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Published in: Pituitary 1/2017

Open Access 01-02-2017

The genetic background of acromegaly

Authors: Mônica R. Gadelha, Leandro Kasuki, Márta Korbonits

Published in: Pituitary | Issue 1/2017

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Abstract

Acromegaly is caused by a somatotropinoma in the vast majority of the cases. These are monoclonal tumors that can occur sporadically or rarely in a familial setting. In the last few years, novel familial syndromes have been described and recent studies explored the landscape of somatic mutations in sporadic somatotropinomas. This short review concentrates on the current knowledge of the genetic basis of both familial and sporadic acromegaly.
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Metadata
Title
The genetic background of acromegaly
Authors
Mônica R. Gadelha
Leandro Kasuki
Márta Korbonits
Publication date
01-02-2017
Publisher
Springer US
Published in
Pituitary / Issue 1/2017
Print ISSN: 1386-341X
Electronic ISSN: 1573-7403
DOI
https://doi.org/10.1007/s11102-017-0789-7

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