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Published in: Journal of Neuro-Oncology 2/2007

01-06-2007 | Clinical–Patient Studies

Choroid plexus Acinar adenoma: a case report

Authors: Daniel Rembao-Bojórquez, Rosalba Vega, Luis Bermúdez-Maldonado, Ramón Gutiérrez, Citlaltepetl Salinas, Martha Tena-Suck

Published in: Journal of Neuro-Oncology | Issue 2/2007

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Abstract

Mucus-secreting adenomas or acinar adenoma of the choroid plexus are very rare. We report the case of a 79-year-old male with a 3-year history of occipital headaches with vomiting, ataxia and cerebellar signs. He was first seen due to difficulty while walking. He was admitted to the hospital with significant tumor expansion and clinical deterioration. CT and MRI revealed obstructive hydrocephalus secondary to a large fourth ventricular cyst mass, which enhanced markedly on contrast administration. Pathological findings were consistent with an acinar choroid plexus adenoma. The tumor was attached to the ependymal lining and was strongly adhered to the walls and floor of the IV ventricle. Post-operative bleeding complicated partial removal of this tumor. The patient died 6 h after surgery.
Literature
1.
go back to reference Aguzzi A, Brandner S, Paulus W (2000) Choroid plexus tumors. In: Kleihues P, Cavenee WK (eds) World Health Organization classification of tumours, tumours of the nervous system. IARC, Lyons, pp 84–86 Aguzzi A, Brandner S, Paulus W (2000) Choroid plexus tumors. In: Kleihues P, Cavenee WK (eds) World Health Organization classification of tumours, tumours of the nervous system. IARC, Lyons, pp 84–86
2.
go back to reference Davis RL, Fox GE (1970) Acinar choroid plexus adenoma. Case report. J Neurosurg 33:587–590 Davis RL, Fox GE (1970) Acinar choroid plexus adenoma. Case report. J Neurosurg 33:587–590
3.
go back to reference Andreini L, Doglioni C, Giangaspero F (1991) Tubular adenoma of choroid plexus: a case report. Clin Neuropathol 10:137–140PubMed Andreini L, Doglioni C, Giangaspero F (1991) Tubular adenoma of choroid plexus: a case report. Clin Neuropathol 10:137–140PubMed
4.
go back to reference Aquilina K, Nanra JS, Allcutt DA, Farrell M (2005) Choroid plexus adenoma: case report and review of the literature. Childs Nerv Syst 21:410–415PubMedCrossRef Aquilina K, Nanra JS, Allcutt DA, Farrell M (2005) Choroid plexus adenoma: case report and review of the literature. Childs Nerv Syst 21:410–415PubMedCrossRef
5.
go back to reference Eljamel MS, Jeffreys RV (1990) Mucous-secreting choroid plexus adenoma–case report and review of the literature. Neuropediatrics 21:55–56PubMedCrossRef Eljamel MS, Jeffreys RV (1990) Mucous-secreting choroid plexus adenoma–case report and review of the literature. Neuropediatrics 21:55–56PubMedCrossRef
6.
go back to reference Shintaku M (2002) Tubular (acinar) transformation of the choroid plexus epithelium. Brain Tumor Pathol 19:31–34PubMedCrossRef Shintaku M (2002) Tubular (acinar) transformation of the choroid plexus epithelium. Brain Tumor Pathol 19:31–34PubMedCrossRef
7.
go back to reference Varga Z, Vajtai I (1999) Surgical removal of a choroid plexus adenoma using the argon beam coagulator: technical case report. Neurosurgery 44:427–428PubMedCrossRef Varga Z, Vajtai I (1999) Surgical removal of a choroid plexus adenoma using the argon beam coagulator: technical case report. Neurosurgery 44:427–428PubMedCrossRef
8.
go back to reference Sutton LN, Golden JA, Needle M, Bonner K, Benetez R (1998) Surgical removal of a choroid plexus adenoma using the argon beam coagulator: technical case report. Neurosurgery 43:171–173PubMedCrossRef Sutton LN, Golden JA, Needle M, Bonner K, Benetez R (1998) Surgical removal of a choroid plexus adenoma using the argon beam coagulator: technical case report. Neurosurgery 43:171–173PubMedCrossRef
9.
go back to reference Varga Z, Vajtai I, Marino S, Schauble B, Yonekawa Y, Aguzzi A (1996) Tubular adenoma of the choroid plexus: evidence for glandular differentiation of the neuroepithelium. Pathol Res Pract 192:840–844PubMed Varga Z, Vajtai I, Marino S, Schauble B, Yonekawa Y, Aguzzi A (1996) Tubular adenoma of the choroid plexus: evidence for glandular differentiation of the neuroepithelium. Pathol Res Pract 192:840–844PubMed
