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Published in: Sleep and Breathing 2/2014

01-05-2014 | Original Article

Polygraphy vs. polysomnography: missing osas in symptomatic snorers—a reminder for clinicians

Authors: P. Nerfeldt, F. Aoki, D. Friberg

Published in: Sleep and Breathing | Issue 2/2014

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Abstract

Purposes

The purposes of this study are to investigate the usefulness of polygraphy (PG) in diagnosing obstructive sleep apnea (OSA) in sleepy/tired snorers compared to polysomnography (PSG) and, further, to search for suspected respiratory arousals in the PG.

Methods

One hundred eighty-seven adults suffering from sleepiness/tiredness and snoring had undergone ambulant PG and were considered to be normal, using American Academy of Sleep Medicine’s 2007 hypopnea criteria A. After approximately 7 months, in-lab PSG was performed using hypopnea criteria B, where arousals are also recognized. Validated questionnaires (Hospital Anxiety and Depression Scale, self-rated general health) were answered. In a subgroup, the sensitivity and specificity were calculated for flow limitation index (FLI) and flattening index (FlatI) in PG compared with the respiratory distress index (RDI) in PSG.

Results

Despite the normal PG, at PSG, the median RDI was 11.0 (range, 0–89.1). One hundred sixty-eight out of one hundred seventy-eight (90 %) were found to have at least mild OSA and 119/187 (64 %) with moderate–severe OSA according to the RDI values. The sensitivity and specificity were low (<70 %) for FLI and FlatI. Forty-nine percent of the patients rated anxiety at borderline or pathological levels, 35 % rated corresponding depression levels, and 45 % rated poor or fair general health.

