Skip to main content
Top
Published in: Journal of Neuro-Oncology 3/2010

01-09-2010 | Invited Review Free for a limited time

Fractionated radiotherapy for intracranial meningiomas

Authors: Vinai Gondi, Wolfgang A. Tome, Minesh P. Mehta

Published in: Journal of Neuro-Oncology | Issue 3/2010

Login to get access

Abstract

Fractionated external beam radiotherapy (EBRT) has multiple roles in the management of intracranial meningiomas. In multiple series post-operative EBRT has shown improved progression-free survival following subtotal resection and a reduction in long-term failures following an apparent gross total resection. In the definitive setting, the use of EBRT has increased as the growing utilization of neuro-imaging for various conditions identifies skull-based lesions which are not easily resectable. Optic nerve sheath meningiomas represent a classic example of the use of definitive EBRT, given the frequent visual sequelae of surgery or observation. EBRT planning is highly individualized and requires a detailed understanding of tumor grade, adjacent radiosensitive structures such as the anterior optic apparatus, and radiographic characteristics of the tumor such as hyperostosis.
Literature
1.
go back to reference Korshunov A, Shishkina L, Golanov A (2003) Immunohistochemical analysis of p16INK4a, p14ARF, p18INK4c, p21CIP1, p27KIP1 and p73 expression in 271 meningiomas correlation with tumor grade and clinical outcome. Int J Cancer 104:728–734CrossRefPubMed Korshunov A, Shishkina L, Golanov A (2003) Immunohistochemical analysis of p16INK4a, p14ARF, p18INK4c, p21CIP1, p27KIP1 and p73 expression in 271 meningiomas correlation with tumor grade and clinical outcome. Int J Cancer 104:728–734CrossRefPubMed
2.
go back to reference Ho DM, Hsu CY, Ting LT, Chiang H (2002) Histopathology and MIB-1 labeling index predicted recurrence of meningiomas: a proposal of diagnostic criteria for patients with atypical meningioma. Cancer 94:1538–1547CrossRefPubMed Ho DM, Hsu CY, Ting LT, Chiang H (2002) Histopathology and MIB-1 labeling index predicted recurrence of meningiomas: a proposal of diagnostic criteria for patients with atypical meningioma. Cancer 94:1538–1547CrossRefPubMed
3.
go back to reference Perry A, Scheithauer BW, Stafford SL, Lohse CM, Wollan PC (1999) “Malignancy” in meningiomas: a clinicopathologic study of 116 patients, with grading implications. Cancer 85:2046–2056PubMed Perry A, Scheithauer BW, Stafford SL, Lohse CM, Wollan PC (1999) “Malignancy” in meningiomas: a clinicopathologic study of 116 patients, with grading implications. Cancer 85:2046–2056PubMed
4.
go back to reference Perry A, Stafford SL, Scheithauer BW, Suman VJ, Lohse CM (1997) Meningioma grading: an analysis of histologic parameters. Am J Surg Pathol 21:1455–1465CrossRefPubMed Perry A, Stafford SL, Scheithauer BW, Suman VJ, Lohse CM (1997) Meningioma grading: an analysis of histologic parameters. Am J Surg Pathol 21:1455–1465CrossRefPubMed
5.
go back to reference Perry A, Louis DN, Scheithauer BW, Budka H, von Deimling A (2007) Meningeal tumors. In: Louis DN, Ohgaki H, Wiestler OD, Cavenee WK (eds) World health organization classification of tumors of the central nervous system. IARC Press, Lyon, pp 164–172 Perry A, Louis DN, Scheithauer BW, Budka H, von Deimling A (2007) Meningeal tumors. In: Louis DN, Ohgaki H, Wiestler OD, Cavenee WK (eds) World health organization classification of tumors of the central nervous system. IARC Press, Lyon, pp 164–172
6.
go back to reference Louis DN, Scheithauer BW, Budka H (2000) Pathology and genetics of tumors of the nervous system. In: Kleihues P, Cavenee WK (eds) World health organization classification of tumours. IARC Press, Lyon, pp 176–184 Louis DN, Scheithauer BW, Budka H (2000) Pathology and genetics of tumors of the nervous system. In: Kleihues P, Cavenee WK (eds) World health organization classification of tumours. IARC Press, Lyon, pp 176–184
7.
go back to reference Condra KS, Buatti JM, Mendenhall WM, Friedman WA, Marcus RB Jr, Rhoton AL (1997) Benign meningiomas: primary treatment selection affects survival. Int J Radiat Oncol Biol Phys 39:427–436PubMed Condra KS, Buatti JM, Mendenhall WM, Friedman WA, Marcus RB Jr, Rhoton AL (1997) Benign meningiomas: primary treatment selection affects survival. Int J Radiat Oncol Biol Phys 39:427–436PubMed
8.
go back to reference Nutting C, Brada M, Brazil L, Sibtain A, Saran F, Westbury C, Moore A, Thomas DG, Traish D, Ashley S (1999) Radiotherapy in the treatment of benign meningioma of the skull base. J Neurosurg 90:823–827CrossRefPubMed Nutting C, Brada M, Brazil L, Sibtain A, Saran F, Westbury C, Moore A, Thomas DG, Traish D, Ashley S (1999) Radiotherapy in the treatment of benign meningioma of the skull base. J Neurosurg 90:823–827CrossRefPubMed
9.
