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Prevention Science
Published in: Prevention Science 1/2013

01-02-2013

A Systematic Review of Behavioral Interventions to Prevent HIV Infection and Transmission among Heterosexual, Adult Men in Low-and Middle-Income Countries

Authors: Loraine Townsend, Catherine Mathews, Yanga Zembe

Published in: Prevention Science | Issue 1/2013

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Abstract

Prevention of new HIV infections needs to move to the forefront in the fight against HIV and AIDS. In the current economic crisis, low- and middle-income countries (LMICs) should invest limited resources to amass reliable evidence-based information about behavioral prevention efforts, and on behaviors that are driving the epidemic among people who are engaging in those behaviors. This paper aims to provide a systematic review and synthesis of behavioral interventions among a group of people in high HIV-burden countries: heterosexual men in LMICs. The review includes articles published between January 2001 and May 2010 that evaluated behavioral prevention interventions among heterosexual males aged 18+ years in LMICs. The studies were evaluated using the quality assessment tool for quantitative studies developed by the Effective Public Health Practice Project. The review identified 19 articles that met the review's inclusion criteria. Most studies were conducted in South Africa (n=6); two each in Uganda and Thailand; and one in each of Angola, Brazil, Bulgaria, India, Nigeria, the Philippines, Russia, Ukraine and Zimbabwe. Eight of 19 interventions increased condom use among their respective populations. Those interventions that sought to reduce the number of sexual partners had little effect, and those that addressed alcohol consumption and intimate partner violence had mixed effects. There was no evidence for any specific format of intervention that impacted best on any of the targeted risk behaviors. The paucity of evaluated interventions for heterosexual men in LMICs suggests that adult men in these countries remain underrepresented in HIV prevention efforts.
Literature
Baliunas, D., Rehm, J., Irving, H., & Shuper, P. (2010). Alcohol consumption and risk of incident human immunodeficiency virus infection: A meta-analysis. International Journal of Public Health, 55, 159–166.
Bing, E. G., Cheng, K. G., Ortiz, D. J., Ovalle-Bahamón, R. E., Ernesto, F., Weiss, R. E., et al. (2008). Evaluation of a prevention intervention to reduce HIV risk among Angolan soldiers. AIDS and Behavior, 12, 384–395.PubMedCrossRef
Booth, R. E., Lehman, W. E. K., Dvoryak, S., Brewster, J. T., & Sinitsyna, L. (2009). Interventions with injecting drug users in Ukraine. Addiction, 104, 1864–1873.PubMedCrossRef
Cornman, D. H., Schmiege, S. J., Bryan, A., Benziger, T. J., & Fisher, J. D. (2007). An information-motivation-behavioral skills (IMB) model-based HIV prevention intervention for truck drivers in India. Social Science & Medicine, 64, 1572–1584.CrossRef
Cornman, D. H., Kiene, S. M., Christie, S., Fisher, W. A., Shuper, P. A., Pillay, S., et al. (2008). Clinic-based intervention reduces unprotected sexual behavior among HIV-infected patients in KwaZulu-Natal, South Africa: Results of a pilot study. Journal of Acquired Immune Deficiency Syndromes, 48, 553–560.PubMedCrossRef
Crepaz, N., Horn, A. K., Rama, S. M., Griffin, T., Deluca, J. B., Mullins, M. M., et al. (2007). The efficacy of behavioral interventions in reducing HHIV risk sex behaviors and incident sexually transmitted disease in black and Hispanic sexually transmitted disease clinic patients in the United States: A meta-analytic review. Sexually Transmitted Diseases, 34, 319–332.PubMed
Crepaz, N., Lyles, C. M., Wolitski, R. J., Passin, W. F., Rama, S. M., Herbst, J. H., et al. (2006). Do prevention interventions reduce risk behaviours among people living with HIV? A meta-analytic review of controlled trials. AIDS, 20, 143–157.PubMedCrossRef
