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Reviews in Endocrine and Metabolic Disorders
Published in: Reviews in Endocrine and Metabolic Disorders 2/2017

01-06-2017

Low vitamin D status and obesity: Role of nutritionist

Authors: Silvia Savastano, Luigi Barrea, Maria Cristina Savanelli, Francesca Nappi, Carolina Di Somma, Francesco Orio, Annamaria Colao

Published in: Reviews in Endocrine and Metabolic Disorders | Issue 2/2017

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Abstract

Low vitamin D status and obesity have concomitantly reached epidemic levels worldwide. Up to now the direction of the association between low vitamin D status and obesity, the exact mechanisms responsible for this association and the clinical usefulness to increase vitamin D status for reducing adiposity still warrant further evaluation. The aim of the present review was to examine the current evidence linking low vitamin D status and obesity in relation to the role of the nutritionist. On the one side, considering obesity as a causal factor, low sun exposure in obese individuals due to their sedentary lifestyle and less outdoor activity, vitamin D sequestration in adipose tissue, and volumetric dilution of ingested or cutaneously synthesized vitamin D3 in the large fat mass of obese patients, might represent some of the factors playing a major role in the pathogenesis of the low vitamin D status. On the other side, the expression of both vitamin D3 receptors and enzymes responsible for vitamin D3 metabolism in adipocytes depicted a role for the low vitamin D status per se in the development of obesity by modulating adipocyte differentiation and lipid metabolism. Nutritionists need to accurately address the aspects influencing the low vitamin D status in obesity and the vitamin D supplementation in obese individuals.
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Metadata
Title
Low vitamin D status and obesity: Role of nutritionist
Authors
Silvia Savastano
Luigi Barrea
Maria Cristina Savanelli
Francesca Nappi
Carolina Di Somma
Francesco Orio
Annamaria Colao
Publication date
01-06-2017
Publisher
Springer US
Published in
Reviews in Endocrine and Metabolic Disorders / Issue 2/2017
Print ISSN: 1389-9155
Electronic ISSN: 1573-2606
DOI
https://doi.org/10.1007/s11154-017-9410-7

Other articles of this Issue 2/2017

Reviews in Endocrine and Metabolic Disorders 2/2017 Go to the issue

EditorialNotes

New light on an old vitamin: The role of the sunshine vitamin D in chronic disease

EditorialNotes

New light on an old vitamin: The role of the sunshine vitamin D in chronic disease

ReviewPaper

Low serum vitamin D-status, air pollution and obesity: A dangerous liaison

ReviewPaper

Vitamin-D concentrations, cardiovascular risk and events - a review of epidemiological evidence

ReviewPaper

Vitamin D, sub-inflammation and insulin resistance. A window on a potential role for the interaction between bone and glucose metabolism

ReviewPaper

The roles of UVB and vitamin D in reducing risk of cancer incidence and mortality: A review of the epidemiology, clinical trials, and mechanisms
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Obesity Clinical Trial Summary

At a glance: The STEP trials

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A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine
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