go back to reference Willis J, Smith C, Ironside JW, Erridge S, Whittle IR, Everington D (2005) The accuracy of meningioma grading: a 10-year retrospective audit. Neuropathol Appl Neurobiol 31:141–149CrossRefPubMed Willis J, Smith C, Ironside JW, Erridge S, Whittle IR, Everington D (2005) The accuracy of meningioma grading: a 10-year retrospective audit. Neuropathol Appl Neurobiol 31:141–149CrossRefPubMed
10.
go back to reference Claus EB, Bondy ML, Schildkraut JM, Wiemels JL, Wrensch M, Black PM (2005) Epidemiology of intracranial meningioma. Neurosurgery 57:1088–1095; discussion 1088–1095CrossRefPubMed Claus EB, Bondy ML, Schildkraut JM, Wiemels JL, Wrensch M, Black PM (2005) Epidemiology of intracranial meningioma. Neurosurgery 57:1088–1095; discussion 1088–1095CrossRefPubMed
11.
go back to reference Perry A (2006) Meningiomas. In: McLendon R, Rosenblum M, Bigner DD (eds) Russel & Rubinsten’s pathology of tumors of the nervous system. Hodder Arnold, London, pp 427–474 Perry A (2006) Meningiomas. In: McLendon R, Rosenblum M, Bigner DD (eds) Russel & Rubinsten’s pathology of tumors of the nervous system. Hodder Arnold, London, pp 427–474
12.
go back to reference Jaaskelainen J, Haltia M, Servo A (1986) Atypical and anaplastic meningiomas: radiology, surgery, radiotherapy, and outcome. Surg Neurol 25:233–242CrossRefPubMed Jaaskelainen J, Haltia M, Servo A (1986) Atypical and anaplastic meningiomas: radiology, surgery, radiotherapy, and outcome. Surg Neurol 25:233–242CrossRefPubMed
13.
go back to reference Perry A (2004) Unmasking the secrets of meningioma: a slow but rewarding journey. Surg Neurol 61:171–173CrossRefPubMed Perry A (2004) Unmasking the secrets of meningioma: a slow but rewarding journey. Surg Neurol 61:171–173CrossRefPubMed
14.
go back to reference Hug EB, Devries A, Thornton AF, Munzenride JE, Pardo FS, Hedley-Whyte ET, Bussiere MR, Ojemann R (2000) Management of atypical and malignant meningiomas: role of high-dose, 3D-conformal radiation therapy. J Neurooncol 48:151–160CrossRefPubMed Hug EB, Devries A, Thornton AF, Munzenride JE, Pardo FS, Hedley-Whyte ET, Bussiere MR, Ojemann R (2000) Management of atypical and malignant meningiomas: role of high-dose, 3D-conformal radiation therapy. J Neurooncol 48:151–160CrossRefPubMed
15.
go back to reference Perry A, Gutmann DH, Reifenberger G (2004) Molecular pathogenesis of meningiomas. J Neurooncol 70:183–202CrossRefPubMed Perry A, Gutmann DH, Reifenberger G (2004) Molecular pathogenesis of meningiomas. J Neurooncol 70:183–202CrossRefPubMed
16.
go back to reference Adegbite AB, Khan MI, Paine KW, Tan LK (1983) The recurrence of intracranial meningiomas after surgical treatment. J Neurosurg 58:51–56CrossRefPubMed Adegbite AB, Khan MI, Paine KW, Tan LK (1983) The recurrence of intracranial meningiomas after surgical treatment. J Neurosurg 58:51–56CrossRefPubMed
17.
go back to reference King DL, Chang CH, Pool JL (1966) Radiotherapy in the management of meningiomas. Acta Radiol Ther Phys Biol 3:26–33PubMed King DL, Chang CH, Pool JL (1966) Radiotherapy in the management of meningiomas. Acta Radiol Ther Phys Biol 3:26–33PubMed
18.
go back to reference Yamashita J, Handa H, Iwaki K, Abe M (1980) Recurrence of intracranial meningiomas, with special reference to radiotherapy. Surg Neurol 14:33–40PubMed Yamashita J, Handa H, Iwaki K, Abe M (1980) Recurrence of intracranial meningiomas, with special reference to radiotherapy. Surg Neurol 14:33–40PubMed
19.
go back to reference Glaholm J, Bloom HJ, Crow JH (1990) The role of radiotherapy in the management of intracranial meningiomas: the Royal Marsden Hospital experience with 186 patients. Int J Radiat Oncol Biol Phys 18:755–761PubMed Glaholm J, Bloom HJ, Crow JH (1990) The role of radiotherapy in the management of intracranial meningiomas: the Royal Marsden Hospital experience with 186 patients. Int J Radiat Oncol Biol Phys 18:755–761PubMed
20.
go back to reference Ron E, Modan B, Boice JD Jr (1988) Mortality after radiotherapy for ringworm of the scalp. Am J Epidemiol 127:713–725PubMed Ron E, Modan B, Boice JD Jr (1988) Mortality after radiotherapy for ringworm of the scalp. Am J Epidemiol 127:713–725PubMed
21.
go back to reference Ron E, Modan B, Boice JD Jr, Alfandary E, Stovall M, Chetrit A, Katz L (1988) Tumors of the brain and nervous system after radiotherapy in childhood. N Engl J Med 319:1033–1039CrossRefPubMed Ron E, Modan B, Boice JD Jr, Alfandary E, Stovall M, Chetrit A, Katz L (1988) Tumors of the brain and nervous system after radiotherapy in childhood. N Engl J Med 319:1033–1039CrossRefPubMed
22.