Darbes, L., Crepaz, N., Lyles, C., Kennedy, G., & Rutherford, G. (2008). The efficacy of behavioral interventions in reducing HIV risk behaviors and incident sexually transmitted diseases in heterosexual African Americans. AIDS, 22, 1177–1194.PubMedCrossRef
Epstein, H. (2008). The invisible cure. Why we are losing the fight against AIDS in Africa. New York: Picador.
Epstein, H. (2010). The mathematics of concurrent partnerships and HIV: A commentary on Lurie and Rosenthal, 2009. AIDS and Behavior, 14, 29–30.PubMedCrossRef
Exner, T. M., Gardos, P. S., Seal, D. W., & Ehrhardt, A. A. (1999). HIV sexual risk reduction interventions with heterosexual men: The forgotten group. AIDS and Behavior, 3, 347–358.CrossRef
Exner, T. M., Mantell, J. E., Adeokun, L. A., Udoh, I. A., Lapido, O. A., Delano, G. E., et al. (2009). Mobilizing men as partners: The results of an intervention to increase dual protection among Nigerian men. Health Education Research, 846–854. doi:10.​1093/​her/​cyp021.
Fisher, J. C., Bang, H., & Kapiga, S. H. (2007). The association between HIV infection and alcohol use: A systematic review and meta-analysis of African studies. Sexually Transmitted Diseases, 34, 856–863.PubMedCrossRef
Foss, A. M., Hossain, M., Vickerman, P. T., & Watts, C. H. (2007). A systematic review of published evidence on intervention impact on condom use in sub-Saharan Africa and Asia. Sexually Transmitted Infections, 83, 510–516.PubMedCrossRef
Green, E. C., Mah, T. L., Ruark, A., & Hearst, N. (2009). A framework of sexual partnerships: Risks and implications for HIV prevention in Africa. Studies in Family Planning, 40, 63–70.
Gregson, S., Adamson, S., Papaya, S., Mundondo, J., Nyamukapa, C. A., Mason, P. R., et al. (2007). Impact and process evaluation of integrated community and clinic-based HIV-1 control: A cluster-randomised trial in Eastern Zimbabwe. PLoS Medicine, 4, 545–555.
Hallett, T. B., Garnett, G. P., Mupamberiyi, Z., & Gregson, S. (2007). Measuring effectiveness in community randomized trials of HIV prevention. International Journal of Epidemiology, 37, 77–87.PubMedCrossRef
Halperin, D., & Epstein, H. (2004). Concurrent sexual partnerships help to explain Africa’s high HIV prevalence: Implications for prevention. The Lancet, 364, 4–6.
Hearst, N., & Chen, S. (2004). Condom promotion for AIDS prevention in the developing world? Is it working? Studies in Family Planning, 35, 39–47.PubMedCrossRef
Herbst, J. H., Kay, L. S., Passin, W. F., Lyles, C. M., Crepaz, N., Marín, B. V., et al. (2007). A systematic review and meta-analysis of behavioral interventions to reduce HIV risk behaviors of Hispanics in the United States and Puerto Rico. AIDS and Behavior, 11, 25–47.PubMedCrossRef
Jewkes, R., Nduna, M., Levin, J., Jama, N., Dunkle, K., Puren, A., et al. (2008). Impact of Stepping Stones on incidence of HIV and HSV-2 and sexual behaviour in rural South Africa: Cluster randomised controlled trial. British Medical Journal, 337, a506. doi:10.​1136/​bmj.​a506.PubMedCrossRef
Jewkes, R., Dunkle, K., Nduna, M., & Shai, N. (2010). Intimate partner violence, relationship power inequity, and incidence of HIV infection in young women in South Africa: A cohort study. The Lancet, 376, 41–48.
Kajubi, P., Kamya, M. R., Kamya, S., Chen, S., McFarland, W., & Hearst, N. (2005). Increasing condom use without reducing HIV risk. Journal of Acquired Immune Deficiency Syndromes, 40, 77–82.PubMedCrossRef
Kalichman, S. C., Simbayi, L. C., Vermaak, R., Cain, D., Jooste, S., & Peltzer, K. (2007a). HIV/AIDS risk reduction counseling for alcohol using sexually transmitted infections clinic patients in Cape Town, South Africa. Journal of Acquired Immune Deficiency Syndromes, 44, 594–600.PubMedCrossRef
Kalichman, S. C., Simbayi, L. C., Kaufman, M., Cain, D., & Jooste, S. (2007b). Alcohol use and sexual risks for HIV/AIDS in sub-Saharan Africa: Systematic review of empirical findings. Prevention Science, 8, 141–151.PubMedCrossRef
