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Open Access 01-08-2012 | Review

Self-report fatigue questionnaires in multiple sclerosis, Parkinson’s disease and stroke: a systematic review of measurement properties

Authors: Roy G. Elbers, Marc B. Rietberg, Erwin E. H. van Wegen, John Verhoef, Sharon F. Kramer, Caroline B. Terwee, Gert Kwakkel

Published in: Quality of Life Research | Issue 6/2012

Abstract

Purpose

To critically appraise, compare and summarize the measurement properties of self-report fatigue questionnaires validated in patients with multiple sclerosis (MS), Parkinson’s disease (PD) or stroke.

Methods

MEDLINE, EMBASE, PsycINFO, CINAHL and SPORTdiscus were searched. The COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) checklist was used to assess the methodological quality of studies. A qualitative data synthesis was performed to rate the measurement properties for each questionnaire.

Results

Thirty-eight studies out of 5,336 records met the inclusion criteria, evaluating 31 questionnaires. Moderate evidence was found for adequate internal consistency and structural validity of the Fatigue Scale for Motor and Cognitive functions (FSMC) and for adequate reliability and structural validity of the Unidimensional Fatigue Impact Scale (U-FIS) in MS.

Conclusions

We recommend the FSMC and U-FIS in MS. The Functional Assessment of Chronic Illness Therapy Fatigue subscale (FACIT-F) and Fatigue Severity Scale (FSS) show promise in PD, and the Profile of Mood States Fatigue subscale (POMS-F) for stroke. Future studies should focus on measurement error, responsiveness and interpretability. Studies should also put emphasis on providing input for the theoretical construct of fatigue, allowing the development of questionnaires that reflect generic and disease-specific symptoms of fatigue.

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De Groot, M., Phillips, S., & Eskes, G. (2003). Fatigue associated with stroke and other neurologic conditions: Implications for stroke rehabilitation. Archives of Physical Medicine and Rehabilitation, 84(11), 1714–1720.PubMedCrossRef

Friedman, J., Brown, R., Comella, C., Garber, C., Krupp, L., Lou, J., et al. (2007). Fatigue in Parkinson’s disease: A review. Movement Disorders, 22(3), 297–308.PubMedCrossRef

Debouverie, M., Pittion-Vouyovitch, S., Louis, S., & Guillemin, F. (2007). Validity of a French version of the fatigue impact scale in multiple sclerosis. Multiple Sclerosis, 13(8), 1026–1032.PubMedCrossRef

Lou, J. (2009). Physical and mental fatigue in Parkinson’s disease: epidemiology, pathophysiology and treatment. Drugs and Aging, 26(3), 195–208.PubMedCrossRef

Smets, E., Garssen, B., Bonke, B., & De Haes, J. (1995). The multidimensional fatigue inventory (MFI) psychometric qualities of an instrument to assess fatigue. Journal of Psychosomatic Research, 39(3), 315–325.PubMedCrossRef

Chaudhuri, A., & Behan, P. (2004). Fatigue in neurological disorders. Lancet, 363(9413), 978–988.PubMedCrossRef

Dittner, A., Wessely, S., & Brown, R. (2004). The assessment of fatigue: A practical guide for clinicians and researchers. Journal of Psychosomatic Research, 56(2), 157–170.PubMedCrossRef

Friedman, J., Alves, G., Hagell, P., Marinus, J., Marsh, L., Martínez-Martín, P., et al. (2010). Fatigue rating scales critique and recommendations by the movement disorders society task force on rating scales for Parkinson’s disease. Movement Disorders, 25(7), 805–822.PubMedCrossRef

Hewlett, S., Hehir, M., & Kirwan, J. (2007). Measuring fatigue in rheumatoid arthritis: A systematic review of scales in use. Arthritis and Rheumatism, 57(3), 429–439.PubMedCrossRef

10.