go back to reference Strojan P, Popovic M, Jereb B (2000) Secondary intracranial meningiomas after high-dose cranial irradiation: report of five cases and review of the literature. Int J Radiat Oncol Biol Phys 48:65–73CrossRefPubMed Strojan P, Popovic M, Jereb B (2000) Secondary intracranial meningiomas after high-dose cranial irradiation: report of five cases and review of the literature. Int J Radiat Oncol Biol Phys 48:65–73CrossRefPubMed
23.
go back to reference Flint-Richter P, Sadetzki S (2007) Genetic predisposition for the development of radiation-associated meningioma: an epidemiological study. Lancet Oncol 8:403–410CrossRefPubMed Flint-Richter P, Sadetzki S (2007) Genetic predisposition for the development of radiation-associated meningioma: an epidemiological study. Lancet Oncol 8:403–410CrossRefPubMed
24.
go back to reference Stafford SL, Perry A, Suman VJ, Meyer FB, Scheithauer BW, Lohse CM, Shaw EG (1998) Primarily resected meningiomas: outcome and prognostic factors in 581 Mayo Clinic patients, 1978 through 1988. Mayo Clin Proc 73:936–942CrossRefPubMed Stafford SL, Perry A, Suman VJ, Meyer FB, Scheithauer BW, Lohse CM, Shaw EG (1998) Primarily resected meningiomas: outcome and prognostic factors in 581 Mayo Clinic patients, 1978 through 1988. Mayo Clin Proc 73:936–942CrossRefPubMed
25.
go back to reference Jung HW, Yoo H, Paek SH, Choi KS (2000) Long-term outcome and growth rate of subtotally resected petroclival meningiomas: experience with 38 cases. Neurosurgery 46:567–574; discussion 574–565CrossRefPubMed Jung HW, Yoo H, Paek SH, Choi KS (2000) Long-term outcome and growth rate of subtotally resected petroclival meningiomas: experience with 38 cases. Neurosurgery 46:567–574; discussion 574–565CrossRefPubMed
26.
go back to reference keyson EW, McCutcheon IE (1996) Management of benign and aggressive intracranial meningiomas. Oncology (Williston Park) 10:747–756; discussion 756–749 keyson EW, McCutcheon IE (1996) Management of benign and aggressive intracranial meningiomas. Oncology (Williston Park) 10:747–756; discussion 756–749
27.
go back to reference Goyal LK, Suh JH, Mohan DS, Prayson RA, Lee J, Barnett GH (2000) Local control and overall survival in atypical meningioma: a retrospective study. Int J Radiat Oncol Biol Phys 46:57–61CrossRefPubMed Goyal LK, Suh JH, Mohan DS, Prayson RA, Lee J, Barnett GH (2000) Local control and overall survival in atypical meningioma: a retrospective study. Int J Radiat Oncol Biol Phys 46:57–61CrossRefPubMed
28.
go back to reference Coke CC, Corn BW, Werner-Wasik M, Xie Y, Curran WJ Jr (1998) Atypical and malignant meningiomas: an outcome report of seventeen cases. J Neurooncol 39:65–70CrossRefPubMed Coke CC, Corn BW, Werner-Wasik M, Xie Y, Curran WJ Jr (1998) Atypical and malignant meningiomas: an outcome report of seventeen cases. J Neurooncol 39:65–70CrossRefPubMed
29.
go back to reference Henzel M, Gross MW, Hamm K, Surber G, Kleinert G, Failing T, Strassmann G, Engenhart-Cabillic R (2006) Stereotactic radiotherapy of meningiomas: symptomatology, acute and late toxicity. Strahlenther Onkol 182:382–388CrossRefPubMed Henzel M, Gross MW, Hamm K, Surber G, Kleinert G, Failing T, Strassmann G, Engenhart-Cabillic R (2006) Stereotactic radiotherapy of meningiomas: symptomatology, acute and late toxicity. Strahlenther Onkol 182:382–388CrossRefPubMed
30.
go back to reference Milker-Zabel S, Zabel A, Schulz-Ertner D, Schlegel W, Wannenmacher M, Debus J (2005) Fractionated stereotactic radiotherapy in patients with benign or atypical intracranial meningioma: long-term experience and prognostic factors. Int J Radiat Oncol Biol Phys 61:809–816PubMed Milker-Zabel S, Zabel A, Schulz-Ertner D, Schlegel W, Wannenmacher M, Debus J (2005) Fractionated stereotactic radiotherapy in patients with benign or atypical intracranial meningioma: long-term experience and prognostic factors. Int J Radiat Oncol Biol Phys 61:809–816PubMed
31.
go back to reference Milker-Zabel S, Zabel-du Bois A, Huber P, Schlegel W, Debus J (2007) Intensity-modulated radiotherapy for complex-shaped meningioma of the skull base: long-term experience of a single institution. Int J Radiat Oncol Biol Phys 68:858–863PubMed Milker-Zabel S, Zabel-du Bois A, Huber P, Schlegel W, Debus J (2007) Intensity-modulated radiotherapy for complex-shaped meningioma of the skull base: long-term experience of a single institution. Int J Radiat Oncol Biol Phys 68:858–863PubMed
32.