Conclusions

PG was insufficient to rule out OSA when the respiratory events were mainly associated with arousals. Almost half of these patients experience low general health and psychiatric problems. We recommend a full-night PSG when PG is “normal”, and patients have symptoms of snoring and sleepiness/tiredness.
Literature
1.
go back to reference Thurnheer R, Bloch KE, Laube I, Gugger M, Heitz M (2007) Respiratory polygraphy in sleep apnoea diagnosis—report of the Swiss respiratory polygraphy registry and systematic review of the literature. Swiss Med Wkly 137:97–102PubMed Thurnheer R, Bloch KE, Laube I, Gugger M, Heitz M (2007) Respiratory polygraphy in sleep apnoea diagnosis—report of the Swiss respiratory polygraphy registry and systematic review of the literature. Swiss Med Wkly 137:97–102PubMed
2.
go back to reference Guilleminault C, Kirisoglu C, Poyares D, Palombini L, Leger D, Farid-Moayer M, Ohayon MM (2006) Upper airway resistance syndrome: a long-term outcome study. J Psychiatr Res 40:273–279PubMedCrossRef Guilleminault C, Kirisoglu C, Poyares D, Palombini L, Leger D, Farid-Moayer M, Ohayon MM (2006) Upper airway resistance syndrome: a long-term outcome study. J Psychiatr Res 40:273–279PubMedCrossRef
3.
go back to reference Jonczak L, Plywaczewski R, Sliwinski P, Bednarek M, Gorecka D, Zielinski J (2009) Evolution of upper airway resistance syndrome. J Sleep Res 18:337–341PubMedCrossRef Jonczak L, Plywaczewski R, Sliwinski P, Bednarek M, Gorecka D, Zielinski J (2009) Evolution of upper airway resistance syndrome. J Sleep Res 18:337–341PubMedCrossRef
4.
go back to reference Friberg D, Ansved T, Borg K, Carlsson-Nordlander B, Larsson H, Svanborg E (1998) Histological indications of a progressive snorers disease in an upper airway muscle. Am J Respir Crit Care Med 157:586–593PubMedCrossRef Friberg D, Ansved T, Borg K, Carlsson-Nordlander B, Larsson H, Svanborg E (1998) Histological indications of a progressive snorers disease in an upper airway muscle. Am J Respir Crit Care Med 157:586–593PubMedCrossRef
5.
go back to reference Iber C, Ancoli-Israel S, Chesson A, Quan S (2007) The AASM manual for the scoring of sleep and associated events : rules, terminology and technical specifications. American Academy of Sleep Medicine, Westchester, IL Iber C, Ancoli-Israel S, Chesson A, Quan S (2007) The AASM manual for the scoring of sleep and associated events : rules, terminology and technical specifications. American Academy of Sleep Medicine, Westchester, IL
6.
go back to reference Berry RB, Budhiraja R, Gottlieb DJ, Gozal D, Iber C, Kapur VK, Marcus CL, Mehra R, Parthasarathy S, Quan SF, Redline S, Strohl KP, Davidson Ward SL, Tangredi MM (2012) Rules for scoring respiratory events in sleep: update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events: deliberations of the sleep apnea definitions task force of the American Academy of Sleep Medicine. J Clin Sleep Med 15:597–619 Berry RB, Budhiraja R, Gottlieb DJ, Gozal D, Iber C, Kapur VK, Marcus CL, Mehra R, Parthasarathy S, Quan SF, Redline S, Strohl KP, Davidson Ward SL, Tangredi MM (2012) Rules for scoring respiratory events in sleep: update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events: deliberations of the sleep apnea definitions task force of the American Academy of Sleep Medicine. J Clin Sleep Med 15:597–619
7.
go back to reference Johns MW (1991) A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep 14:540–545PubMed Johns MW (1991) A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep 14:540–545PubMed
8.
go back to reference Zigmond AS, Sims AC (1983) The effect of the use of the International Classification of Diseases 9th revision: upon hospital in-patient diagnoses. Br J Psychiatry 142:409–413PubMedCrossRef Zigmond AS, Sims AC (1983) The effect of the use of the International Classification of Diseases 9th revision: upon hospital in-patient diagnoses. Br J Psychiatry 142:409–413PubMedCrossRef
9.
go back to reference Idler EL, Russell LB, Davis D (2000) Survival, functional limitations, and self-rated health in the NHANES I Epidemiologic Follow-up Study, 1992. First National Health and Nutrition Examination Survey. Am J Epidemiol 152:874–883PubMedCrossRef Idler EL, Russell LB, Davis D (2000) Survival, functional limitations, and self-rated health in the NHANES I Epidemiologic Follow-up Study, 1992. First National Health and Nutrition Examination Survey. Am J Epidemiol 152:874–883PubMedCrossRef
10.
go back to reference Condos R, Norman RG, Krishnasamy I, Peduzzi N, Goldring RM, Rapoport DM (1994) Flow limitation as a noninvasive assessment of residual upper-airway resistance during continuous positive airway pressure therapy of obstructive sleep apnea. Am J Respir Crit Care Med 150:475–480PubMedCrossRef Condos R, Norman RG, Krishnasamy I, Peduzzi N, Goldring RM, Rapoport DM (1994) Flow limitation as a noninvasive assessment of residual upper-airway resistance during continuous positive airway pressure therapy of obstructive sleep apnea. Am J Respir Crit Care Med 150:475–480PubMedCrossRef
11.
go back to reference Teschler H, Berthon-Jones M, Thompson AB, Henkel A, Henry J, Konietzko N (1996) Automated continuous positive airway pressure titration for obstructive sleep apnea syndrome. Am J Respir Crit Care Med 154:734–740PubMedCrossRef Teschler H, Berthon-Jones M, Thompson AB, Henkel A, Henry J, Konietzko N (1996) Automated continuous positive airway pressure titration for obstructive sleep apnea syndrome. Am J Respir Crit Care Med 154:734–740PubMedCrossRef
12.