Kos, D., Kerckhofs, E., Ketelaer, P., Duportail, M., Nagels, G., D’hooghe, M., et al. (2004). Self-report assessment of fatigue in multiple sclerosis: A critical evaluation. Occupational Therapy in Health Care, 17(3–4), 45–62.CrossRef

11.

Minton, O., & Stone, P. (2009). A systematic review of the scales used for the measurement of cancer-related fatigue (CRF). Annals of Oncology, 20(1), 17–25.PubMedCrossRef

12.

Mota, D., & Pimenta, C. (2006). Self-report instruments for fatigue assessment: A systematic review. Research and Theory for Nursing Practice, 20(1), 49–78.PubMedCrossRef

13.

Whitehead, L. (2009). The measurement of fatigue in chronic illness: A systematic review of unidimensional and multidimensional fatigue measures. Journal of Pain and Symptom Management, 37(1), 107–128.PubMedCrossRef

14.

Mokkink, L., Terwee, C., Patrick, D., Alonso, J., Stratford, P., Knol, D., et al. (2010). The COSMIN checklist for assessing the methodological quality of studies on measurement properties of health status measurement instruments: An international Delphi study. Quality of Life Research, 19(4), 539–549.PubMedCrossRef

15.

Terwee, C., Jansma, E., Riphagen, I., & de Vet, H. (2009). Development of a methodological PubMed search filter for finding studies on measurement properties of measurement instruments. Quality of Life Research, 18(8), 1115–1123.PubMedCrossRef

16.

Mokkink, L., Terwee, C., Patrick, D., Alonso, J., Stratford, P., Knol, D., et al. (2010). The COSMIN study reached international consensus on taxonomy, terminology, and definitions of measurement properties for health-related patient-reported outcomes. Journal of Clinical Epidemiology, 63(7), 737–745.PubMedCrossRef

17.

Terwee, C., Mokkink, L., Knol, D., Ostelo, R., Bouter, L., & de Vet, H. (2011). Rating the methodological quality in systematic reviews of studies on measurement properties: a scoring system for the COSMIN checklist. Quality of Life Research. doi: 10.1007/s11136-011-9960-1.

18.

Terwee, C., Bot, S., de Boer, M., van der Windt, D., Knol, D., Dekker, J., et al. (2007). Quality criteria were proposed for measurement properties of health status questionnaires. Journal of Clinical Epidemiology, 60(1), 34–42.PubMedCrossRef

19.

Van Tulder, M., Furlan, A., Bombardier, C., & Bouter, L. (2003). Updated method guidelines for systematic reviews in the Cochrane collaboration back review group. Spine, 28(12), 1290–1299.PubMed

20.

Streiner, D., & Norman, G. (2003). Health measurement scales, a practical guide to their development and use. New York: Oxford University Press.

21.

Mokkink, L., Terwee, C., Knol, D., Stratford, P., Alonso, J., Patrick, D., et al. (2010). The COSMIN checklist for evaluating the methodological quality of studies on measurement properties: A clarification of its content. BMC Medical Research Methodology, 10, 22.PubMedCrossRef

22.

Balci, K., Armutlu, K., Fil, A., & Karabudak, R. (2008). If a special scale to measure subjective fatigue in multiple sclerosis was needed? Fizyoterapi Rehabilitasyon, 19(3), 188.

23.

Chang, C., Cella, D., Clarke, S., Heinemann, A., von Roenn, J., & Harvey, R. (2003). Should symptoms be scaled for intensity, frequency, or both? Palliative & Supportive Care, 1(1), 51–60.CrossRef

24.

Chipchase, S., Lincoln, N., & Radford, K. (2003). Measuring fatigue in people with multiple sclerosis. Disability and Rehabilitation, 25(14), 778–784.PubMedCrossRef

25.

Debouverie, M., Pittion-Vouyovitch, S., & Guillemin, F. (2009). Reconsidering fatigue at the onset of multiple sclerosis. Revue Neurologique (Paris), 165(Suppl 4), 135–144.CrossRef

26.