go back to reference Debus J, Wuendrich M, Pirzkall A, Hoess A, Schlegel W, Zuna I, Engenhart-Cabillic R, Wannenmacher M (2001) High efficacy of fractionated stereotactic radiotherapy of large base-of-skull meningiomas: long-term results. J Clin Oncol 19:3547–3553PubMed Debus J, Wuendrich M, Pirzkall A, Hoess A, Schlegel W, Zuna I, Engenhart-Cabillic R, Wannenmacher M (2001) High efficacy of fractionated stereotactic radiotherapy of large base-of-skull meningiomas: long-term results. J Clin Oncol 19:3547–3553PubMed
33.
go back to reference Maguire PD, Clough R, Friedman AH, Halperin EC (1999) Fractionated external-beam radiation therapy for meningiomas of the cavernous sinus. Int J Radiat Oncol Biol Phys 44:75–79CrossRefPubMed Maguire PD, Clough R, Friedman AH, Halperin EC (1999) Fractionated external-beam radiation therapy for meningiomas of the cavernous sinus. Int J Radiat Oncol Biol Phys 44:75–79CrossRefPubMed
34.
go back to reference Pirzkall A, Debus J, Haering P, Rhein B, Grosser KH, Hoss A, Wannenmacher M (2003) Intensity modulated radiotherapy (IMRT) for recurrent, residual, or untreated skull-base meningiomas: preliminary clinical experience. Int J Radiat Oncol Biol Phys 55:362–372PubMed Pirzkall A, Debus J, Haering P, Rhein B, Grosser KH, Hoss A, Wannenmacher M (2003) Intensity modulated radiotherapy (IMRT) for recurrent, residual, or untreated skull-base meningiomas: preliminary clinical experience. Int J Radiat Oncol Biol Phys 55:362–372PubMed
35.
go back to reference Turbin RE, Pokorny K (2004) Diagnosis and treatment of orbital optic nerve sheath meningioma. Cancer Control 11:334–341PubMed Turbin RE, Pokorny K (2004) Diagnosis and treatment of orbital optic nerve sheath meningioma. Cancer Control 11:334–341PubMed
36.
go back to reference Smith JL, Vuksanovic MM, Yates BM, Bienfang DC (1981) Radiation therapy for primary optic nerve meningiomas. J Clin Neuroophthalmol 1:85–99PubMed Smith JL, Vuksanovic MM, Yates BM, Bienfang DC (1981) Radiation therapy for primary optic nerve meningiomas. J Clin Neuroophthalmol 1:85–99PubMed
37.
go back to reference Turbin RE, Thompson CR, Kennerdell JS, Cockerham KP, Kupersmith MJ (2002) A long-term visual outcome comparison in patients with optic nerve sheath meningioma managed with observation, surgery, radiotherapy, or surgery and radiotherapy. Ophthalmology 109:890–899; discussion 899–900CrossRefPubMed Turbin RE, Thompson CR, Kennerdell JS, Cockerham KP, Kupersmith MJ (2002) A long-term visual outcome comparison in patients with optic nerve sheath meningioma managed with observation, surgery, radiotherapy, or surgery and radiotherapy. Ophthalmology 109:890–899; discussion 899–900CrossRefPubMed
38.
go back to reference Narayan S, Cornblath WT, Sandler HM, Elner V, Hayman JA (2003) Preliminary visual outcomes after three-dimensional conformal radiation therapy for optic nerve sheath meningioma. Int J Radiat Oncol Biol Phys 56:537–543CrossRefPubMed Narayan S, Cornblath WT, Sandler HM, Elner V, Hayman JA (2003) Preliminary visual outcomes after three-dimensional conformal radiation therapy for optic nerve sheath meningioma. Int J Radiat Oncol Biol Phys 56:537–543CrossRefPubMed
39.
go back to reference Smee RI, Schneider M, Williams JR (2009) Optic nerve sheath meningiomas–non-surgical treatment. Clin Oncol (R Coll Radiol) 21:8–13 Smee RI, Schneider M, Williams JR (2009) Optic nerve sheath meningiomas–non-surgical treatment. Clin Oncol (R Coll Radiol) 21:8–13
40.
go back to reference Baumert BG, Villa S, Studer G, Mirimanoff RO, Davis JB, Landau K, Ducrey N, Arruga J, Lambin P, Pica A (2004) Early improvements in vision after fractionated stereotactic radiotherapy for primary optic nerve sheath meningioma. Radiother Oncol 72:169–174CrossRefPubMed Baumert BG, Villa S, Studer G, Mirimanoff RO, Davis JB, Landau K, Ducrey N, Arruga J, Lambin P, Pica A (2004) Early improvements in vision after fractionated stereotactic radiotherapy for primary optic nerve sheath meningioma. Radiother Oncol 72:169–174CrossRefPubMed
41.
go back to reference Andrews BT, Wilson CB (1988) Suprasellar meningiomas: the effect of tumor location on postoperative visual outcome. J Neurosurg 69:523–528CrossRefPubMed Andrews BT, Wilson CB (1988) Suprasellar meningiomas: the effect of tumor location on postoperative visual outcome. J Neurosurg 69:523–528CrossRefPubMed
42.