go back to reference Ruehland WR, Rochford PD, O’Donoghue FJ, Pierce RJ, Singh P, Thornton AT (2009) The new AASM criteria for scoring hypopneas: impact on the apnea hypopnea index. Sleep 32:150–157PubMedCentralPubMed Ruehland WR, Rochford PD, O’Donoghue FJ, Pierce RJ, Singh P, Thornton AT (2009) The new AASM criteria for scoring hypopneas: impact on the apnea hypopnea index. Sleep 32:150–157PubMedCentralPubMed
13.
go back to reference Parrino L, Ferri R, Zucconi M, Fanfulla F (2009) Commentary from the Italian Association of Sleep Medicine on the AASM manual for the scoring of sleep and associated events: for debate and discussion. Sleep Med 10:799–808PubMedCrossRef Parrino L, Ferri R, Zucconi M, Fanfulla F (2009) Commentary from the Italian Association of Sleep Medicine on the AASM manual for the scoring of sleep and associated events: for debate and discussion. Sleep Med 10:799–808PubMedCrossRef
14.
go back to reference Ravesloot MJ, van Maanen JP, Dun L, de Vries N (2013) The undervalued potential of positional therapy in position-dependent snoring and obstructive sleep apnea—a review of the literature. Sleep Breath 17:39–49PubMedCentralPubMedCrossRef Ravesloot MJ, van Maanen JP, Dun L, de Vries N (2013) The undervalued potential of positional therapy in position-dependent snoring and obstructive sleep apnea—a review of the literature. Sleep Breath 17:39–49PubMedCentralPubMedCrossRef
15.
go back to reference Guilleminault C, Black JE, Palombini L, Ohayon M (2000) A clinical investigation of obstructive sleep apnea syndrome (OSAS) and upper airway resistance syndrome (UARS) patients. Sleep Med 1:51–56PubMedCrossRef Guilleminault C, Black JE, Palombini L, Ohayon M (2000) A clinical investigation of obstructive sleep apnea syndrome (OSAS) and upper airway resistance syndrome (UARS) patients. Sleep Med 1:51–56PubMedCrossRef
16.
go back to reference Stoohs RA, Knaack L, Blum HC, Janicki J, Hohenhorst W (2008) Differences in clinical features of upper airway resistance syndrome, primary snoring, and obstructive sleep apnea/hypopnea syndrome. Sleep Med 9:121–128PubMedCrossRef Stoohs RA, Knaack L, Blum HC, Janicki J, Hohenhorst W (2008) Differences in clinical features of upper airway resistance syndrome, primary snoring, and obstructive sleep apnea/hypopnea syndrome. Sleep Med 9:121–128PubMedCrossRef
17.
go back to reference Young T, Peppard PE, Gottlieb DJ (2002) Epidemiology of obstructive sleep apnea: a population health perspective. Am J Respir Crit Care Med 165:1217–1239PubMedCrossRef Young T, Peppard PE, Gottlieb DJ (2002) Epidemiology of obstructive sleep apnea: a population health perspective. Am J Respir Crit Care Med 165:1217–1239PubMedCrossRef
18.
go back to reference Gabbay IE, Lavie P (2012) Age- and gender-related characteristics of obstructive sleep apnea. Sleep Breath 16:453–460PubMedCrossRef Gabbay IE, Lavie P (2012) Age- and gender-related characteristics of obstructive sleep apnea. Sleep Breath 16:453–460PubMedCrossRef
19.
go back to reference Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S (1993) The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 328:1230–1235PubMedCrossRef Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S (1993) The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 328:1230–1235PubMedCrossRef
20.
go back to reference Marshall NS, Wong KK, Liu PY, Cullen SR, Knuiman MW, Grunstein RR (2008) Sleep apnea as an independent risk factor for all-cause mortality: the Busselton Health Study. Sleep 31:1079–1085PubMedCentralPubMed Marshall NS, Wong KK, Liu PY, Cullen SR, Knuiman MW, Grunstein RR (2008) Sleep apnea as an independent risk factor for all-cause mortality: the Busselton Health Study. Sleep 31:1079–1085PubMedCentralPubMed
21.
go back to reference Young T, Finn L, Peppard PE, Szklo-Coxe M, Austin D, Nieto FJ, Stubbs R, Hla KM (2008) Sleep disordered breathing and mortality: eighteen-year follow-up of the Wisconsin sleep cohort. Sleep 31:1071–1078PubMedCentralPubMed Young T, Finn L, Peppard PE, Szklo-Coxe M, Austin D, Nieto FJ, Stubbs R, Hla KM (2008) Sleep disordered breathing and mortality: eighteen-year follow-up of the Wisconsin sleep cohort. Sleep 31:1071–1078PubMedCentralPubMed
22.
go back to reference Chandra S, Sica AL, Wang J, Lakticova V, Greenberg HE (2013) Respiratory effort-related arousals contribute to sympathetic modulation of heart rate variability. Sleep Breath. doi:10.1007/s11325-013-0823-6 Chandra S, Sica AL, Wang J, Lakticova V, Greenberg HE (2013) Respiratory effort-related arousals contribute to sympathetic modulation of heart rate variability. Sleep Breath. doi:10.​1007/​s11325-013-0823-6
23.
go back to reference Mosko SS, Dickel MJ, Ashurst J (1988) Night-to-night variability in sleep apnea and sleep-related periodic leg movements in the elderly. Sleep 11:340–348PubMed Mosko SS, Dickel MJ, Ashurst J (1988) Night-to-night variability in sleep apnea and sleep-related periodic leg movements in the elderly. Sleep 11:340–348PubMed
24.
go back to reference Chediak AD, Acevedo-Crespo JC, Seiden DJ, Kim HH, Kiel MH (1996) Nightly variability in the indices of sleep-disordered breathing in men being evaluated for impotence with consecutive night polysomnograms. Sleep 19:589–592PubMed Chediak AD, Acevedo-Crespo JC, Seiden DJ, Kim HH, Kiel MH (1996) Nightly variability in the indices of sleep-disordered breathing in men being evaluated for impotence with consecutive night polysomnograms. Sleep 19:589–592PubMed
Metadata
Title
Polygraphy vs. polysomnography: missing osas in symptomatic snorers—a reminder for clinicians
Authors
P. Nerfeldt
F. Aoki
D. Friberg
Publication date
01-05-2014
Publisher
Springer Berlin Heidelberg
Published in
Sleep and Breathing / Issue 2/2014
Print ISSN: 1520-9512
Electronic ISSN: 1522-1709
DOI
https://doi.org/10.1007/s11325-013-0884-6

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