Fisk, J., & Doble, S. (2002). Construction and validation of a fatigue impact scale for daily administration (D-FIS). Quality of Life Research, 11(3), 263–272.PubMedCrossRef

27.

Graham, J., Fisher, N., Granger, C., & Tomita, M. (2007). Test battery for evaluating fatigue in multiple sclerosis patients. International Journal of MS Care, 9(3), 118–125.CrossRef

28.

Gruszczak, A., Bartosik-Psujek, H., Pocinska, K., & Stelmasiak, Z. (2009). Validation analysis of selected psychometric features of Polish version of modified fatigue impact scale—preliminary findings. Neurologia i Neurochirurgia Polska, 43(2), 148–154.PubMed

29.

Haase, V., Lacerda, S., de Paula Lima, E., de Deus Corrêa, T., de Brito, D., & Lana-Peixoto, M. (2004). Assessment of psychosocial functioning in multiple sclerosis: Psychometric characteristics of four self-report measures. Arquivos de Neuro-psiquiatria, 62(2-A), 282–291.PubMed

30.

Iriarte, J., & de Castro, P. (1994). Proposal of a new scale for assessing fatigue in patients with multiple sclerosis. Neurologia, 9(3), 96–100.PubMed

31.

Iriarte, J., Katsamakis, G., & de Castro, P. (1999). The fatigue descriptive scale (FDS): A useful tool to evaluate fatigue in multiple sclerosis. Multiple Sclerosis, 5(1), 10–16.PubMed

32.

Jason, L., Ropacki, M., Santoro, N., Richman, J., Heatherly, W., Taylor, R., et al. (1997). A screening instrument for chronic fatigue syndrome: Reliability and validity. Journal of chronic fatigue syndrome, 3(1), 39–59.CrossRef

33.

Lynch, J., Mead, G., Greig, C., Young, A., Lewis, S., & Sharpe, M. (2007). Fatigue after stroke: The development and evaluation of a case definition. Journal of Psychosomatic Research, 63(5), 539–544.PubMedCrossRef

34.

Montreuil, M. (2000). Analysis of subjective complaints of fatigue in patients with multiple sclerosis. Revue Neurologique (Paris), 156(11), 1048–1050.

35.

Pavan, K., Schmidt, K., Marangoni, B., Fernanda Mendes, M., Tilbery, C., & Lianza, S. (2007). Multiple sclerosis: cross-cultural adaptation and validation of the modified fatigue impact scale. Arquivos de Neuro-psiquiatria, 65(3-A), 669–673.PubMedCrossRef

36.

Taylor, R., Jason, L., & Torres, A. (2000). Fatigue rating scales: An empirical comparison. Psychological Medicine, 30(4), 849–856.PubMedCrossRef

37.

Tseng, B., Gajewski, B., & Kluding, P. (2010). Reliability, responsiveness, and validity of the visual analog fatigue scale to measure exertion fatigue in people with chronic stroke: a preliminary study. Stroke Research and Treatment. doi: 10.4061/2010/412964.

38.

Wu, C., Liu, Z., Zhang, Y., Li, J., & Wang, D. (2008). Validity and reliability of Chinese version of fatigue impact scale in cerebral infarction patients. Neural Regeneration Research, 3(2), 177–181.

39.

Armutlu, K., Korkmaz, N., Keser, I., Sümbüloglu, V., Akbiyik, D., Güney, Z., et al. (2007). The validity and reliability of the fatigue severity scale in Turkish multiple sclerosis patients. International Journal of Rehabilitation Research, 30(1), 81–85.PubMedCrossRef

40.

Armutlu, K., Keser, I., Korkmaz, N., Akbiyik, D., Sümbüloglu, V., Güney, Z., et al. (2007). Psychometric study of Turkish version of fatigue impact scale in multiple sclerosis patients. Journal of the Neurological Sciences, 255(1–2), 64–68.PubMedCrossRef

41.