go back to reference Liu JK, Forman S, Hershewe GL, Moorthy CR, Benzil DL (2002) Optic nerve sheath meningiomas: visual improvement after stereotactic radiotherapy. Neurosurgery 50:950–955; discussion 955–957CrossRefPubMed Liu JK, Forman S, Hershewe GL, Moorthy CR, Benzil DL (2002) Optic nerve sheath meningiomas: visual improvement after stereotactic radiotherapy. Neurosurgery 50:950–955; discussion 955–957CrossRefPubMed
43.
go back to reference Becker G, Jeremic B, Pitz S, Buchgeister M, Wilhelm H, Schiefer U, Paulsen F, Zrenner E, Bamberg M (2002) Stereotactic fractionated radiotherapy in patients with optic nerve sheath meningioma. Int J Radiat Oncol Biol Phys 54:1422–1429PubMed Becker G, Jeremic B, Pitz S, Buchgeister M, Wilhelm H, Schiefer U, Paulsen F, Zrenner E, Bamberg M (2002) Stereotactic fractionated radiotherapy in patients with optic nerve sheath meningioma. Int J Radiat Oncol Biol Phys 54:1422–1429PubMed
44.
go back to reference Pitz S, Becker G, Schiefer U, Wilhelm H, Jeremic B, Bamberg M, Zrenner E (2002) Stereotactic fractionated irradiation of optic nerve sheath meningioma: a new treatment alternative. Br J Ophthalmol 86:1265–1268CrossRefPubMed Pitz S, Becker G, Schiefer U, Wilhelm H, Jeremic B, Bamberg M, Zrenner E (2002) Stereotactic fractionated irradiation of optic nerve sheath meningioma: a new treatment alternative. Br J Ophthalmol 86:1265–1268CrossRefPubMed
45.
go back to reference Saeed P, Rootman J, Nugent RA, White VA, Mackenzie IR, Koornneef L (2003) Optic nerve sheath meningiomas. Ophthalmology 110:2019–2030CrossRefPubMed Saeed P, Rootman J, Nugent RA, White VA, Mackenzie IR, Koornneef L (2003) Optic nerve sheath meningiomas. Ophthalmology 110:2019–2030CrossRefPubMed
46.
go back to reference Augspurger ME, The BS, Uhl BM, Lee AG, Grant WH, Butler EB, Woo SY (1999) Conformal intensity modulated radiation therapy for the treatment of optic nerve sheath meningioma. Int J Radiat Oncol Biol Phys 45(suppl):324 abstract Augspurger ME, The BS, Uhl BM, Lee AG, Grant WH, Butler EB, Woo SY (1999) Conformal intensity modulated radiation therapy for the treatment of optic nerve sheath meningioma. Int J Radiat Oncol Biol Phys 45(suppl):324 abstract
47.
go back to reference Tsao MN, Hoyt WF, Horton J, Bahary JP, Wara WM, Akazawa C, Larson DA (1999) Improved visual outcome with definitive radiation therapy for optic nerve sheath meningioma. Int J Radiat Oncol Biol Phys 45(3 suppl):324 abstract Tsao MN, Hoyt WF, Horton J, Bahary JP, Wara WM, Akazawa C, Larson DA (1999) Improved visual outcome with definitive radiation therapy for optic nerve sheath meningioma. Int J Radiat Oncol Biol Phys 45(3 suppl):324 abstract
48.
go back to reference Kennerdell JS, Maroon JC, Malton M, Warren FA (1988) The management of optic nerve sheath meningiomas. Am J Ophthalmol 106:450–457PubMed Kennerdell JS, Maroon JC, Malton M, Warren FA (1988) The management of optic nerve sheath meningiomas. Am J Ophthalmol 106:450–457PubMed
49.
go back to reference Kupersmith MJ, Warren FA, Newall J, Ransohoff J (1987) Irradiation of meningiomas of the intracranial anterior visual pathway. Ann Neurol 21:131–137CrossRefPubMed Kupersmith MJ, Warren FA, Newall J, Ransohoff J (1987) Irradiation of meningiomas of the intracranial anterior visual pathway. Ann Neurol 21:131–137CrossRefPubMed
50.
go back to reference Berman D, Miller NR (2006) New concepts in the management of optic nerve sheath meningiomas. Ann Acad Med Singapore 35:168–174PubMed Berman D, Miller NR (2006) New concepts in the management of optic nerve sheath meningiomas. Ann Acad Med Singapore 35:168–174PubMed
51.
go back to reference Pollock BE, Stafford SL, Utter A, Giannini C, Schreiner SA (2003) Stereotactic radiosurgery provides equivalent tumor control to Simpson Grade 1 resection for patients with small- to medium-size meningiomas. Int J Radiat Oncol Biol Phys 55:1000–1005PubMed Pollock BE, Stafford SL, Utter A, Giannini C, Schreiner SA (2003) Stereotactic radiosurgery provides equivalent tumor control to Simpson Grade 1 resection for patients with small- to medium-size meningiomas. Int J Radiat Oncol Biol Phys 55:1000–1005PubMed
52.
go back to reference Kondziolka D, Flickinger JC, Perez B (1998) Judicious resection and/or radiosurgery for parasagittal meningiomas: outcomes from a multicenter review. Gamma Knife Meningioma Study Group. Neurosurgery 43:405–413; discussion 413–404 Kondziolka D, Flickinger JC, Perez B (1998) Judicious resection and/or radiosurgery for parasagittal meningiomas: outcomes from a multicenter review. Gamma Knife Meningioma Study Group. Neurosurgery 43:405–413; discussion 413–404
53.