10.
go back to reference Duckett S, Osterholm J, Schaefer D, Gonzales C, Schwartzman RJ (1991) Ossified mucin-secreting choroid plexus adenoma: case report. Neurosurgery 29:130–132PubMedCrossRef Duckett S, Osterholm J, Schaefer D, Gonzales C, Schwartzman RJ (1991) Ossified mucin-secreting choroid plexus adenoma: case report. Neurosurgery 29:130–132PubMedCrossRef
11.
go back to reference Ajir F, Chanbusarakum K, Bolles JC (1982) Acinar choroid plexus adenoma of the fourth ventricle. Surg Neurol 17:290–292PubMedCrossRef Ajir F, Chanbusarakum K, Bolles JC (1982) Acinar choroid plexus adenoma of the fourth ventricle. Surg Neurol 17:290–292PubMedCrossRef
12.
go back to reference Koeller KK, Sandberg GD (2002) Armed Forces Institute of Pathology. From the archives of the AFIP. Cerebral intraventricular neoplasms: radiological–pathologic correlation. Radiographics 22:1473–1505PubMedCrossRef Koeller KK, Sandberg GD (2002) Armed Forces Institute of Pathology. From the archives of the AFIP. Cerebral intraventricular neoplasms: radiological–pathologic correlation. Radiographics 22:1473–1505PubMedCrossRef
13.
go back to reference Krishnan S, Brown PD, Scheithauer BW, Ebersold MJ, Hammack JE, Buckner JC (2004) Choroid plexus papillomas: a single institutional experience. J Neurooncol 68:49–55PubMedCrossRef Krishnan S, Brown PD, Scheithauer BW, Ebersold MJ, Hammack JE, Buckner JC (2004) Choroid plexus papillomas: a single institutional experience. J Neurooncol 68:49–55PubMedCrossRef
14.
go back to reference Nelson MD Jr, Maher K, Gilles FH (2004) A different approach to cysts of the posterior fossa. Pediatr Radiol 34:720–732PubMedCrossRef Nelson MD Jr, Maher K, Gilles FH (2004) A different approach to cysts of the posterior fossa. Pediatr Radiol 34:720–732PubMedCrossRef
15.
go back to reference Shuangshoti S (1980) Melanotic mucin-producing neuroepithelial neoplasm of mesencephalon with consideration of similar tumours in different locations. J Neurol Neurosurg Psychiatry 43:810–817PubMed Shuangshoti S (1980) Melanotic mucin-producing neuroepithelial neoplasm of mesencephalon with consideration of similar tumours in different locations. J Neurol Neurosurg Psychiatry 43:810–817PubMed
16.
go back to reference Russell DS, Rubenstein LJ (1989) Pathology of tumours of the nervous system. Williams & Wilkins, Baltimore, p 391 Russell DS, Rubenstein LJ (1989) Pathology of tumours of the nervous system. Williams & Wilkins, Baltimore, p 391
17.
go back to reference Corcoran GM, Frazier SR, Prayson RA (2001) Choroid plexus papilloma with osseous and adipose metaplasia. Ann Diagn Pathol 5:43–47PubMedCrossRef Corcoran GM, Frazier SR, Prayson RA (2001) Choroid plexus papilloma with osseous and adipose metaplasia. Ann Diagn Pathol 5:43–47PubMedCrossRef
18.
go back to reference Watanabe K, Ando Y, Iwanaga H, Ochiai C, Nagai M, Okada K, Watanabe N (1995) Choroid plexus papilloma containing melanin pigment. Clin Neuropathol 14:159–161, 415PubMed Watanabe K, Ando Y, Iwanaga H, Ochiai C, Nagai M, Okada K, Watanabe N (1995) Choroid plexus papilloma containing melanin pigment. Clin Neuropathol 14:159–161, 415PubMed
19.
go back to reference Patanakar T, Prasad S, Mukherji SK, Armao D (2000) Cystic variant of choroid plexus papilloma. Clin Imaging 24:130–131PubMedCrossRef Patanakar T, Prasad S, Mukherji SK, Armao D (2000) Cystic variant of choroid plexus papilloma. Clin Imaging 24:130–131PubMedCrossRef
20.
go back to reference Cenacchi G, Morra I, Forni M, Giangaspero F (1999) Mucin-secreting cellular ependymoma: a light and electron microscopy study. Ultrastruct Pathol 23:319–323PubMedCrossRef Cenacchi G, Morra I, Forni M, Giangaspero F (1999) Mucin-secreting cellular ependymoma: a light and electron microscopy study. Ultrastruct Pathol 23:319–323PubMedCrossRef
21.
go back to reference Cohen ZR, Suki D, Weinberg JS, Marmor E, Lang FF, Gershenson DM, Sawaya R (2004) Brain metastases in patients with ovarian carcinoma: prognostic factors and outcome. J Neurooncol 66:313–325PubMedCrossRef Cohen ZR, Suki D, Weinberg JS, Marmor E, Lang FF, Gershenson DM, Sawaya R (2004) Brain metastases in patients with ovarian carcinoma: prognostic factors and outcome. J Neurooncol 66:313–325PubMedCrossRef
22.
