone.
4 The most commonly prescribed formulation of buprenorphine, in which it is combined with the opiate antagonist naloxone, produces opiate withdrawal when injected, limiting its abuse potential.
5 Because of these lower risks, buprenorphine can be prescribed by office-based generalist physicians, potentially increasing treatment access and reducing stigma in comparison to methadone,
6 which is restricted to federally regulated methadone clinics. …