Published in:
01-11-2009 | Case Report
Neurolymphomatosis: a rare metastatic complication of diffuse large B-Cell lymphoma
Authors:
Marc C. Chamberlain, James Fink
Published in:
Journal of Neuro-Oncology
|
Issue 2/2009
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Abstract
To report the occurrence of neurolymphomatosis in a patient with previously treated systemic diffuse B-cell lymphoma (DLBCL). A case report. University medical center. A 54-year old woman with previously treated DLBCL developed sequential mono-, di- and triparesis 3-months after completion of systemic therapy. MR of lumbar and brachial plexus revealed diffuse involvement of nerve roots and plexus. High-dose methotrexate and involved-field radiotherapy. Neurolymphomatosis, although rare, is increasingly recognized with peripheral and central nervous system MRI. Treatment remains unsatisfactory as treatment with methotrexate-based chemotherapy and irradiation is only partially effective.