go back to reference Borovich B, Doron Y (1986) Recurrence of intracranial meningiomas: the role played by regional multicentricity. J Neurosurg 64:58–63CrossRefPubMed Borovich B, Doron Y (1986) Recurrence of intracranial meningiomas: the role played by regional multicentricity. J Neurosurg 64:58–63CrossRefPubMed
54.
go back to reference Nagele T, Petersen D, Klose U, Grodd W, Opitz H, Voigt K (1994) The “dural tail” adjacent to meningiomas studied by dynamic contrast-enhanced MRI: a comparison with histopathology. Neuroradiology 36:303–307CrossRefPubMed Nagele T, Petersen D, Klose U, Grodd W, Opitz H, Voigt K (1994) The “dural tail” adjacent to meningiomas studied by dynamic contrast-enhanced MRI: a comparison with histopathology. Neuroradiology 36:303–307CrossRefPubMed
55.
go back to reference Kawahara Y, Niiro M, Yokoyama S, Kuratsu J (2001) Dural congestion accompanying meningioma invasion into vessels: the dural tail sign. Neuroradiology 43:462–465CrossRefPubMed Kawahara Y, Niiro M, Yokoyama S, Kuratsu J (2001) Dural congestion accompanying meningioma invasion into vessels: the dural tail sign. Neuroradiology 43:462–465CrossRefPubMed
56.
go back to reference Ahmadi J, Hinton DR, Segall HD, Couldwell WT (1994) Surgical implications of magnetic resonance-enhanced dura. Neurosurgery 35:370–377; discussion 377CrossRefPubMed Ahmadi J, Hinton DR, Segall HD, Couldwell WT (1994) Surgical implications of magnetic resonance-enhanced dura. Neurosurgery 35:370–377; discussion 377CrossRefPubMed
57.
go back to reference DiBiase SJ, Kwok Y, Yovino S, Arena C, Naqvi S, Temple R, Regine WF, Amin P, Guo C, Chin LS (2004) Factors predicting local tumor control after gamma knife stereotactic radiosurgery for benign intracranial meningiomas. Int J Radiat Oncol Biol Phys 60:1515–1519PubMed DiBiase SJ, Kwok Y, Yovino S, Arena C, Naqvi S, Temple R, Regine WF, Amin P, Guo C, Chin LS (2004) Factors predicting local tumor control after gamma knife stereotactic radiosurgery for benign intracranial meningiomas. Int J Radiat Oncol Biol Phys 60:1515–1519PubMed
58.
go back to reference Sibtain A, Plowman PN (1999) Stereotactic radiosurgery. VII. Radiosurgery versus conventionally-fractionated radiotherapy in the treatment of cavernous sinus meningiomas. Br J Neurosurg 13:158–166CrossRefPubMed Sibtain A, Plowman PN (1999) Stereotactic radiosurgery. VII. Radiosurgery versus conventionally-fractionated radiotherapy in the treatment of cavernous sinus meningiomas. Br J Neurosurg 13:158–166CrossRefPubMed
59.
go back to reference Goldsmith B (1998) Meningioma. In: Leibel SA, Phillips TS (eds) Textbook of radiation oncology. WB Saunders, Philadelphia, pp 324–340 Goldsmith B (1998) Meningioma. In: Leibel SA, Phillips TS (eds) Textbook of radiation oncology. WB Saunders, Philadelphia, pp 324–340
60.
go back to reference Simpson D (1957) Graded resection extent based upon clinically apparent recurrence of intracranial meningioma in 265 patients from Radcliffe Infirmary in Oxford as well as patients from Dr. Hugh Cairns in London. J Neurol Neurosurg Psychiat 20:22–39CrossRefPubMed Simpson D (1957) Graded resection extent based upon clinically apparent recurrence of intracranial meningioma in 265 patients from Radcliffe Infirmary in Oxford as well as patients from Dr. Hugh Cairns in London. J Neurol Neurosurg Psychiat 20:22–39CrossRefPubMed
61.
go back to reference Goldsmith BJ, Wara WM, Wilson CB, Larson DA (1994) Postoperative irradiation for subtotally resected meningiomas. A retrospective analysis of 140 patients treated from 1967 to 1990. J Neurosurg 80:195–201CrossRefPubMed Goldsmith BJ, Wara WM, Wilson CB, Larson DA (1994) Postoperative irradiation for subtotally resected meningiomas. A retrospective analysis of 140 patients treated from 1967 to 1990. J Neurosurg 80:195–201CrossRefPubMed
62.
go back to reference Milosevic MF, Frost PJ, Laperriere NJ, Wong CS, Simpson WJ (1996) Radiotherapy for atypical or malignant intracranial meningioma. Int J Radiat Oncol Biol Phys 34:817–822PubMed Milosevic MF, Frost PJ, Laperriere NJ, Wong CS, Simpson WJ (1996) Radiotherapy for atypical or malignant intracranial meningioma. Int J Radiat Oncol Biol Phys 34:817–822PubMed
63.
go back to reference Barbaro NM, Gutin PH, Wilson CB, Sheline GE, Boldrey EB, Wara WM (1987) Radiation therapy in the treatment of partially resected meningiomas. Neurosurgery 20:525–528CrossRefPubMed Barbaro NM, Gutin PH, Wilson CB, Sheline GE, Boldrey EB, Wara WM (1987) Radiation therapy in the treatment of partially resected meningiomas. Neurosurgery 20:525–528CrossRefPubMed
64.