Benito-León, J., Martínez-Martín, P., Frades, B., Martínez-Ginés, M., de Andrés, C., Meca-Lallana, J., et al. (2007). Impact of fatigue in multiple sclerosis: The fatigue impact scale for daily use (D-FIS). Multiple Sclerosis, 13(5), 645–651.PubMedCrossRef

42.

Brown, R., Dittner, A., Findley, L., & Wessely, S. (2005). The Parkinson fatigue scale. Parkinsonism and Related Disorders, 11(1), 49–55.PubMedCrossRef

43.

Doward, L., Meads, D., Fisk, J., Twiss, J., Hagell, P., Oprandi, N., et al. (2010). International development of the unidimensional fatigue impact scale (U-FIS). Value in Health, 13(4), 463–468.PubMedCrossRef

44.

Fisk, J., Ritvo, P., Ross, L., Haase, D., Marrie, T., & Schlech, W. (1994). Measuring the functional impact of fatigue: Initial validation of the fatigue impact scale. Clinical Infectious Diseases, 18(Suppl 1), 79–83.CrossRef

45.

Flachenecker, P., Kümpfel, T., Kallmann, B., Gottschalk, M., Grauer, O., Rieckmann, P., et al. (2002). Fatigue in multiple sclerosis: A comparison of different rating scales and correlation to clinical parameters. Multiple Sclerosis, 8(6), 523–526.PubMedCrossRef

46.

Flachenecker, P., Müller, G., König, H., Meissner, H., Toyka, K., & Rieckmann, P. (2006). Fatigue in multiple sclerosis: development and validation of the Würzburger fatigue inventory for MS. Der Nervenarzt, 77(2), 165–174.PubMedCrossRef

47.

Flachenecker, P., König, H., Meissner, H., Müller, G., & Rieckmann, P. (2008). Fatigue in multiple sclerosis: Validation of the WEIMUS scale (‘Würzburger erschöpfungs-inventar bei multipler sklerose’). Neurologie & Rehabilitation, 14(6), 299–306.

48.

Flensner, G., Ek, A., & Söderhamn, O. (2005). Reliability and validity of the Swedish version of the fatigue impact scale (FIS). Scandinavian Journal of Occupational Therapy, 12(4), 170–180.PubMedCrossRef

49.

Grace, J., Mendelsohn, A., & Friedman, J. (2007). A comparison of fatigue measures in Parkinson’s disease. Parkinsonism and Related Disorders, 13(7), 443–445.PubMedCrossRef

50.

Hagell, P., Höglund, A., Reimer, J., Erikson, B., Knutsson, I., Widner, H., et al. (2006). Measuring fatigue in Parkinson’s disease: A psychometric study of two brief generic fatigue questionnaires. Journal of Pain and Symptom Management, 32(5), 420–432.PubMedCrossRef

51.

Johansson, S., Ytterberg, C., Back, B., Holmqvist, L., & von Koch, L. (2008). The Swedish occupational fatigue inventory in people with multiple sclerosis. Journal of Rehabilitation Medicine, 40(9), 737–743.PubMed

52.

Kim, E., Lovera, J., Schaben, L., Melara, J., Bourdette, D., & Whitham, R. (2010). Novel method for measurement of fatigue in multiple sclerosis: Real-time digital fatigue score. Journal of Rehabilitation and Development, 47(5), 477–484.CrossRef

53.

Kos, D., Kerckhofs, E., Nagels, G., D’hooghe, M., Duquet, W., Duportail, M., et al. (2003). Assessing fatigue in multiple sclerosis: Dutch modified fatigue impact scale. Acta Neurologica Belgica, 103(4), 185–191.PubMed

54.

Kos, D., Kerckhofs, E., Carrea, I., Verza, R., Ramos, M., & Jansa, J. (2005). Evaluation of the modified fatigue impact scale in four different European countries. Multiple Sclerosis, 11(1), 76–80.PubMedCrossRef

55.