Kalichman, S. C., Simbayi, L. C., Vermaak, R., Cain, D., Smith, G., Mthebu, J., et al. (2008). Randomized trial of a community-based alcohol-related HIV risk-reduction intervention for men and women in Cape Town South Africa. Annuls of Behavioral Medicine, 36, 270–279.CrossRef
Kalichman, S. C., Simbayi, L. C., Cloete, A., Clayford, M., Arnolds, W., Mxoli, M., et al. (2009). Integrated gender-based violence and HIV risk reduction intervention for South African men: Results of a quasi-experimental field trial. Prevention Science, 10, 260–269.PubMedCrossRef
Kamali, A., Quigley, M., Nakiyingi, J., Kinsman, J., Kengeya-Kayondo, J., Gopal, R., et al. (2003). Syndromic management of sexually-transmitted infections and behaviour change interventions on transmission of HIV-1 in rural Uganda: A community randomised trial. The Lancet, 361, 645–652.
Kelly, J. A., Amirkhanian, Y. A., Kabakchieva, E., Vassileva, S., McAuliffe, T. L., DiFranceisco, W. J., et al. (2006). Prevention of HIV and sexually transmitted diseases in high risk social networks of young Roma (Gypsy) men in Bulgaria: Randomised controlled trial. British Medical Journal, 333, 1098–1101.
Latkin, C. A., Donnell, D., Metzger, D., Sherman, S., Aramrattna, A., Davis-Vogel, A., et al. (2009). The efficacy of a network intervention to reduce HIV risk behaviors among drug users and risk partners in Chiang Mai, Thailand and Philadelphia, USA. Social Science & Medicine, 68, 740–748.CrossRef
Leclerc-Madlala, S. (2008). Age-disparate and intergenerational sex in southern Africa: Dynamics of hypervulnerability. AIDS, 22, S17–S25.
Lurie, M. N., & Rosenthal, S. (2010). Concurrent partnerships as a driver of the HIV epidemic in sub-Saharan Africa? The evidence is limited. AIDS & Behaviour, 14, 17–24.
Lyles, C. M., Kay, L. S., Crepaz, N., Herbst, J. H., Passin, W. F., Kim, A. S., et al. (2007). Best-evidence interventions: Findings from a systematic review of HIV behavioral interventions for US populations at high risk, 2000–2004. American Journal of Public Health, 97, 133–143.PubMedCrossRef
Mah, T. L., & Halperin, D. T. (2010a). Concurrent sexual partnerships and the HIV epidemics in Africa: Evidence to move forward. AIDS and Behavior, 14, 11–16.PubMedCrossRef
Mah, T., & Halperin, D. T. (2010b). The evidence for the role of concurrent partnerships in Africa’s HIV epidemics: A response to Lurie and Rosenthal. AIDS and Behavior, 14, 25–28.CrossRef
Mah, T., Maughan-Brown, B. (2009). Social and cultural contexts of concurrency in Khayelitsha. Centre for Social Science Research, University of Cape Town Working Paper No. 251.
McCoy, S. I., Kangwende, R. A., & Padian, N. S. (2010). Behavior change interventions to prevent HIV infection among women living in low and middle income countries: A systematic review. AIDS and Behavior, 14, 469–482.PubMedCrossRef
McPhail, C., & Campbell, C. (2001). “I think condoms are good, but, aai, I hate those things”: Condom use among adolescents and young people in a southern African township, South Africa. Social Science & Medicine, 52, 1613–1627.
Merson, M., Padian, N., Coates, T. J., Rao Gupta, G., Bertozzi, S. M., Piot, P., et al. (2008). Combination HIV prevention. The Lancet, 372, 1805–1806.CrossRef
Morisky, D. E., Ang, A., Coly, A., & Tiglao, T. V. (2004). A model HIV/AIDS risk reduction program in the Philippines: A comprehensive community-based approach through participatory action research. Health Promotion International, 19, 69–76.
Morris, M. (2010). Barking up the wrong evidence tree. Commentary on Lurie & Rosenthal, “Concurrent partnerships as a driver of the HIV epidemic in sub-Saharan Africa? The evidence is limited.” AIDS and Behavior, 14, 31–33.PubMedCrossRef
Noguchi, K., Albarracín, D., Durantini, M. R., & Glasman, L. R. (2007). Who participates in which health promotion programs? A meta-analysis of motivations underlying enrollment and retention in HIV-prevention interventions. Psychological Bulletin, 133, 955–975.PubMedCrossRef
