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Journal of Neuro-Oncology
Published in: Journal of Neuro-Oncology 2/2007

01-04-2007 | Clinical–Patient Studies

Gefitinib concentrations in human glioblastoma tissue

Authors: Silvia Hofer, Karl Frei

Published in: Journal of Neuro-Oncology | Issue 2/2007

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Excerpt

Delivery of anticancer agents to solid tumors is not well investigated and studies analyzing drug concentrations in human tumor tissue, especially in the brain, are scarce. …
Literature
1.
Hofer S, Frei K, Rutz HP (2006) Gefitinib accumulation in glioblastoma tissue. Cancer Biol Ther 5:483–484PubMedCrossRef
2.
Uhm JH, Haas-Kogan DA, Mischel PS (2006) Epidermal growth factor receptor in glioma: biology, prognosis and clinical trials. In: Educational book, Am Soc Clin Oncol, pp 85–91
3.
Zhao M, Hartke C, Jimeno A et al (2005) Specific method for determination of gefitinib in human plasma, mouse plasma and tissues using high performance liquid chromatography coupled to tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 819:73–80PubMedCrossRef
Metadata
Title
Gefitinib concentrations in human glioblastoma tissue
Authors
Silvia Hofer
Karl Frei
Publication date
01-04-2007
Publisher
Springer US
Published in
Journal of Neuro-Oncology / Issue 2/2007
Print ISSN: 0167-594X
Electronic ISSN: 1573-7373
DOI
https://doi.org/10.1007/s11060-006-9257-3

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