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01-04-2015

Anticoagulation therapy in 2015: where we are and where we are going

Author: Jeffrey I. Weitz

Published in: Journal of Thrombosis and Thrombolysis | Issue 3/2015

Abstract

Oral anticoagulants are a mainstay for the prevention and treatment of venous and arterial thrombosis. In 2015, the non-vitamin K oral anticoagulants (NOACs) are already replacing warfarin for many indications. Ongoing studies are focused on development of antidotes and specific reversal agents for the NOACs, and assessing their utility for prevention of cardiovascular events in patients with heart failure, coronary or peripheral artery disease, or embolic stroke of unknown source. This paper (a) lists the current indications for the NOACs; (b) reviews the current impact of the NOACs in each of these indications; (c) outlines future opportunities for the NOACs, and (e) provides perspective on new anticoagulant strategies that may be safer than the NOACs.

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Title: Anticoagulation therapy in 2015: where we are and where we are going
Author: Jeffrey I. Weitz
Publication date: 01-04-2015
Publisher: Springer US
Published in: Journal of Thrombosis and Thrombolysis / Issue 3/2015
Print ISSN: 0929-5305
Electronic ISSN: 1573-742X
DOI: https://doi.org/10.1007/s11239-015-1194-6

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