go back to reference Taylor BW Jr, Marcus RB Jr, Friedman WA, Ballinger WE Jr, Million RR (1988) The meningioma controversy: postoperative radiation therapy. Int J Radiat Oncol Biol Phys 15:299–304PubMed Taylor BW Jr, Marcus RB Jr, Friedman WA, Ballinger WE Jr, Million RR (1988) The meningioma controversy: postoperative radiation therapy. Int J Radiat Oncol Biol Phys 15:299–304PubMed
65.
go back to reference Goldsmith BJ, Rosenthal SA, Wara WM, Larson DA (1992) Optic neuropathy after irradiation of meningioma. Radiology 185:71–76PubMed Goldsmith BJ, Rosenthal SA, Wara WM, Larson DA (1992) Optic neuropathy after irradiation of meningioma. Radiology 185:71–76PubMed
66.
go back to reference Shrieve DC, Hazard L, Boucher K, Jensen RL (2004) Dose fractionation in stereotactic radiotherapy for parasellar meningiomas: radiobiological considerations of efficacy and optic nerve tolerance. J Neurosurg 101(Suppl 3):390–395PubMed Shrieve DC, Hazard L, Boucher K, Jensen RL (2004) Dose fractionation in stereotactic radiotherapy for parasellar meningiomas: radiobiological considerations of efficacy and optic nerve tolerance. J Neurosurg 101(Suppl 3):390–395PubMed
67.
go back to reference Miralbell R, Linggood RM, de la Monte S, Convery K, Munzenrider JE, Mirimanoff RO (1992) The role of radiotherapy in the treatment of subtotally resected benign meningiomas. J Neurooncol 13:157–164CrossRefPubMed Miralbell R, Linggood RM, de la Monte S, Convery K, Munzenrider JE, Mirimanoff RO (1992) The role of radiotherapy in the treatment of subtotally resected benign meningiomas. J Neurooncol 13:157–164CrossRefPubMed
68.
go back to reference Uy NW, Woo SY, Teh BS, Mai WY, Carpenter LS, Chiu JK, Lu HH, Gildenberg P, Trask T, Grant WH, Butler EB (2002) Intensity-modulated radiation therapy (IMRT) for meningioma. Int J Radiat Oncol Biol Phys 53:1265–1270CrossRefPubMed Uy NW, Woo SY, Teh BS, Mai WY, Carpenter LS, Chiu JK, Lu HH, Gildenberg P, Trask T, Grant WH, Butler EB (2002) Intensity-modulated radiation therapy (IMRT) for meningioma. Int J Radiat Oncol Biol Phys 53:1265–1270CrossRefPubMed
69.
go back to reference al-Mefty O, Kersh JE, Routh A, Smith RR (1990) The long-term side effects of radiation therapy for benign brain tumors in adults. J Neurosurg 73:502–512CrossRefPubMed al-Mefty O, Kersh JE, Routh A, Smith RR (1990) The long-term side effects of radiation therapy for benign brain tumors in adults. J Neurosurg 73:502–512CrossRefPubMed
70.
go back to reference Paek SH, Kim CY, Kim YY, Park IA, Kim MS, Kim DG, Jung HW (2002) Correlation of clinical and biological parameters with peritumoral edema in meningioma. J Neurooncol 60:235–245CrossRefPubMed Paek SH, Kim CY, Kim YY, Park IA, Kim MS, Kim DG, Jung HW (2002) Correlation of clinical and biological parameters with peritumoral edema in meningioma. J Neurooncol 60:235–245CrossRefPubMed
71.
go back to reference Steinvorth S, Welzel G, Fuss M, Debus J, Wildermuth S, Wannenmacher M, Wenz F (2003) Neuropsychological outcome after fractionated stereotactic radiotherapy (FSRT) for base of skull meningiomas: a prospective 1-year follow-up. Radiother Oncol 69:177–182CrossRefPubMed Steinvorth S, Welzel G, Fuss M, Debus J, Wildermuth S, Wannenmacher M, Wenz F (2003) Neuropsychological outcome after fractionated stereotactic radiotherapy (FSRT) for base of skull meningiomas: a prospective 1-year follow-up. Radiother Oncol 69:177–182CrossRefPubMed
72.
go back to reference Mirimanoff RO, Dosoretz DE, Linggood RM, Ojemann RG, Martuza RL (1985) Meningioma: analysis of recurrence and progression following neurosurgical resection. J Neurosurg 62:18–24CrossRefPubMed Mirimanoff RO, Dosoretz DE, Linggood RM, Ojemann RG, Martuza RL (1985) Meningioma: analysis of recurrence and progression following neurosurgical resection. J Neurosurg 62:18–24CrossRefPubMed
73.
go back to reference Mahmood A, Qureshi NH, Malik GM (1994) Intracranial meningiomas: analysis of recurrence after surgical treatment. Acta Neurochir (Wien) 126:53–58CrossRef Mahmood A, Qureshi NH, Malik GM (1994) Intracranial meningiomas: analysis of recurrence after surgical treatment. Acta Neurochir (Wien) 126:53–58CrossRef
74.