Kos, D., Nagels, G., D’Hooghe, M., Duportail, M., & Kerckhofs, E. (2006). A rapid screening tool for fatigue impact in multiple sclerosis. BMC Neurology, 6, 27.PubMedCrossRef

56.

Krupp, L., LaRocca, G., Muir-Nash, J., & Steinberg, A. (1989). The fatigue severity scale: Application to patients with multiple sclerosis and systemic lupus erythematosus. Archives of Neurology, 46(10), 1121–1123.PubMedCrossRef

57.

Kummer, A., Scalzo, P., Cardoso, F., & Teixeira, A. (2010). Evaluation of fatigue in Parkinson’s disease using the Brazilian version of Parkinson’s fatigue scale. Acta Neurologica Scandinavica. doi: 10.1111/j.1600-0404.2010.01364.x.

58.

Lerdal, A., Johansson, S., Kottorp, A., & von Koch, L. (2010). Psychometric properties of the fatigue severity scale: Rasch analyses of responses in a Norwegian and a Swedish MS cohort. Multiple Sclerosis, 16(6), 733–741.PubMedCrossRef

59.

Losonczi, E., Bencsik, K., Radja, C., Lencsés, G., Török, M., & Vécsei, L. (2010). Validation of the fatigue impact scale in Hungarian patients with multiple sclerosis. Quality of Life Research, 20(2), 301–306.PubMedCrossRef

60.

Marrie, R., Cutter, G., Tyry, T., Hadjimichael, O., Campagnolo, D., & Vollmer, T. (2005). Validation of the NARCOMS registry: Fatigue assessment. Multiple Sclerosis, 11(5), 583–584.PubMedCrossRef

61.

Martínez-Martín, P., Catalan, M., Benito-León, J., Ortega Moreno, A., Zamarbide, I., Cubo, E., et al. (2006). Impact of fatigue in Parkinson’s disease: The fatigue impact scale for daily use (D-FIS). Quality of Life Research, 15(4), 597–606.PubMedCrossRef

62.

Mathiowetz, V. (2003). Test-retest reliability and convergent validity of the fatigue impact scale for persons with multiple sclerosis. The American Journal of Occupational Therapy, 57(4), 389–395.PubMedCrossRef

63.

Mead, G., Lynch, J., Greig, C., Young, A., Lewis, S., & Sharpe, M. (2007). Evaluation of fatigue scales in stroke patients. Stroke, 38(7), 2090–2095.PubMedCrossRef

64.

Meads, D., Doward, L., McKenna, S., Fisk, J., Twiss, J., & Eckert, B. (2009). The development and validation of the unidimensional fatigue impact scale (U-FIS). Multiple Sclerosis, 15(10), 1228–1238.PubMedCrossRef

65.

Mills, R., Young, C., Nicholas, R., Pallant, J., & Tennant, A. (2009). Rash analysis of the fatigue severity scale in multiple sclerosis. Multiple Sclerosis, 15(1), 81–87.PubMedCrossRef

66.

Mills, R., Young, C., Pallant, J., & Tennant, A. (2010). Development of a patient reported outcome scale for fatigue in multiple sclerosis: The neurological fatigue index (NFI-MS). Health and Quality of Life Outcomes, 8, 22.PubMedCrossRef

67.

Mills, R., Young, C., Pallant, J., & Tennant, A. (2010). Rasch analysis of the modified fatigue impact scale (MFIS) in multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry, 81(9), 1049–1051.CrossRef

68.

Penner, I., Raselli, C., Stöcklin, M., Opwis, K., Kappos, L., & Calabrese, P. (2009). The fatigue scale for motor and cognitive functions (FSMC): Validation of a new instrument to assess multiple sclerosis-related fatigue. Multiple Sclerosis, 15(12), 1509–1517.PubMedCrossRef

69.

Rendas-Baum, R., Yang, M., Cattelin, F., Wallenstein, G., & Fisk, J. (2010). A novel approach to estimate the minimally important difference for the fatigue impact scale in multiple sclerosis patients. Quality of Life Research, 19(9), 1349–1358.PubMedCrossRef

70.