Nelson, S. J., Manhart, L. E., Gorbach, P. M., Martin, D. H., Stoner, B. P., Aral, S. O., et al. (2007). Measuring sex partner concurrency: It’s what’s missing that counts. Sexually Transmitted Diseases, 34, 801.807.
Neumann, M. S., Johnson, W. D., Semaan, S., Flores, S. A., Peersman, G., Hedges, L. V., et al. (2002). Review and meta-analysis of HIV prevention intervention research for heterosexual adult populations in the United States. Journal of Acquired Immune Deficiency Syndromes, 30, S106–S117.PubMed
Padian, N. S., McCoy, Sandra, I., Balkus, J. E., & Wasserheit, J. N. (2010). Weighing the gold in the gold standard: Challenges in HIV prevention research. AIDS, 24, 621–635.
Pechansky, F., Bassani, D. G., Von Diemen, L., Kessler, F., Leikefeld, C. G., Surratt, H. L., et al. (2007). Using thought mapping and structured stories to decrease HIV risk behaviors among cocaine injectors and crack smokers in the South of Brazil. Revista Brasileira de Psiquiatria, 29, 233–240.PubMedCrossRef
Richards, J. E., Risser, J. M., Padgett, P. M., Rehma, H. U., Wolverton, M. I., & Arafat, R. R. (2008). Condom use among high-risk heterosexual women with concurrent sexual partners. International Journal of STD & AIDS, 19, 76–771.
Samet, J. H., Krupitsky, E. M., Cheng, D. M., Raj, A., Egorova, V. Y., Levenson, S., et al. (2008). Mitigating risky sexual behaviors among Russian narcology hospital patients: The PREVENT (Partnership to Reduce the Epidemic Via Engagement in Narcology Treatment) randomized controlled trial. Addiction, 103, 1474–1483.
Sherman, S. G., Sutcliffe, C., Srirojn, B., Latkin, C. A., Aramratanna, A., & Celentano, D. D. (2009). Evaluation of a peer network intervention trial among young methamphetamine users in Chiang Mai, Thailand. Social Science & Medicine, 68, 69–79.CrossRef
Shelton, J. D. (2006). Confessions of a condom lover. The Lancet, 368, 1947–1948.CrossRef
Shuper, P. A., Joharchi, N., Irving, H., & Rehm, J. (2009). Alcohol as a correlate of unprotected sexual behavior among people living with HIV/AIDS: Review and meta-analysis. AIDS and Behavior, 13, 1021–1036.PubMedCrossRef
Simbayi, L. C., Kalichman, S. C., Skinner, D., Jooste, S., Cain, D., Cherry, C., et al. (2004). Theory-based HIV risk reduction counseling for sexually transmitted infection clinic patients in Cape Town, South Africa. Sexually Transmitted Diseases, 31, 727–733.PubMedCrossRef
Talbot, M. (1999). Monetary incentives in research and participation in HIV/STD risk reduction programmes. Sexually Transmitted Infections, 75, 1–2.
Townsend, L., Johnson, L. G., Flisher, A. J., Mathews, C., & Zembe, Y. (2010). Effectiveness of respondent-driven sampling to recruit high risk heterosexual men who have multiple female sexual partners: Differences in HIV prevalence and sexual risk behaviours measured at two time points. AIDS and Behavior, 14, 1330–1339.
UNAIDS. (2009a). AIDS epidemic update. Geneva, Switzerland: Joint United Nations Programme on HIV/AIDS.
UNAIDS. (2009b). Impact of the global financial and economic crisis on the AIDS response. Geneva, Switzerland: Joint United Nations Programme on HIV/AIDS.
Ward, D. J., Rowe, B., Pattison, H., Taylor, R. S., & Radcliffe, K. W. (2005). Reducing the risk of sexually transmitted infections in genitourinary medicine clinic patients: A systematic review and meta-analysis of behavioral interventions. Sexually Transmitted Infections, 81, 386–393.
Metadata
Title
A Systematic Review of Behavioral Interventions to Prevent HIV Infection and Transmission among Heterosexual, Adult Men in Low-and Middle-Income Countries
Authors
Loraine Townsend
Catherine Mathews
Yanga Zembe
Publication date
01-02-2013
Publisher
Springer US
Published in
Prevention Science / Issue 1/2013
Print ISSN: 1389-4986
Electronic ISSN: 1573-6695
DOI
https://doi.org/10.1007/s11121-012-0300-7

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