go back to reference Peele KA, Kennerdell JS, Maroon JC, Kalnicki S, Kazim M, Gardner T, Malton M, Goodglick T, Rosen C (1996) The role of postoperative irradiation in the management of sphenoid wing meningiomas. A preliminary report. Ophthalmology 103:1761–1766; discussion 1766–1767PubMed Peele KA, Kennerdell JS, Maroon JC, Kalnicki S, Kazim M, Gardner T, Malton M, Goodglick T, Rosen C (1996) The role of postoperative irradiation in the management of sphenoid wing meningiomas. A preliminary report. Ophthalmology 103:1761–1766; discussion 1766–1767PubMed
75.
go back to reference Vendrely V, Maire JP, Darrouzet V, Bonichon N, San Galli F, Celerier D, Causse N, Demeaux H, Trouette R, Dahan O, Recaldini L, Guerin J, Caudry M (1999) Fractionated radiotherapy of intracranial meningiomas: 15 years’ experience at the Bordeaux University Hospital Center. Cancer Radiother 3:311–317PubMed Vendrely V, Maire JP, Darrouzet V, Bonichon N, San Galli F, Celerier D, Causse N, Demeaux H, Trouette R, Dahan O, Recaldini L, Guerin J, Caudry M (1999) Fractionated radiotherapy of intracranial meningiomas: 15 years’ experience at the Bordeaux University Hospital Center. Cancer Radiother 3:311–317PubMed
76.
go back to reference Wenkel E, Thornton AF, Finkelstein D, Adams J, Lyons S, De La Monte S, Ojeman RG, Munzenrider JE (2000) Benign meningioma: partially resected, biopsied, and recurrent intracranial tumors treated with combined proton and photon radiotherapy. Int J Radiat Oncol Biol Phys 48:1363–1370PubMed Wenkel E, Thornton AF, Finkelstein D, Adams J, Lyons S, De La Monte S, Ojeman RG, Munzenrider JE (2000) Benign meningioma: partially resected, biopsied, and recurrent intracranial tumors treated with combined proton and photon radiotherapy. Int J Radiat Oncol Biol Phys 48:1363–1370PubMed
77.
go back to reference Pourel N, Auque J, Bracard S, Hoffstetter S, Luporsi E, Vignaud JM, Bey P (2001) Efficacy of external fractionated radiation therapy in the treatment of meningiomas: a 20-year experience. Radiother Oncol 61:65–70CrossRefPubMed Pourel N, Auque J, Bracard S, Hoffstetter S, Luporsi E, Vignaud JM, Bey P (2001) Efficacy of external fractionated radiation therapy in the treatment of meningiomas: a 20-year experience. Radiother Oncol 61:65–70CrossRefPubMed
78.
go back to reference Dufour H, Muracciole X, Metellus P, Regis J, Chinot O, Grisoli F (2001) Long-term tumor control and functional outcome in patients with cavernous sinus meningiomas treated by radiotherapy with or without previous surgery: is there an alternative to aggressive tumor removal? Neurosurgery 48:285–294; discussion 294–286CrossRefPubMed Dufour H, Muracciole X, Metellus P, Regis J, Chinot O, Grisoli F (2001) Long-term tumor control and functional outcome in patients with cavernous sinus meningiomas treated by radiotherapy with or without previous surgery: is there an alternative to aggressive tumor removal? Neurosurgery 48:285–294; discussion 294–286CrossRefPubMed
79.
go back to reference Jalali R, Loughrey C, Baumert B, Perks J, Warrington AP, Traish D, Ashley S, Brada M (2002) High precision focused irradiation in the form of fractionated stereotactic conformal radiotherapy (SCRT) for benign meningiomas predominantly in the skull base location. Clin Oncol (R Coll Radiol) 14:103–109 Jalali R, Loughrey C, Baumert B, Perks J, Warrington AP, Traish D, Ashley S, Brada M (2002) High precision focused irradiation in the form of fractionated stereotactic conformal radiotherapy (SCRT) for benign meningiomas predominantly in the skull base location. Clin Oncol (R Coll Radiol) 14:103–109
80.
go back to reference Soyuer S, Chang EL, Selek U, Shi W, Maor MH, DeMonte F (2004) Radiotherapy after surgery for benign cerebral meningioma. Radiother Oncol 71:85–90CrossRefPubMed Soyuer S, Chang EL, Selek U, Shi W, Maor MH, DeMonte F (2004) Radiotherapy after surgery for benign cerebral meningioma. Radiother Oncol 71:85–90CrossRefPubMed
81.
go back to reference Selch MT, Ahn E, Laskari A, Lee SP, Agazaryan N, Solberg TD, Cabatan-Awang C, Frighetto L, Desalles AA (2004) Stereotactic radiotherapy for treatment of cavernous sinus meningiomas. Int J Radiat Oncol Biol Phys 59:101–111PubMed Selch MT, Ahn E, Laskari A, Lee SP, Agazaryan N, Solberg TD, Cabatan-Awang C, Frighetto L, Desalles AA (2004) Stereotactic radiotherapy for treatment of cavernous sinus meningiomas. Int J Radiat Oncol Biol Phys 59:101–111PubMed
Metadata
Title
Fractionated radiotherapy for intracranial meningiomas
Authors
Vinai Gondi
Wolfgang A. Tome
Minesh P. Mehta
Publication date
01-09-2010
Publisher
Springer US
Published in
Journal of Neuro-Oncology / Issue 3/2010
Print ISSN: 0167-594X
Electronic ISSN: 1573-7373
DOI
https://doi.org/10.1007/s11060-010-0368-5

Other articles of this Issue 3/2010

Journal of Neuro-Oncology 3/2010 Go to the issue