Reske, D., Pukrop, R., Scheinig, K., Haupt, W., & Petereit, H. (2006). Measuring fatigue in patients with multiple sclerosis with standardized methods in German-speaking areas. Fortschritte der Neurologie, Psychiatrie, 74(9), 497–502.CrossRef

71.

Rietberg, M., van Wegen, E., & Kwakkel, G. (2010). Measuring fatigue in patients with multiple sclerosis: Reproducibility, responsiveness and concurrent validity of three Dutch self-report questionnaires. Disability and Rehabilitation, 32(22), 1870–1876.PubMedCrossRef

72.

Schwartz, J., Jandorf, L., & Krupp, L. (1993). The measurement of fatigue: A new instrument. Journal of Psychosomatic Research, 37(7), 753–762.PubMedCrossRef

73.

Smith, O., van den Broek, K., Renkens, M., & Denollet, J. (2008). Comparison of fatigue levels in patients with stroke and patients with end-stage heart failure: Application of the fatigue assessment scale. Journal of the American Geriatrics Society, 56(10), 1915–1919.PubMedCrossRef

74.

Twiss, J., Doward, L., McKenna, S., & Eckert, B. (2010). Interpreting scores on multiple sclerosis-specific patient reported outcome measures (the PRIMUS and U-FIS). Health and Quality of Life Outcomes, 8, 117.PubMedCrossRef

75.

Valko, P., Bassetti, C., Bloch, K., Held, U., & Baumann, C. (2008). Validation of the fatigue severity scale in a Swiss cohort. Sleep, 31(11), 1601–1607.PubMed

76.

Kos, D., Kerckhofs, E., Nagels, G., D’hooghe, M., & Ilsbroukx, S. (2008). Origin of fatigue in multiple sclerosis: Review of the literature. Neurorehabilitation and Neural Repair, 22(1), 91–100.PubMedCrossRef

77.

Tseng, B., Billinger, S., Gajewski, B., & Kluding, P. (2010). Exertion fatigue and chronic fatigue are two distinct constructs in people post-stroke. Stroke, 41(12), 2908–2912.PubMedCrossRef

78.

Kwakkel, G. (2009). Towards integrative neurorehabilitation science. Physiotherapy Research International, 14(3), 137–146.PubMedCrossRef

79.

Elbers, R., van Wegen, E., Rochester, L., Hetherington, V., Nieuwboer, A., Willems, A., et al. (2009). Is impact of fatigue an independent factor associated with physical activity in patients with idiopathic Parkinson’s disease? Movement Disorders, 24(10), 1512–1518.PubMedCrossRef

80.

McHorney, C., Ware, J., Lu, J., & Sherbourne, C. (1994). The MOS 36-item short-form health survey (SF-36): III. Tests of data quality, scaling assumptions, and reliability across diverse patient groups. Medical Care, 32(1), 40–60.PubMedCrossRef

81.

Cella, D., Riley, W., Stone, A., Rothrock, N., Reeve, B., Yount, S., et al. (2010). The patient-reported outcomes measurement information system (PROMIS) developed and tested its first wave of adult self-reported health outcome item banks: 2005–2008. Journal of Clinical Epidemiology, 63(11), 1179–1194.PubMedCrossRef

Title: Self-report fatigue questionnaires in multiple sclerosis, Parkinson’s disease and stroke: a systematic review of measurement properties
Authors: Roy G. Elbers
Marc B. Rietberg
Erwin E. H. van Wegen
John Verhoef
Sharon F. Kramer
Caroline B. Terwee
Gert Kwakkel
Publication date: 01-08-2012
Publisher: Springer Netherlands
Published in: Quality of Life Research / Issue 6/2012
Print ISSN: 0962-9343
Electronic ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-011-0009-2

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Self-report fatigue questionnaires in multiple sclerosis, Parkinson’s disease and stroke: a systematic review of measurement properties

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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