go back to reference Garg PK, Bohidar NP, Sharma MP, Mohapatra AK, Saha A, Pande GK (1999) Isolated cerebellar metastasis from carcinoma of the colon. Postgrad Med J 75:119–120PubMed Garg PK, Bohidar NP, Sharma MP, Mohapatra AK, Saha A, Pande GK (1999) Isolated cerebellar metastasis from carcinoma of the colon. Postgrad Med J 75:119–120PubMed
23.
go back to reference Emerson RE, Azzarelli B (2004) Enterogenous cysts of the spinal canal and cerebellopontine angle. Appl Immunohistochem Mol Morphol 12:230–233PubMed Emerson RE, Azzarelli B (2004) Enterogenous cysts of the spinal canal and cerebellopontine angle. Appl Immunohistochem Mol Morphol 12:230–233PubMed
24.
go back to reference Ho KL, García JH (1992) Colloid cysts of the third ventricle: ultrastructural features are compatible with endodermal derivation. Acta Neuropathol (Berl) 83:605–612CrossRef Ho KL, García JH (1992) Colloid cysts of the third ventricle: ultrastructural features are compatible with endodermal derivation. Acta Neuropathol (Berl) 83:605–612CrossRef
25.
go back to reference Li JC, Brackmann DE, Lo WW, Carberry JN, House JW (1993) Reclassification of aggressive adenomatous mastoid neoplasms as endolymphatic sac tumors. Laryngoscope 103:1342–1348PubMedCrossRef Li JC, Brackmann DE, Lo WW, Carberry JN, House JW (1993) Reclassification of aggressive adenomatous mastoid neoplasms as endolymphatic sac tumors. Laryngoscope 103:1342–1348PubMedCrossRef
26.
go back to reference Megerian CA, Pilch BZ, Bhan AK, McKenna MJ (1997) Differential expression of transthyretin in papillary tumors of the endolymphatic sac and choroid plexus. Laryngoscope 107:216–221PubMedCrossRef Megerian CA, Pilch BZ, Bhan AK, McKenna MJ (1997) Differential expression of transthyretin in papillary tumors of the endolymphatic sac and choroid plexus. Laryngoscope 107:216–221PubMedCrossRef
27.
go back to reference Sharma S, Tan J, Sidhu G, Wieczorek R, Miller DC, Cassai ND (1998) Lung adenocarcinomas metastatic to the brain with and without Ultrastructural evidence of rootlets: an electron microscopic and immunohistochemical study using cytokeratins 7 and 20 and villin. Ultrastruct Pathol 22:385–391PubMedCrossRef Sharma S, Tan J, Sidhu G, Wieczorek R, Miller DC, Cassai ND (1998) Lung adenocarcinomas metastatic to the brain with and without Ultrastructural evidence of rootlets: an electron microscopic and immunohistochemical study using cytokeratins 7 and 20 and villin. Ultrastruct Pathol 22:385–391PubMedCrossRef
28.
go back to reference Pinto MM (1996) Cystic brain lesions: cytologic examination and carcinoembryonic antigen assay in fine needle aspirates. Acta Cytol 40:211–214PubMed Pinto MM (1996) Cystic brain lesions: cytologic examination and carcinoembryonic antigen assay in fine needle aspirates. Acta Cytol 40:211–214PubMed
29.
go back to reference Stoecklein NH, Siegmund A, Scheunemann P, Luebke AM, Erbersdobler A, Verde PE, Eisenberger CF et al (2006) Ep-CAM expression in squamous cell carcinoma of the esophagus: a potential therapeutic target and prognostic marker. BMC Cancer 6:165PubMedCrossRef Stoecklein NH, Siegmund A, Scheunemann P, Luebke AM, Erbersdobler A, Verde PE, Eisenberger CF et al (2006) Ep-CAM expression in squamous cell carcinoma of the esophagus: a potential therapeutic target and prognostic marker. BMC Cancer 6:165PubMedCrossRef
30.
go back to reference Figarella-Branger D, Lepidi H, Poncet C, Gambarelli D, Bianco N, Rougon G, Pellissier JF (1995) Differential expression of cell adhesion molecules (CAM), neural CAM and epithelial cadherin in ependymomas and choroid plexus tumors. Acta Neuropathol (Berl) 89:248–257 Figarella-Branger D, Lepidi H, Poncet C, Gambarelli D, Bianco N, Rougon G, Pellissier JF (1995) Differential expression of cell adhesion molecules (CAM), neural CAM and epithelial cadherin in ependymomas and choroid plexus tumors. Acta Neuropathol (Berl) 89:248–257
Metadata
Title
Choroid plexus Acinar adenoma: a case report
Authors
Daniel Rembao-Bojórquez
Rosalba Vega
Luis Bermúdez-Maldonado
Ramón Gutiérrez
Citlaltepetl Salinas
Martha Tena-Suck
Publication date
01-06-2007
Published in
Journal of Neuro-Oncology / Issue 2/2007
Print ISSN: 0167-594X
Electronic ISSN: 1573-7373
DOI
https://doi.org/10.1007/s11060-006-9304-0

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